Zobrazeno 1 - 10
of 62
pro vyhledávání: '"P A, Cossum"'
Autor:
A.J. Carrillo-Muñoz, O. del Valle, T. L. Wallace, Guillermo Quindós, P. A. Cossum, Y. Miranda, C. Tur, María Teresa Ruesga
Publikováno v:
The Journal of antimicrobial chemotherapy. 44(3)
The in-vitro susceptibilities of 120 clinical isolates of yeasts to liposomal nystatin were compared with those to amphotericin B lipid complex (ABLC), liposomal amphotericin B (LAB), amphotericin B cholesteryl sulphate (ABCD), amphotericin B desoxyc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::129248e3a958ca5c4c75bd4427a95df6
https://pubmed.ncbi.nlm.nih.gov/10511410
https://pubmed.ncbi.nlm.nih.gov/10511410
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 280(3)
AR177 is a 17-mer oligonucleotide that has anti-human immunodeficiency virus activity in vitro. The disposition of internally labeled 33P-AR177 was studied after the tail vein injection of single and multiple doses (0.7 mg/kg) to rats. After a single
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::53462a1b24164163e5f15bcb91f20f76
https://pubmed.ncbi.nlm.nih.gov/9067338
https://pubmed.ncbi.nlm.nih.gov/9067338
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 278(3)
5' GTGGTGGGTGGGTGGGT-3' (AR177) is a 17-mer oligonucleotide with anti-human immunodeficiency virus (HIV) activity that is composed of a phosphodiester backbone and single phosphorothioate linkages at the 3' and 5' ends. A hemodynamic toxicity study w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9310a0fa1558ebe557dbbc33aa462851
https://pubmed.ncbi.nlm.nih.gov/8819516
https://pubmed.ncbi.nlm.nih.gov/8819516
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 278(3)
5'GTGGTGGGTGGGTGGGT-3' (AR177) is a partial phosphorothioate, 17-mer oligonucleotide that has been shown to have anti-human immunodeficiency virus (HIV) activity in vitro and to be a potent inhibitor of HIV-1 integrase. A repeat-dose toxicity and pha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d2b031f6452c7ff0c09613e9d4cf6f17
https://pubmed.ncbi.nlm.nih.gov/8819517
https://pubmed.ncbi.nlm.nih.gov/8819517
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 269(1)
After intradermal administration of 3.7 mg/kg of 14C-labeled 5'-TTGCTTCCATCTTCCTCGTC-3' (14C-labeled ISIS 2105) to rats, a phosphorothioate oligodeoxynucleotide, absorption was rapid. Approximately 65% of the administered dose was absorbed within 1 h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0512a8e79496e18f8babeebea5a802a3
https://pubmed.ncbi.nlm.nih.gov/8169856
https://pubmed.ncbi.nlm.nih.gov/8169856
Autor:
P A, Cossum, H, Sasmor, D, Dellinger, L, Truong, L, Cummins, S R, Owens, P M, Markham, J P, Shea, S, Crooke
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 267(3)
5'-TTGCTTCCATCTTCCTCGTC-3' (ISIS 2105) is a phosphorothioate oligodeoxynucleotide currently being evaluated as an intralesional antiviral drug for the treatment of genital warts that are caused by the human papillomavirus. ISIS 2105, labeled with 14C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bcdc6e6a6fe390e76977e3c3ae779e71
https://pubmed.ncbi.nlm.nih.gov/8166890
https://pubmed.ncbi.nlm.nih.gov/8166890
Publikováno v:
Pharmaceutical research. 9(3)
The pharmacokinetics and tissue distribution of a human relaxin were investigated after intravenous (iv) bolus administration to pregnant or nonpregnant rats. Human gene-2 relaxin (hRlx-2) serum concentrations after iv bolus administration were descr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fb2fd881f4b3e62347bfc6f80d8684ed
https://pubmed.ncbi.nlm.nih.gov/1614978
https://pubmed.ncbi.nlm.nih.gov/1614978
Publikováno v:
The Journal of endocrinology. 130(3)
A synthetic version of the human relaxin encoded by the human gene 2 (hRlx-2) was administered to pregnant rhesus monkeys (Macaca mulatta) on gestational days 141–158. Monkeys (three per group) received doses of 100 μg/kg or 2000 μg/kg as a conti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8dbb540de7b6dda291d1d121a323b5f
https://pubmed.ncbi.nlm.nih.gov/1940712
https://pubmed.ncbi.nlm.nih.gov/1940712
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Akademický článek
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