Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Pınar Kocabaş"'
Autor:
Mattias Uhlen, Shan Huang, Thomas Svensson, Pınar Kocabaş, Jonathan L. Robinson, Mihail Anton, Hao Wang, Johan Gustafsson, Johan Gobom, Pierre-Etienne Cholley, Jens Nielsen, Henrik Zetterberg
Publikováno v:
Wang, H, Robinson, J L, Kocabas, P, Gustafsson, J, Anton, M, Cholley, P-E, Huang, S, Gobom, J, Svensson, T, Uhlen, M, Zetterberg, H & Nielsen, J 2021, ' Genome-scale metabolic network reconstruction of model animals as a platform for translational research ', Proceedings of the National Academy of Sciences of the United States of America, vol. 118, no. 30, e2102344118 . https://doi.org/10.1073/pnas.2102344118
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America
Significance Animal models and genome-scale metabolic models (GEMs) are two important tools for studying human diseases, but a proper integration of the two is lacking. To bridge them, we developed a reproducible and systematic framework by which the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92af6dff02b13d4bad687b44724a9b6a
https://orbit.dtu.dk/en/publications/534c2a92-5e5e-41e7-9d52-ba7c208fe4ae
https://orbit.dtu.dk/en/publications/534c2a92-5e5e-41e7-9d52-ba7c208fe4ae
Autor:
Jonathan L. Robinson, Jens Nielsen, Eduard J. Kerkhoven, Alex Hedin, L. Thomas Svensson, Lena Hansson, Bernhard O. Palsson, Virinchi Billa, Angelo Limeta, Pierre Etienne Cholley, Mathias Uhlén, Avlant Nilsson, Hao Wang, Adil Mardinoglu, Raphael Ferreira, Iván Domenzain, Mihail Anton, Daniel Cook, Pınar Kocabaş, Johan Gustafsson
Publikováno v:
Robinson, J L, Kocabaş, P, Wang, H, Cholley, P E, Cook, D, Nilsson, A, Anton, M, Ferreira, R, Domenzain, I, Billa, V, Limeta, A, Hedin, A, Gustafsson, J, Kerkhoven, E J, Svensson, L T, Palsson, B O, Mardinoglu, A, Hansson, L, Uhlén, M & Nielsen, J 2020, ' An atlas of human metabolism ', Science Signaling, vol. 13, no. 624, eaaz1482 . https://doi.org/10.1126/scisignal.aaz1482
Science signaling, vol 13, iss 624
Sci Signal
Science Signaling
Science signaling, vol 13, iss 624
Sci Signal
Science Signaling
Genome-scale metabolic models (GEMs) are valuable tools to study metabolism and provide a scaffold for the integrative analysis of omics data. Researchers have developed increasingly comprehensive human GEMs, but the disconnect among different model
Publikováno v:
Biochemical Engineering Journal. 127:242-261
Oxygen transfer influences intracellular fluxes which are orchestrated by genome and its transcription in Bacillus subtilis throughout fermentation in recombinant human growth hormone (rhGH) production. Responses of B. subtilis reaction network to ox
Publikováno v:
Biochemical Engineering Journal. 127:229-241
Bacillus subtilis genome-scale model (GEM) reconstruction was stimulated by the recent sequencing and consequent re-annotations. The updated gene-enzyme-reaction data were collected from databases to reconstruct B. subtilis reaction network BsRN-2016
Publikováno v:
Journal of Chemical Technology & Biotechnology. 91:2740-2750
BACKGROUND Design principles of a fed-batch bioreactor system to fine-tune bioreactor performance by increasing production and productivity are investigated. To enhance the production and productivity in fed-batch fermentation of recombinant human gr
Autor:
Gedik, Pınar Kocabaş
Cataloged from PDF version of article. Includes bibliographical references (leaves 101-109). Thesis (M.S.): Bilkent University, The Program of Teaching English as a Foreign Language, İhsan Doğramacı Bilkent University, 2016. This longitudinal, cas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3533::803b29c86b9048196feab14e83e0c060
https://hdl.handle.net/11693/29130
https://hdl.handle.net/11693/29130
Autor:
Güzide Çalık, Özge Deniz Yilmaz, Tunçer H. Özdamar, Pınar Çalık, Pınar Kocabaş, Birgül Şentürk
Publikováno v:
Chemical Engineering Science. 65:574-580
To interpret the effect of human protein gene, e.g., human growth hormone gene hGH, on the intracellular bioreaction network of Bacillus subtilis, the intracellular reaction fluxes were calculated by solving the mass-balance-based genome-scale mathem
Publikováno v:
Enzyme and Microbial Technology. 39:1077-1088
A wild-type thermoacidophilic bacteria Bacillus acidocaldarius which excretes l -tryptophan (Trp) was used for the production of Trp. A fructose-based defined fermentation medium, i.e. containing 8 kg m −3 fructose, 5.0 kg m −3 (NH 4 ) 2 HPO 4 ,
Publikováno v:
Biotechnology journal. 4(7)
This review focuses on the construction of a global, comprehensive understanding of Bacillus subtilis through microarray studies. The microarray studies in B. subtilis were analysed based on the theme of the work, by mentioning the growth media, bior