Zobrazeno 1 - 10 of 115 pro vyhledávání: '"P A E, Sillevis Smitt"'
1
Akademický článek
Metabotropic glutamate receptor 1 is associated with unfavorable prognosis in ER-negative and triple-negative breast cancer
Autor: Anna E. M. Bastiaansen, A. Mieke Timmermans, Marcel Smid, Carolien H. M. van Deurzen, Esther S. P. Hulsenboom, Wendy J. C. Prager-van der Smissen, Renée Foekens, Anita M. A. C. Trapman-Jansen, Peter A. E. Sillevis Smitt, Theo M. Luider, John W. M. Martens, Martijn M. vanDuijn
Publikováno v: Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Abstract New therapies are an urgent medical need in all breast cancer subgroups. Metabotropic glutamate receptor 1 (mGluR1) is suggested as a potential new molecular target. We examined the prevalence mGluR1 expression in different clinically releva
Externí odkaz: https://doaj.org/article/857bf571bd7b4be593d8884fd1a9208e
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2
Akademický článek
Low-grade glioma harbors few CD8 T cells, which is accompanied by decreased expression of chemo-attractants, not immunogenic antigens
Autor: Bas Weenink, Kaspar Draaisma, Han Z. Ooi, Johan M. Kros, Peter A. E. Sillevis Smitt, Reno Debets, Pim J. French
Publikováno v: Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Abstract In multiple tumor types, prediction of response to immune therapies relates to the presence, distribution and activation state of tumor infiltrating lymphocytes (TILs). Although such therapies are, to date, unsuccessful in gliomas, little is
Externí odkaz: https://doaj.org/article/8d69b7caf1204a69af1c62b11ef298e8
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3
Akademický článek
IDH1-mutated transgenic zebrafish lines: An in-vivo model for drug screening and functional analysis.
Autor: Ya Gao, Maurice de Wit, Eduard A Struys, Herma C Z van der Linde, Gajja S Salomons, Martine L M Lamfers, Rob Willemsen, Peter A E Sillevis Smitt, Pim J French
Publikováno v: PLoS ONE, Vol 13, Iss 6, p e0199737 (2018)
INTRODUCTION:The gene encoding isocitrate dehydrogenase 1 (IDH1) is frequently mutated in several tumor types including gliomas. The most prevalent mutation in gliomas is a missense mutation leading to a substitution of arginine with histidine at the
Externí odkaz: https://doaj.org/article/0fc8f271716f461b9746cc9cb4fc90fb
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4
Akademický článek
Immune Repertoire after Immunization As Seen by Next-Generation Sequencing and Proteomics
Autor: Martijn M. VanDuijn, Lennard J. Dekker, Wilfred F. J. van IJcken, Peter A. E. Sillevis Smitt, Theo M. Luider
Publikováno v: Frontiers in Immunology, Vol 8 (2017)
The immune system produces a diverse repertoire of immunoglobulins in response to foreign antigens. During B-cell development, VDJ recombination and somatic mutations generate diversity, whereas selection processes remove it. Using both proteomic and
Externí odkaz: https://doaj.org/article/2e7c42c101a64548bd371ef4e1b6643d
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5
Akademický článek
Peptides from the variable region of specific antibodies are shared among lung cancer patients.
Autor: Dominique de Costa, Ingrid Broodman, Wim Calame, Christoph Stingl, Lennard J M Dekker, René M Vernhout, Harry J de Koning, Henk C Hoogsteden, Peter A E Sillevis Smitt, Rob J van Klaveren, Theo M Luider, Martijn M Vanduijn
Publikováno v: PLoS ONE, Vol 9, Iss 5, p e96029 (2014)
Late diagnosis of lung cancer is still the main reason for high mortality rates in lung cancer. Lung cancer is a heterogeneous disease which induces an immune response to different tumor antigens. Several methods for searching autoantibodies have bee
Externí odkaz: https://doaj.org/article/c8899289cfd94da383c5aa6189c2c894
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6
Akademický článek
Proteomics comparison of cerebrospinal fluid of relapsing remitting and primary progressive multiple sclerosis.
Autor: Marcel P Stoop, Vaibhav Singh, Lennard J Dekker, Mark K Titulaer, Christoph Stingl, Peter C Burgers, Peter A E Sillevis Smitt, Rogier Q Hintzen, Theo M Luider
Publikováno v: PLoS ONE, Vol 5, Iss 8, p e12442 (2010)
BACKGROUND: Based on clinical representation of disease symptoms multiple sclerosis (MScl) patients can be divided into two major subtypes; relapsing remitting (RR) MScl (85-90%) and primary progressive (PP) MScl (10-15%). Proteomics analysis of cere
Externí odkaz: https://doaj.org/article/ab85523534354b7e8ec005a830c8a2e3
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7
From VGKC to LGI1 and Caspr2 encephalitis: The evolution of a disease entity over time
Autor: Marco W.J. Schreurs, Maarten J. Titulaer, A. van Sonderen, P. A. E. Sillevis Smitt, Paul W. Wirtz
Publikováno v: Autoimmunity Reviews, 15(10), 970-974. Elsevier
A wide variety of clinical syndromes has been associated with antibodies to voltage-gated potassium channels (VGKCs). Six years ago, it was discovered that patients do not truly have antibodies to potassium channels, but to associated proteins. This
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5663ca7d4883fa17c04e355b450eae8
https://doi.org/10.1016/j.autrev.2016.07.018
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8
Expression-based intrinsic glioma subtypes are prognostic in low-grade gliomas of the EORTC22033-26033 clinical trial
Autor: Lale Erdem-Eraslan, Roger Stupp, Pim J. French, Th Gorlia, Gail Ryan, Olivier Chinot, F. Dhermain, J.M.M. Gijtenbeek, Monika E. Hegi, P. A. E. Sillevis Smitt, Johan M. Kros, Maaike J. Vos, Carmen Balana, M. Ben Hassel, M. E. van Linde, Gao Y, Khê Hoang-Xuan, A. von Deimling, Brigitta G. Baumert, A. A. Brandes, Bas Weenink, Roelien H. Enting, Warren P. Mason, M. J. van den Bent
Publikováno v: Gao, Y, Weenink, B, van den Bent, M J, Erdem-Eraslan, L, Kros, J M, Sillevis Smitt, P A E, Hoang-Xuan, K, Brandes, A A, Vos, M, Dhermain, F, Enting, R, Ryan, G F, Chinot, O, Ben Hassel, M, van Linde, M E, Mason, W P, Gijtenbeek, J M M, Balana, C, von Deimling, A, Gorlia, T, Stupp, R, Hegi, M E, Baumert, B G & French, P J 2018, ' Expression-based intrinsic glioma subtypes are prognostic in low-grade gliomas of the EORTC22033-26033 clinical trial ', European Journal of Cancer, vol. 94, pp. 168-178 . https://doi.org/10.1016/j.ejca.2018.02.023
European Journal of Cancer
European Journal of Cancer, 2018, 94, pp.168-178. ⟨10.1016/j.ejca.2018.02.023⟩
European Journal of Cancer, 94, 168-178. Elsevier Ltd.
European Journal of Cancer, Elsevier, 2018, 94, pp.168-178. 〈10.1016/j.ejca.2018.02.023〉
European Journal of Cancer, 94, pp. 168-178
European Journal of Cancer, Elsevier, 2018, 94, pp.168-178. ⟨10.1016/j.ejca.2018.02.023⟩
European Journal of Cancer, 94, 168-178
European Journal of Cancer, 94, 168-178. Pergamon
European Journal of Cancer, 94, 168-178. ELSEVIER SCI LTD
European journal of cancer (Oxford, England, 94, 168-178. Elsevier Limited
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
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Introduction: The European Organisation for Research and Treatment of Cancer (EORTC) 22033-26033 clinical trial (NCT00182819) investigated whether initial temozolomide (TMZ) chemotherapy confers survival advantage compared with radiotherapy (RT) in l
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4162fea92c3a37e28fc354eb2873bec4
https://research.vumc.nl/en/publications/58893c65-c797-4e1d-be63-f6fd69c6ec74
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10
Gene expression profiles of gliomas in formalin-fixed paraffin-embedded material
Autor: M. J. van den Bent, Paul H. C. Eilers, J J de Rooi, Pim J. French, P. A. E. Sillevis Smitt, Lonneke A.M. Gravendeel
Publikováno v: British Journal of Cancer, 106(3), 538-545. Nature Publishing Group
British Journal of Cancer
BACKGROUND: We have recently demonstrated that expression profiling is a more accurate and objective method to classify gliomas than histology. Similar to most expression profiling studies, our experiments were performed using fresh frozen (FF) gliom
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3d4b88b05418fa0b1add12072cf7ee4
https://hdl.handle.net/1765/66576
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