Lessons from more than 80 structures of the GluA2 ligand-binding domain in complex with agonists, antagonists and allosteric modulators

Autor: Pøhlsgaard, Jacob, Frydenvang, Karla, Madsen, Ulf, Kastrup, Jette Sandholm

Publikováno v: In Neuropharmacology 2011 60(1):135-150

Single 23S rRNA mutations at the ribosomal peptidyl transferase centre confer resistance to valnemulin and other antibiotics in Mycobacterium smegmatis by perturbation of the drug binding pocket

Autor: Long, Katherine S., Pøhlsgaard, Jacob, Hansen, Lykke Haastrup, Hobbie, Sven N., Böttger, Erik C., Vester, Birte

Publikováno v: Long, K S, Pøhlsgaard, J, Hansen, L H, Hobbie, S N, Böttger, E C & Vester, B 2009, ' Single 23S rRNA mutations at the ribosomal peptidyl transferase centre confer resistance to valnemulin and other antibiotics in Mycobacterium smegmatis by perturbation of the drug binding pocket ', Molecular Microbiology, vol. 71, no. 5, pp. 1218-1227 .

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3062::765db93bb0208523bf4b74b65fc25f4b
https://portal.findresearcher.sdu.dk/da/publications/615e81d0-6bc0-11de-9c46-000ea68e967b

The structural basis of macrolide-ribosome binding assessed using mutagenesis of rRNA positions A2058 and A2059

Autor: Pfister, P., Pøhlsgaard, Jacob, Thomas, A., Douthwaite, Stephen Roger, Ban, N., Böttger, E.C.

Publikováno v: Pfister, P, Pøhlsgaard, J, Thomas, A, Douthwaite, S R, Ban, N & Böttger, E C 2004, ' The structural basis of macrolide-ribosome binding assessed using mutagenesis of rRNA positions A2058 and A2059. ', Journal of Molecular Biology, vol. 342, pp. 1569-1581 . https://doi.org/10.1016/j.jmb.2004.07.095

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3062::c592e509f4edf80c87f51fbff7bf47bf
https://portal.findresearcher.sdu.dk/da/publications/690ade70-f196-11db-821c-000ea68e967b

Design, synthesis and ribosome binding of chloramphenicol nucleotide and intercalator conjugates

Autor: Johansson, Dorte, Jessen, Carsten H., Pøhlsgaard, Jacob, Jensen, Kenneth B., Vester, Birte, Pedersen, Erik B., Nielsen, Poul

Publikováno v: In Bioorganic & Medicinal Chemistry Letters 2005 15(8):2079-2083