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Akademický článek

Asthma diagnosis: a comparison of established diagnostic guidelines in adults with respiratory symptomsResearch in context

Autor: Andrew J. Simpson, Sarah Drake, Laura Healy, Ran Wang, Miriam Bennett, Hannah Wardman, Hannah Durrington, Stephen J. Fowler, Clare S. Murray, Angela Simpson

Publikováno v: EClinicalMedicine, Vol 76, Iss , Pp 102813- (2024)

Summary: Background: Considerable variability exists between asthma diagnostic guidelines. We tested the performance characteristics of the European Respiratory Society (ERS), the National Institute for Health and Care Excellence (NICE) and the Globa

Externí odkaz: https://doaj.org/article/bc27e8f21d63459dbaf8d29c488d1e20

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Akademický článek

Endothelial derived, secreted long non-coding RNAs Gadlor1 and Gadlor2 aggravate cardiac remodeling

Publikováno v: Molecular Therapy: Nucleic Acids, Vol 35, Iss 3, Pp 102306- (2024)

Pathological cardiac remodeling predisposes individuals to developing heart failure. Here, we investigated two co-regulated long non-coding RNAs (lncRNAs), termed Gadlor1 and Gadlor2, which are upregulated in failing hearts of patients and mice. Card

Externí odkaz: https://doaj.org/article/35dc9f1f1a1a4ecda9219b0bc2786a74

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Akademický článek

CSF hyperdynamics in rats mimicking the obesity and androgen excess characteristic of patients with idiopathic intracranial hypertension

Autor: Jonathan H. Wardman, Søren Norge Andreassen, Trine L. Toft-Bertelsen, Mette Nyholm Jensen, Jens E. Wilhjelm, Bjarne Styrishave, Steffen Hamann, Steffen Heegaard, Alexandra J. Sinclair, Nanna MacAulay

Publikováno v: Fluids and Barriers of the CNS, Vol 21, Iss 1, Pp 1-20 (2024)

Abstract Background Idiopathic intracranial hypertension (IIH) is a syndrome exhibiting elevated intracranial pressure (ICP), visual disturbances, and severe headache. IIH primarily affects young obese women, though it can occur in individuals of any

Externí odkaz: https://doaj.org/article/5f7a8343575f4f48aa2f4921bab051fa

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Development of a High Fidelity Simulator for Generalised Photometric Based Space Object Classification using Machine Learning

Autor: Allworth, James, Windrim, Lloyd, Wardman, Jeffrey, Kucharski, Daniel, Bennett, James, Bryson, Mitch

Publikováno v: Proceedings of the 70th International Astronautical Congress, 2019

This paper presents the initial stages in the development of a deep learning classifier for generalised Resident Space Object (RSO) characterisation that combines high-fidelity simulated light curves with transfer learning to improve the performance

Externí odkaz: http://arxiv.org/abs/2004.12270

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Akademický článek

Modelling idiopathic intracranial hypertension in rats: contributions of high fat diet and testosterone to intracranial pressure and cerebrospinal fluid production

Autor: Jonathan H. Wardman, Mette N. Jensen, Søren N. Andreassen, Bjarne Styrishave, Jens E. Wilhjelm, Alexandra J. Sinclair, Nanna MacAulay

Publikováno v: Fluids and Barriers of the CNS, Vol 20, Iss 1, Pp 1-17 (2023)

Abstract Background Idiopathic intracranial hypertension (IIH) is a condition characterized by increased intracranial pressure (ICP), impaired vision, and headache. Most cases of IIH occur in obese women of childbearing age, though age, BMI, and fema

Externí odkaz: https://doaj.org/article/0647ec6366f846b1b53a0aac35c79639

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