Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Pía Loren"'
miR-6805-5p as a biomarker of cisplatin-induced nephrotoxicity in patients with head and neck cancer
Autor:
Nadine De Godoy Torso, Julia Coelho França Quintanilha, Maria Aparecida Cursino, Eder De Carvalho Pincinato, Pía Loren, Luis A. Salazar, Carmen Silvia Passos Lima, Patricia Moriel
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction: The standard treatment for head and neck squamous cell carcinoma (HNSCC) is cisplatin chemoradiotherapy. One of the main treatment adverse reactions is nephrotoxicity, for which there is currently no adequate specific and sensitive biom
Externí odkaz:
https://doaj.org/article/fcc0f7205008481798115b390de8badc
Publikováno v:
Biomedicines, Vol 11, Iss 3, p 742 (2023)
Statins are currently the treatment of choice for hypercholesterolemia. However, wide interindividual variability has been observed in the response to treatment. Recent studies have reported the role of lncRNAs in the metabolism of lipids; neverthele
Externí odkaz:
https://doaj.org/article/5e2143f9ddfa4b44a7a97f6c204c01f5
Autor:
Pía Loren, Nicolás Saavedra, Kathleen Saavedra, Nadine De Godoy Torso, Marília Berlofa Visacri, Patricia Moriel, Luis A. Salazar
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Cisplatin (DDP) is a well-known anticancer drug used for the treatment of numerous human cancers in solid organs, including bladder, breast, cervical, head and neck squamous cell, ovarian, among others. Its most important mode of action is the DNA-pl
Externí odkaz:
https://doaj.org/article/8fa2c4a7244f48899e04a8168013ffcb
Publikováno v:
Biomolecules, Vol 12, Iss 10, p 1365 (2022)
Cisplatin (CDDP) is the drug of choice against different types of cancer. However, tumor cells can acquire resistance to the damage caused by cisplatin, generating genetic and epigenetic changes that lead to the generation of resistance and the activ
Externí odkaz:
https://doaj.org/article/35ad18ee46bd456ab35c63d98500fa87
Autor:
Pía Loren, Yuliannis Lugones, Nicolás Saavedra, Kathleen Saavedra, Isis Páez, Nelia Rodriguez, Patricia Moriel, Luis A. Salazar
Publikováno v:
Biomolecules, Vol 12, Iss 9, p 1206 (2022)
Cisplatin (cis-diamminedichloroplatinum (II), DDP) is an antineoplastic agent widely used in the treatment of solid tumors because of its extensive cytotoxic activity. However, the main limiting side effect of DDP use is nephrotoxicity, a rapid deter
Externí odkaz:
https://doaj.org/article/a31020eba7b7417db045dc2af4ce4834
Autor:
Pía Loren, Nicolás Saavedra, Kathleen Saavedra, Tomás Zambrano, Patricia Moriel, Luis A. Salazar
Publikováno v:
Pharmaceuticals, Vol 14, Iss 6, p 491 (2021)
Cisplatin is an antineoplastic drug used for the treatment of many solid tumors. Among its various side effects, nephrotoxicity is the most detrimental. In recent years, epigenetic regulation has emerged as a modulatory mechanism of cisplatin-induced
Externí odkaz:
https://doaj.org/article/8a6b61fce50f4c0381054fdd45cb0928
Autor:
Aline de Souza Nicoletti, Luis A. Salazar, Eder de Carvalho Pincinato, Nicolás Saavedra, Kathleen Saavedra, Pía Loren, Marília Berlofa Visacri, Patricia Moriel
Publikováno v:
Biomarkers in Medicine
Aim: miRNAs are potential biomarkers of several diseases. This review aimed to identify the miRNAs that could serve as biomarkers of COVID-19. Materials & methods: A literature search of nine databases was carried out for studies published before 13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5369f07c6f28013ea3f53f95bc048f47
https://pubmed.ncbi.nlm.nih.gov/34784802
https://pubmed.ncbi.nlm.nih.gov/34784802
Autor:
João Kleber Novais Pereira, Marília Berlofa Visacri, Nicolás Saavedra, Kathleen Saavedra, Nadine de Godoy Torso, Pedro Eduardo Nascimento Silva Vasconcelos, Luis A. Salazar, Pía Loren, Patricia Moriel
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 12765, p 12765 (2021)
International Journal of Molecular Sciences, Vol 22, Iss 12765, p 12765 (2021)
The purpose of this systematic review was to map out and summarize scientific evidence on dysregulated microRNAs (miRNAs) that can be possible biomarkers or therapeutic targets for cisplatin nephrotoxicity and have already been tested in humans, anim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dafbc31d5e4e4b400e8fe8045b3a14a5
https://pubmed.ncbi.nlm.nih.gov/34884570
https://pubmed.ncbi.nlm.nih.gov/34884570
Autor:
Nicolás Saavedra, Kathleen Saavedra, Pía Loren, Luis A. Salazar, Tomás Zambrano, Patricia Moriel
Publikováno v:
Pharmaceuticals, Vol 14, Iss 491, p 491 (2021)
Pharmaceuticals
Pharmaceuticals
Cisplatin is an antineoplastic drug used for the treatment of many solid tumors. Among its various side effects, nephrotoxicity is the most detrimental. In recent years, epigenetic regulation has emerged as a modulatory mechanism of cisplatin-induced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d8201122f78d0d335f7838486f1a4d9
https://www.mdpi.com/1424-8247/14/6/491
https://www.mdpi.com/1424-8247/14/6/491
Autor:
Esther Sánchez-Villalba, Pía Loren, Ricardo Felmer, Raúl Sánchez, M. E. Arias, Jennie Risopatrón
Publikováno v:
Animal reproduction science. 219
Short-term treatment of mammalian oocytes with different stressors induces stress tolerance of embryos derived from these oocytes. The aims of this study were to evaluate effects on embryo development when there was treatment of oocyte complexes (COC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c336207af1176e2181657809482d86a7
https://pubmed.ncbi.nlm.nih.gov/32828397
https://pubmed.ncbi.nlm.nih.gov/32828397