Zobrazeno 1 - 10
of 78
pro vyhledávání: '"P A J, de Groot"'
Autor:
Aafke J. de Groot, Elizabeth M. Wattel, Romke van Balen, Cees M.P.M. Hertogh, Johannes C. van der Wouden
Publikováno v:
Annals of Geriatric Medicine and Research, Vol 27, Iss 4, Pp 301-309 (2023)
Background The short Dutch Safety Management Screening (DSMS) is applied at hospital admission of all patients aged >70 years to assess vulnerability. Screening of four geriatric domains aims to prevent adverse outcomes and may support targeted disch
Externí odkaz:
https://doaj.org/article/7ece4542cfdc4ccdbc7087eacfac16e4
Autor:
Chiara Aloise, Jelle G Schipper, Arno van Vliet, Judith Oymans, Tim Donselaar, Daniel L Hurdiss, Raoul J de Groot, Frank J M van Kuppeveld
Publikováno v:
PLoS Pathogens, Vol 19, Iss 8, p e1011582 (2023)
The nucleocapsid protein N of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) enwraps and condenses the viral genome for packaging but is also an antagonist of the innate antiviral defense. It suppresses the integrated stress response (I
Externí odkaz:
https://doaj.org/article/f7de8a47b87c4e9e88b06cd5bac75e80
Autor:
Marina Marcet-Houben, María Alvarado, Ewa Ksiezopolska, Ester Saus, Piet W. J. de Groot, Toni Gabaldón
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-17 (2022)
Abstract Background Candida glabrata is an opportunistic yeast pathogen thought to have a large genetic and phenotypic diversity and a highly plastic genome. However, the lack of chromosome-level genome assemblies representing this diversity limits o
Externí odkaz:
https://doaj.org/article/24a60922742d4dd48b09e64fd97109b0
Autor:
María Alvarado, Jesús Alberto Gómez-Navajas, María Teresa Blázquez-Muñoz, Emilia Gómez-Molero, Carmen Berbegal, Elena Eraso, Gertjan Kramer, Piet W J De Groot
Publikováno v:
PLoS Pathogens, Vol 19, Iss 5, p e1011158 (2023)
The pathogenic yeast Pichia kudriavzevii, previously known as Candida krusei, is more distantly related to Candida albicans than clinically relevant CTG-clade Candida species. Its cell wall, a dynamic organelle that is the first point of interaction
Externí odkaz:
https://doaj.org/article/5dec5521324f42fc80d8934e6c327373
Autor:
Chunyan Wang, Emma L. Hesketh, Tatiana M. Shamorkina, Wentao Li, Peter J. Franken, Dubravka Drabek, Rien van Haperen, Sarah Townend, Frank J. M. van Kuppeveld, Frank Grosveld, Neil A. Ranson, Joost Snijder, Raoul J. de Groot, Daniel L. Hurdiss, Berend-Jan Bosch
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Human coronavirus OC43 causes respiratory disease and is maintained in the human population through recurring infections. Here, by extensive structural analyses, the authors provide insights into the binding sites and breadth of neutralizing antibodi
Externí odkaz:
https://doaj.org/article/a254f75862064c1d9048eaf549552960
Autor:
Ozair Abawi, Emma C. Koster, Mila S. Welling, Sanne C.M. Boeters, Elisabeth F. C. van Rossum, Mieke M. van Haelst, Bibian van der Voorn, Cornelis J. de Groot, Erica L. T. van den Akker
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
BackgroundPediatric obesity is a multifactorial disease which can be caused by underlying medical disorders arising from disruptions in the hypothalamic leptin-melanocortin pathway, which regulates satiety and energy expenditure.AimTo investigate and
Externí odkaz:
https://doaj.org/article/dc1b964dac0f422c8ef943aa804dd0ad
Autor:
M. S. Walma, S. J. Rombouts, L. J. H. Brada, I. H. Borel Rinkes, K. Bosscha, R. C. Bruijnen, O. R. Busch, G. J. Creemers, F. Daams, R. M. van Dam, O. M. van Delden, S. Festen, P. Ghorbani, D. J. de Groot, J. W. B. de Groot, N. Haj Mohammad, R. van Hillegersberg, I. H. de Hingh, M. D’Hondt, E. D. Kerver, M. S. van Leeuwen, M. S. Liem, K. P. van Lienden, M. Los, V. E. de Meijer, M. R. Meijerink, L. J. Mekenkamp, C. Y. Nio, I. Oulad Abdennabi, E. Pando, G. A. Patijn, M. B. Polée, J. F. Pruijt, G. Roeyen, J. A. Ropela, M. W. J. Stommel, J. de Vos-Geelen, J. J. de Vries, E. M. van der Waal, F. J. Wessels, J. W. Wilmink, H. C. van Santvoort, M. G. Besselink, I. Q. Molenaar, for the Dutch Pancreatic Cancer Group
Publikováno v:
Trials, Vol 22, Iss 1, Pp 1-12 (2021)
Abstract Background Approximately 80% of patients with locally advanced pancreatic cancer (LAPC) are treated with chemotherapy, of whom approximately 10% undergo a resection. Cohort studies investigating local tumor ablation with radiofrequency ablat
Externí odkaz:
https://doaj.org/article/3d301f6bd2bd4bac89f7f45ee7d3f040
Autor:
Cees M P M Hertogh, Johannes C van der Wouden, Elise P Jansma, Dennis Visser, Elizabeth M Wattel, Karin H L Gerrits, Franka J M Meiland, Aafke J de Groot, Ewout B Smit
Publikováno v:
BMJ Open, Vol 12, Iss 5 (2022)
Objectives To present an overview of effectiveness and training characteristics of physical training on aerobic fitness, compared with alternative or no training, in adults aged over 65 years with various health statuses, providing a basis for guidel
Externí odkaz:
https://doaj.org/article/ec3d38bb7c8248f3a4248782511110fc
Autor:
Alba Ruiz-Gaitán, Ignacio Sigona-Giangreco, José Manuel Pérez-Royo, Victor Garcia-Bustos, Marta García-Hita, Eulogio Valentín-Gómez, Salvador Giner Almaraz, Piet W. J. de Groot, Javier Pemán
Publikováno v:
Diagnostics, Vol 13, Iss 2, p 231 (2023)
Introduction:Candida auris is a major threat to public health. Rapid detection is essential for early treatment and transmission control. The use of chromogenic media allows the presumptive identification of this new species. The aim of this study is
Externí odkaz:
https://doaj.org/article/d732e0f83b78463897c557db553887fb
Autor:
Jiska van Schaik, Mila S. Welling, Corjan J. de Groot, Judith P. van Eck, Alicia Juriaans, Marcella Burghard, Sebastianus B. J. Oude Ophuis, Boudewijn Bakker, Wim J. E. Tissing, Antoinette Y. N. Schouten-van Meeteren, Erica L. T. van den Akker, Hanneke M. van Santen
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
IntroductionHypothalamic obesity (HO) in children has severe health consequences. Lifestyle interventions are mostly insufficient and currently no drug treatment is approved for children with HO. Amphetamines are known for their stimulant side-effect
Externí odkaz:
https://doaj.org/article/3bfe15bb5e0d4880a81c5dfb2c393e8d