Zobrazeno 1 - 10
of 26
pro vyhledávání: '"P B, Bitterman"'
Autor:
Libang Yang, Adam Gilbertsen, Hong Xia, Alexey Benyumov, Karen Smith, Jeremy Herrera, Emil Racila, Peter B. Bitterman, Craig A. Henke
Publikováno v:
JCI Insight, Vol 8, Iss 4 (2023)
Hypoxia is a sentinel feature of idiopathic pulmonary fibrosis (IPF). The IPF microenvironment contains high lactate levels, and hypoxia enhances cellular lactate production. Lactate, acting through the GPR81 lactate receptor, serves as a signal mole
Externí odkaz:
https://doaj.org/article/3154f58106d74c148d746f3dce91fdab
Publikováno v:
APL Bioengineering, Vol 5, Iss 4, Pp 046102-046102-12 (2021)
Idiopathic pulmonary fibrosis (IPF) is a lethal lung disease targeting the alveolar gas exchange apparatus, leading to death by asphyxiation. IPF progresses on a tissue scale through aberrant matrix remodeling, enhanced cell contraction, and subseque
Externí odkaz:
https://doaj.org/article/19c7b835430d42d488c0ad731d4140d7
Autor:
Libang Yang, Hong Xia, Karen Smith, Adam Gilbertsen, Daniel Beisang, Jonathan Kuo, Peter B. Bitterman, Craig A. Henke
Publikováno v:
JCI Insight, Vol 6, Iss 9 (2021)
Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic lung disease. We previously identified fibrogenic mesenchymal progenitor cells (MPCs) in the lungs of patients with IPF who serve as drivers of progressive fibrosis. Recent single-cell RNA
Externí odkaz:
https://doaj.org/article/e5202f9518134fa193ed10cf1c380cf6
Autor:
Aleksandra M. Ochnik, Mark S. Peterson, Svetlana V. Avdulov, Annabell S. Oh, Peter B. Bitterman, Douglas Yee
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 18, Iss 2, Pp 100-110 (2016)
Background: Control of mRNA translation is fundamentally altered in cancer. Insulin-like growth factor-I (IGF-I) signaling regulates key translation mediators to modulate protein synthesis (e.g. eIF4E, 4E-BP1, mTOR, and S6K1). Importantly the Amplifi
Externí odkaz:
https://doaj.org/article/1af83b619c474e788717859b718c1f3b
Autor:
Maneesh Bhargava, Trisha L Becker, Kevin J Viken, Pratik D Jagtap, Sanjoy Dey, Michael S Steinbach, Baolin Wu, Vipin Kumar, Peter B Bitterman, David H Ingbar, Christine H Wendt
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e109713 (2014)
Acute Respiratory Distress Syndrome (ARDS) continues to have a high mortality. Currently, there are no biomarkers that provide reliable prognostic information to guide clinical management or stratify risk among clinical trial participants. The object
Externí odkaz:
https://doaj.org/article/20866569ca6d47c8919d99c184f90756
Autor:
Ola Larsson, Deanna Diebold, Danhua Fan, Mark Peterson, Richard Seonghun Nho, Peter B Bitterman, Craig A Henke
Publikováno v:
PLoS ONE, Vol 3, Iss 9, p e3220 (2008)
BACKGROUND:As a group, fibroproliferative disorders of the lung, liver, kidney, heart, vasculature and integument are common, progressive and refractory to therapy. They can emerge following toxic insults, but are frequently idiopathic. Their enigmat
Externí odkaz:
https://doaj.org/article/4067f08ddeea43d4b1dadac64e666836
Autor:
P. B. Bitterman
Publikováno v:
Update in Intensive Care and Emergency Medicine ISBN: 9783642645327
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::540ae2349521758bc7f67c0b0b1447b2
https://doi.org/10.1007/978-3-642-60733-2_8
https://doi.org/10.1007/978-3-642-60733-2_8
Publikováno v:
Journal of neurosurgery. 82(6)
✓ A 38-year-old man receiving cyclosporine A after bilateral lung transplantation for cystic fibrosis presented with cortical blindness, generalized seizures, and cerebellar edema. Progressive brainstem compression necessitated emergency posterior
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b28f35b1480c1176fdbe723518aa8adf
https://pubmed.ncbi.nlm.nih.gov/7760181
https://pubmed.ncbi.nlm.nih.gov/7760181
Autor:
K R, Harmon, C J, Witkop, J G, White, R A, King, M, Peterson, D, Moore, J, Tashjian, W A, Marinelli, P B, Bitterman
Publikováno v:
The Journal of laboratory and clinical medicine. 123(4)
Peptides that modulate mesenchymal cell function have been detected in the fibrotic lung disorders once physiologic dysfunction is present. Despite this close association with manifest disease, their role in initiating alveolar remodeling remains unk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::aaea6efbcadd4086d5284aa9aa8c39cd
https://pubmed.ncbi.nlm.nih.gov/8145011
https://pubmed.ncbi.nlm.nih.gov/8145011
Autor:
J M, Fox, K, Conklin, L, Chiang, J, Whittsett, M, King, W A, Marinelli, K R, Harmon, C A, Henke, P B, Bitterman
Publikováno v:
Chest. 105
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5f4aa0a527418902330ce71b8b48c7f4
https://pubmed.ncbi.nlm.nih.gov/8131605
https://pubmed.ncbi.nlm.nih.gov/8131605