Zobrazeno 1 - 10
of 13
pro vyhledávání: '"P B, Sher"'
Autor:
Paige B. Martin, Yu Kigoshi-Tansho, Roger B. Sher, Gianina Ravenscroft, Jennifer E. Stauffer, Rajesh Kumar, Ryo Yonashiro, Tina Müller, Christopher Griffith, William Allen, Davut Pehlivan, Tamar Harel, Martin Zenker, Denise Howting, Denny Schanze, Eissa A. Faqeih, Naif A. M. Almontashiri, Reza Maroofian, Henry Houlden, Neda Mazaheri, Hamid Galehdari, Ganka Douglas, Jennifer E. Posey, Monique Ryan, James R. Lupski, Nigel G. Laing, Claudio A. P. Joazeiro, Gregory A. Cox
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Defective protein quality control is a key feature of neurodegeneration. Here, the authors show that mutations in Nemf/NEMF, a component of the Ribosome-associated Quality Control complex, have a neurodegenerative effect in mice and may underlie neur
Externí odkaz:
https://doaj.org/article/b025566dc73a49eba1468daddca86ccd
Autor:
Alison E. Burkett, Sophia B. Sher, Chirag R. Patel, Isam Ildin-Eltoum, Deepti Dhall, Camilla Margaroli, Shajan Peter, Goo Lee, Prachi Bajpai, Paul V. Benson, Upender Manne, Sameer Al Diffalha
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
It is now known that COVID-19 not only involves the lungs, but other organs as well including the gastrointestinal tract. Although clinic-pathological features are well-described in lungs, the histopathologic features of gastrointestinal involvement
Externí odkaz:
https://doaj.org/article/5bf91ac22b5543a9becdf29e7c77411b
Autor:
Guillermo M. Alexander, Terry D. Heiman-Patterson, Frank Bearoff, Roger B. Sher, Laura Hennessy, Shannon Terek, Nicole Caccavo, Gregory A. Cox, Vivek M. Philip, Elizabeth A. Blankenhorn
Publikováno v:
PLoS ONE, Vol 17, Iss 9 (2022)
Amyotrophic lateral sclerosis (ALS) is the most common degenerative motor neuron disorder. Although most cases of ALS are sporadic, 5–10% of cases are familial, with mutations associated with over 40 genes. There is variation of ALS symptoms within
Externí odkaz:
https://doaj.org/article/c5e45c28b7ff4ee8a44b61046dc065b0
Autor:
Roger B Sher
Publikováno v:
Neural Regeneration Research, Vol 12, Iss 6, Pp 902-905 (2017)
Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease that results in the progressive death of motor neurons, leading to paralysis and eventual death. There is presently no cure for ALS, and only two drugs are available, neit
Externí odkaz:
https://doaj.org/article/8b80057bafdc41319018c102ef861b65
Autor:
Paige B. Martin, Yu Kigoshi-Tansho, Roger B. Sher, Gianina Ravenscroft, Jennifer E. Stauffer, Rajesh Kumar, Ryo Yonashiro, Tina Müller, Christopher Griffith, William Allen, Davut Pehlivan, Tamar Harel, Martin Zenker, Denise Howting, Denny Schanze, Eissa A. Faqeih, Naif A. M. Almontashiri, Reza Maroofian, Henry Houlden, Neda Mazaheri, Hamid Galehdari, Ganka Douglas, Jennifer E. Posey, Monique Ryan, James R. Lupski, Nigel G. Laing, Claudio A. P. Joazeiro, Gregory A. Cox
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/815477d2acf44130a569e4fe56c48e43
Autor:
Terry D Heiman-Patterson, Elizabeth P Blankenhorn, Roger B Sher, Juliann Jiang, Priscilla Welsh, Meredith C Dixon, Jeremy I Jeffrey, Philip Wong, Gregory A Cox, Guillermo M Alexander
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0117848 (2015)
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease primarily affecting motor neurons in the central nervous system. Although most cases of ALS are sporadic, about 5-10% of cases are familial (FALS) with approximately 20% of FALS cause
Externí odkaz:
https://doaj.org/article/f15da2421d78404091f24e11313c9f4d
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23498 (2011)
Rhabdomyosarcomas (RSCs) are skeletal muscle neoplasms found in humans and domestic mammals. The A/J inbred strain developed a high frequency (between 70-80%) of adult pleomorphic type (APT) RSC at >20 months of age while BALB/cByJ also develop RSC b
Externí odkaz:
https://doaj.org/article/94ad1b85d88a4e2e9bfdcfc2efd03fdb
Publikováno v:
Journal of Lipid Research, Vol 4, Iss 1, Pp 34-38 (1963)
Palmitic acid-1-C14 was given intravenously to volunteer subjects before, and toward the end of, 35–45 min of exercise. The fractional turnover rate and total turnover rates for plasma free fatty acids were greater during exercise. The concentratio
Externí odkaz:
https://doaj.org/article/7bcf326999c34e7bbf64f6c65a2b5acd
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Publikováno v:
Journal of neuro-oncology. 10(1)
To investigate whether brain tumors secrete a factor(s) responsible for peritumoral brain edema, we studied the effect of conditioned medium from cultured C6 glioma cells on rat brain capillary permeability. Three different fractions of conditioned m