Zobrazeno 1 - 10
of 77
pro vyhledávání: '"P A F, Madden"'
Publikováno v:
Translational Oncology, Vol 46, Iss , Pp 102025- (2024)
New treatments are urgently required for triple-negative breast cancer (TNBC). As TP53 is mutated in approximately 80% of TNBC, it is theoretically an attractive target for new drugs for this disease. Arsenic trioxide (ATO), which is used to treat pr
Externí odkaz:
https://doaj.org/article/75039994030f4ff8baa64d4d87ad5977
Publikováno v:
Health Science Reports, Vol 7, Iss 7, Pp n/a-n/a (2024)
Abstract Background Suicide is a major driver of mortality among college students and is the leading cause of death among American Indian, Alaska Native, and Native Hawaiian (AI/AN/NH) young adults. Methods Data on suicidal ideation, suicide attempt,
Externí odkaz:
https://doaj.org/article/ec171aa9058a47428877bd34514139a1
Autor:
Nicola Cosgrove, Alex J. Eustace, Peter O’Donovan, Stephen F. Madden, Bruce Moran, John Crown, Brian Moulton, Patrick G. Morris, Liam Grogan, Oscar Breathnach, Colm Power, Michael Allen, Janice M. Walshe, Arnold D. Hill, Anna Blümel, Darren O’Connor, Sudipto Das, Małgorzata Milewska, Joanna Fay, Elaine Kay, Sinead Toomey, Bryan T. Hennessy, Simon J. Furney
Publikováno v:
npj Breast Cancer, Vol 9, Iss 1, Pp 1-16 (2023)
Abstract HER2-positive (HER2+) breast cancer accounts for 20–25% of all breast cancers. Predictive biomarkers of neoadjuvant therapy response are needed to better identify patients with early stage disease who may benefit from tailored treatments i
Externí odkaz:
https://doaj.org/article/2aa94f4a6ce8446ea48464a6049912d0
Publikováno v:
Substance Abuse: Research and Treatment, Vol 17 (2023)
Introduction: This study examines factors associated with psychostimulant misuse, including polysubstance use and social factors, among the understudied American Indian/Alaska Native/Native Hawaiian (AI/AN/NH) college student population. Methods: Dat
Externí odkaz:
https://doaj.org/article/423c34ade417488e89d33b699251bf87
Autor:
Elizabeth Daly Hicks, Noah O. Agada, Tyler R. Yates, Matthew S. Kelly, Jonathan S. Tam, Ronald M. Ferdman, Louis R. Dibernardo, John F. Madden, M. Anthony Moody, Mary Louise Markert
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Children with complete DiGeorge anomaly (cDGA) have congenital athymia, resulting in severe T cell immunodeficiency and susceptibility to a broad range of infections. We report the clinical course, immunologic phenotypes, treatment, and outcomes of t
Externí odkaz:
https://doaj.org/article/e371aef595714601ae24b1d9edcb83d4
Autor:
Sandra Roche, Patricia Gaule, Deirdre Winrow, Nupur Mukherjee, Fiona O'Neill, Neil T Conlon, Justine Meiller, Denis M Collins, Alexandra Canonici, Mohammed Ibrahim Fawsi, Alejandra Estepa-Fernández, Stephen F Madden, John Crown, Norma O'Donovan, Alex J Eustace
Publikováno v:
PLoS ONE, Vol 18, Iss 3, p e0282512 (2023)
Triple Negative Breast Cancer (TNBC), a subtype of breast cancer, has fewer successful therapeutic therapies than other types of breast cancer. Insulin-like growth factor receptor 1 (IGF1R) and the Insulin receptor (IR) are associated with poor outco
Externí odkaz:
https://doaj.org/article/b9644b158fb94f80a2b68dadca1eef19
Publikováno v:
SSM: Qualitative Research in Health, Vol 2, Iss , Pp 100161- (2022)
Despite a substantial evidence base for effectiveness, medications for opioid use disorder (MOUD) are often stigmatized. Even healthcare professionals working in substance use treatment may describe these medications as undesirable forms of medical i
Externí odkaz:
https://doaj.org/article/a20ed3a572254378a02952aba229a5ac
Autor:
Pierce Geoghegan, Jennifer Clarke, Grace Hogan, Aoife Keogh, Hannah Marsh, Karen Donnelly, Natalie McEvoy, Aoife Doolan, Stephen F. Madden, Ignacio Martin‐Loeches, Michael Power, John G. Laffey, Gerard F. Curley
Publikováno v:
Physiological Reports, Vol 10, Iss 17, Pp n/a-n/a (2022)
Abstract Split ventilation (using a single ventilator to ventilate multiple patients) is technically feasible. However, connecting two patients with acute respiratory distress syndrome (ARDS) and differing lung mechanics to a single ventilator is con
Externí odkaz:
https://doaj.org/article/8af2340459a0475e9a04c2002b81338c
Autor:
Eileen E. Parkes, Matthew P. Humphries, Elaine Gilmore, Fatima A. Sidi, Victoria Bingham, Su M. Phyu, Stephanie Craig, Catherine Graham, Joseph Miller, Daryl Griffin, Manuel Salto-Tellez, Stephen F. Madden, Richard D. Kennedy, Samuel F. Bakhoum, Stephen McQuaid, Niamh E. Buckley
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-11 (2021)
Abstract STING signaling in cancer is a crucial component of response to immunotherapy and other anti-cancer treatments. Currently, there is no robust method of measuring STING activation in cancer. Here, we describe an immunohistochemistry-based ass
Externí odkaz:
https://doaj.org/article/6790f073307d4fffbb5fb02a2f06cc1f
Autor:
Fares Qeadan, Erin F Madden, Nana A Mensah, Benjamin Tingey, Jalene Herron, Alexandra Hernandez-Vallant, Kamilla L Venner, Kevin English, Amruta Dixit
Publikováno v:
BMJ Open, Vol 12, Iss 5 (2022)
Objectives The rate of drug overdose deaths in the USA has more than tripled since the turn of the century, and rates are disproportionately high among the American Indian/Alaska Native (AI/AN) population. Little is known about the overall historical
Externí odkaz:
https://doaj.org/article/4deff7eda7054b46bb003cd45ba12946