Zobrazeno 1 - 10
of 1 164
pro vyhledávání: '"P A Pienta"'
Autor:
Phan, Trung V., Li, Shengkai, Howe, Benjamin, Amend, Sarah R., Pienta, Kenneth J., Brown, Joel S., Gatenby, Robert A., Frangakis, Constantine, Austin, Robert H., Keverkidis, Ioannis G.
With the oncologist acting as the ``game leader'', we employ a Stackelberg game-theoretic model involving multiple populations to study prostate cancer. We refine the drug dosing schedule using an empirical Bayes feed-forward analysis, based on clini
Externí odkaz:
http://arxiv.org/abs/2410.16005
Autor:
Tyler M. Bauer, MD, Michael J. Pienta, MD, Xiaoting Wu, PhD, Michael P. Thompson, PhD, Robert B. Hawkins, MD, Andrew L. Pruitt, MD, Alphonse Delucia, III, MD, Shelly C. Lall, MD, Francis D. Pagani, MD, PhD, Donald S. Likosky, PhD
Publikováno v:
JTCVS Open, Vol 20, Iss , Pp 101-111 (2024)
Objective: Cardiac surgeons experience unpredictable overnight operative responsibilities, with variable rest before same-day, first-start scheduled cases. This study evaluated the frequency and associated impact of a surgeon's overnight operative wo
Externí odkaz:
https://doaj.org/article/c678b1d1014d4f40823629532621b97d
Autor:
Zhao, Chen, Xu, Zhihui, Jiang, Jingfeng, Esposito, Michele, Pienta, Drew, Hung, Guang-Uei, Zhou, Weihua
Semantic labeling of coronary arterial segments in invasive coronary angiography (ICA) is important for automated assessment and report generation of coronary artery stenosis in the computer-aided diagnosis of coronary artery disease (CAD). Inspired
Externí odkaz:
http://arxiv.org/abs/2301.04733
Autor:
Meng, Yinghui, Du, Zhenglong, Zhao, Chen, Dong, Minghao, Pienta, Drew, Xu, Zhihui, Zhou, Weihua
Accurate extraction of coronary arteries from invasive coronary angiography (ICA) is important in clinical decision-making for the diagnosis and risk stratification of coronary artery disease (CAD). In this study, we develop a method using deep learn
Externí odkaz:
http://arxiv.org/abs/2206.12300
Autor:
Philip Sutera, MD, Matthew P. Deek, MD, Rebecca A. Deek, MS, Ozan Cem Guler, MD, Pervin Hurmuz, MD, Mehmet Reyhan, MD, Steven Rowe, MD, PhD, Noura Radwan, MD, Shirl Dipasquale, MSRN, William T. Hrinivich, PhD, Kathryn Lowe, MA, Lei Ren, PhD, Biren Saraiya, MD, Ronald Ennis, MD, Lara Hathout, MD, Tina Mayer, MD, Theodore L. Deweese, MD, Daniel Y. Song, MD, Ana Kiess, MD, Ezgi Oymak, MD, Kenneth Pienta, MD, Felix Feng, MD, Martin Pomper, MD, PhD, Gokhan Ozyigit, MD, Phuoc T. Tran, MD, PhD, Cem Onal, MD, Ryan M. Phillips, MD, PhD
Publikováno v:
Advances in Radiation Oncology, Vol 9, Iss 7, Pp 101507- (2024)
Purpose: Emerging data suggest that metastasis-directed therapy (MDT) improves outcomes in patients with oligometastatic castration-sensitive prostate cancer (omCSPC). Prostate-specific membrane antigen positron emission tomography (PSMA-PET) can det
Externí odkaz:
https://doaj.org/article/919f5deb98734f49825fc1c228a4a377
Autor:
Tyler M. Bauer, MD, Michael Pienta, MD, MS, Xiaoting Wu, PhD, Eric J. Lehr, MD, PhD, Glenn J.R. Whitman, MD, Robert S. Kramer, MD, James Brevig, MD, Francis D. Pagani, MD, PhD, Donald S. Likosky, PhD
Publikováno v:
JTCVS Open, Vol 16, Iss , Pp 123-138 (2023)
Objective: This study evaluated interhospital variability and determinants of failure-to-rescue for patients undergoing surgical aortic valve replacement. Methods: An observational study was conducted among 28,842 patients undergoing aortic valve rep
Externí odkaz:
https://doaj.org/article/ea8fe46c222f48a6b63235829a13d9e2
Autor:
Wanyoung Lim, Inwoo Hwang, Jiande Zhang, Zhenzhong Chen, Jeonghun Han, Jaehyung Jeon, Bon-Kyoung Koo, Sangmin Kim, Jeong Eon Lee, Youngkwan Kim, Kenneth J Pienta, Sarah R Amend, Robert H Austin, Jee-Yin Ahn, Sungsu Park
Publikováno v:
eLife, Vol 12 (2024)
Chemoresistance is a major cause of treatment failure in many cancers. However, the life cycle of cancer cells as they respond to and survive environmental and therapeutic stress is understudied. In this study, we utilized a microfluidic device to in
Externí odkaz:
https://doaj.org/article/938e5cfba98a4d9f955a45c8b7d44e66
Autor:
Ryan T. Rego, Yuri Zhukov, Kyrani A. Reneau, Amy Pienta, Kristina L. Rice, Patrick Brady, Geoffrey H. Siwo, Peninah Wanjiku Wachira, Amina Abubakar, Ken Kollman, Akbar K. Waljee
Publikováno v:
BMC Medical Research Methodology, Vol 23, Iss 1, Pp 1-10 (2023)
Abstract Background Factors influencing the health of populations are subjects of interdisciplinary study. However, datasets relevant to public health often lack interdisciplinary breath. It is difficult to combine data on health outcomes with datase
Externí odkaz:
https://doaj.org/article/600ad5f2d2ff4fc88f84cef4bf0a8ff7
Autor:
Anuraag Bukkuri, Kenneth J. Pienta, Robert H. Austin, Emma U. Hammarlund, Sarah R. Amend, Joel S. Brown
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract The polyaneuploid cancer cell (PACC) state promotes cancer lethality by contributing to survival in extreme conditions and metastasis. Recent experimental evidence suggests that post-therapy PACC-derived recurrent populations display cross-r
Externí odkaz:
https://doaj.org/article/bcbd6c09da064051a756848a4f23f88c
Autor:
Liang Dong, Mingxiao Feng, Morgan D. Kuczler, Kengo Horie, Chi‐Ju Kim, Zehua Ma, Kara Lombardo, Heather Lyons, Sarah R. Amend, Max Kates, Trinity J. Bivalacqua, David McConkey, Wei Xue, Woonyoung Choi, Kenneth J. Pienta
Publikováno v:
Journal of Extracellular Vesicles, Vol 13, Iss 2, Pp n/a-n/a (2024)
Abstract mRNA‐based molecular subtypes have implications for bladder cancer prognosis and clinical benefit from certain therapies. Whether small extracellular vesicles (sEVs) can reflect bladder cancer molecular subtypes is unknown. We performed wh
Externí odkaz:
https://doaj.org/article/ece9db0272414a03a5178ffe2e145ee8