Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Péter Krajcsi"'
Publikováno v:
Pharmaceutics, Vol 15, Iss 1, p 29 (2022)
Bile acids and bile salts (BA/BS) are substrates of both influx and efflux transporters on hepatocytes. Canalicular efflux transporters, such as BSEP and MRP2, are crucial for the removal of BA/BS to the bile. Basolateral influx transporters, such as
Externí odkaz:
https://doaj.org/article/a22e6b8f5dc94923b473eb9e8b6cec34
Publikováno v:
Pharmaceutics, Vol 13, Iss 6, p 899 (2021)
Background: Serum urate (SU) levels in primates are extraordinarily high among mammals. Urate is a Janus-faced molecule that acts physiologically as a protective antioxidant but provokes inflammation and gout when it precipitates at high concentratio
Externí odkaz:
https://doaj.org/article/e980c88b06d54b2087de909018b830b6
Autor:
Franciska Erdő, Péter Krajcsi
Publikováno v:
Frontiers in Aging Neuroscience, Vol 11 (2019)
During the last decade, several articles have reported a relationship between advanced age and changes in the integrity of the blood-brain barrier (BBB). These changes were manifested not only in the morphology and structure of the cerebral microvess
Externí odkaz:
https://doaj.org/article/d3ba3c5c238c4eb38f76e04d9e42a0b3
Autor:
Péter Tátrai, Péter Krajcsi
Publikováno v:
Pharmaceutics, Vol 12, Iss 8, p 755 (2020)
Bilirubin, the end product of heme catabolism, is produced continuously in the body and may reach toxic levels if accumulates in the serum and tissues; therefore, a highly efficient mechanism evolved for its disposition. Normally, unconjugated biliru
Externí odkaz:
https://doaj.org/article/d89ce57255ab4a87816984ee558609cc
Autor:
Bernadett, Kalapos-Kovács, Viktória, Juhász, Csilla, Temesszentandrási-Ambrus, Balázs, Magda, Pál T, Szabó, István, Antal, Imre, Klebovich, Péter, Krajcsi
Publikováno v:
Phytotherapy research : PTR. 32(8)
The use and significance of baicalin, the main bioactive component found in Radix Scutellaria, have been on the rise due to its interesting pharmacological properties. Baicalin, a low passive permeability compound, is directly absorbed from the upper
Autor:
Bernadett, Kalapos-Kovács, Balázs, Magda, Márton, Jani, Zsolt, Fekete, Pál T, Szabó, István, Antal, Péter, Krajcsi, Imre, Klebovich
Publikováno v:
Phytotherapy research : PTR. 29(12)
Baicalein, the aglycone formed by hydrolysis of baicalin in the intestine, is well absorbed by passive diffusion but subjected to extensive intestinal glucuronidation. Efflux of baicalin, the low passive permeability glucuronide of baicalein from ent
Autor:
Angela Aliberti, Patrick Allard, Arturo Anadón, Vellareddy Anantharam, Anthony E. Archibong, Adam D. Aulbach, Aryamitra Banerjee, Leah D. Banks, Frank A. Barile, Sudheer R. Beedanagari, Enrico Bergamaschi, Sneha P. Bhatia, Karyn Bischoff, Víctor Castellano, Daniel T. Chang, James J. Chen, Deborah Citrin, Rory Conolly, R.W. Coppock, Lucio G. Costa, T.V. Damodaran, Kellye K. Daniels, Curtis C. Dary, Robin B. Doss, Filipe V. Duarte, Margitta M. Dziwenka, Stephen Edwards, Jorge Estévez, Daniel S. Fabricant, Anna M. Fan, Ali Faqi, Suzanne E. Fenton, Vanessa A Fitsanakis, John Flaskos, Swaran J.S. Flora, Sue M. Ford, Domniki Fragou, Shayne C. Gad, Niels-Christian Ganderup, Dale R. Gardner, Ronette Gehring, Fernando Gil, Saryu Goel, Michael-Rock Goldsmith, Christopher M. Grulke, Mary Gulumian, P.K. Gupta, Ramesh C. Gupta, Sharon Gwaltney-Brant, Alan J Hargreaves, Kelly L. Harris, Holly E. Hatfield, Diane E. Heck, Antonio F. Hernández, Corey J. Hilmas, Evangelia Hondroulis, Darryl B. Hood, Kathryn Hudak, Pasi Huuskonen, Stewart B. Jacobson, Huajun Jin, Laurie B. Joseph, Jun Kanno, Anumantha G. Kanthasamy, Arthi Kanthasamy, Navinchandra M. Kaore, Shilpa N. Kaore, Bhupendra S. Kaphalia, Vesa Karttunen, Greer E. Kaufman, Ravneet Kaur, Hong Duck Kim, Prasada Rao S. Kodavanti, Urmila P. Kodavanti, George A. Kontadakis, Péter Krajcsi, Gopala Krishna, Kavya A. Krishna, Maria Kummu, George D. Kymionis, Michelle A. Lasher, Chen-zhong Li, Wei-Jiun Lin, Bommanna G. Loganathan, Jarkko Loikkanen, Anna E. Lokshin, Marcello Lotti, Tzu-Pin Lu, Yi Lu, Chikezie Madu, Rémi Magnan, Brinda Mahadevan, Jane A. Mantey, María Rosa Martínez-Larrañaga, Vincent P. Meador, Dejan Milatovic, Pushpinder K. Multani, Päivi Myllynen, Kirsi Myöhänen, Rekek Negga, Jairo Nelson, Brian M. Nolen, Meliton N. Novilla, Stephanie Padilla, Carlos M. Palmeira, Kip E. Panter, Markku Pasanen, Daniel J. Patrick, Sofia Pavanello, Olavi Pelkonen, Claudia Pellacani, Michael A. Pellizzon, Andrew D. Penman, Martin Phillips, Jason Pitt, Argyro Plaka, Aramandla Ramesh, Kausik Ray, Casey E. Reed, Jenni Repo, Matthew R. Ricci, Anabela P. Rolo, Magdalini Sachana, Heidi Sahlman, Nitin Saini, William F. Salminen, Kai Savolainen, Laura K. Schnackenberg, D.T. Selvam, Praveen Sharma, Qiang Shi, Elina Sieppi, Jon Sobus, Miguel A. Sogorb, Melissa Stick, Markus Storvik, David T. Szabo, Yu-Mei Tan, João S. Teodoro, Rogelio Tornero-Velez, Beáta Toth, Aristides M. Tsatsakis, Kirsi Vähäkangas, Deon van der Merwe, Ana T. Varela, Eugenio Vilanova, Suryanarayana V. Vulimiri, Kevin D. Welch, Xi Yang, Snjezana Zaja-Milatovic, Csaba K. Zoltani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e252fcbbe40cb0fd666a060a268dd861
https://doi.org/10.1016/b978-0-12-404630-6.00070-1
https://doi.org/10.1016/b978-0-12-404630-6.00070-1
Autor:
Pierre Fraikin, Bernard Pirotte, Dominique Heymann, László G. Puskás, Thomas H. Lubben, Luca Munaron, C. Philippe, Susanna Antoniotti, Haim J. Wolfson, Zsolt Lo\\'rincz, Barbara Malawska, Antal Simay, C. Garcia-Echeverria, Péter Mátyus, Alessandra Fiorio Pla, Ruth Nussinov, Marcin Gruchala, Peter J. Scammells, Martin Eggert, Szilvia Vajda, Gurbir S. Bhatia, András Varró, Bruce G. Szczepankiewicz, Panagiotis Zoumpoulakis, Ildikó Varga, Mark S. Levi, Jerry Ryan Holder, Péter Krajcsi, Margaret A. Brimble, László Ürge, Thomas Mavromoustakos, Nastiti Wijayanti, William A. Banks, William H. Bunnelle, Zhonghua Pei, Krista R. Wilson, Paola Zaccone, David W. Dunne, O.M. Zack Howard, Tomozumi Imamichi, Gregory Y.H. Lip, Christine G. Joseph, Carrie Haskell-Luevano, Maria Zervou, R. Efremov, Ákos Kocsis, G.B. Mahady, Tingjun Hou, Marcel J. de Groot, David R. Davies, Thomas D.C. Thomas, Michael R. Schrimpf, Allen B. Reitz, Stewart B. Kirton, Boman G. Irani, Seppo Ylä-Herttuala, Xiaojie Xu, Zoltán Kovári, Uwe K. Zettl, Gang Liu, Andreas Klüter, Tivadar Rettegi, Rebecca Deprez-Poulain, Péter Kovács, László Károlyházy, Dimitra Hadjipavlou-Litina, Kuo-Chen Chou, Benoit Deprez, Ferenc Darvas, Mark Levis, Donald Small, M. Iqbal Choudhary, Thang K. Chiu, Julius Gy. Papp, Michael J. Dart, Pascal de Tullio, Atta-ur-Rahman, Andrzej Wilczynski, György Dormán, Himadri Roy, Russell C. Davis, C. Bor-Luen, Stephan Immenschuh, Michael D. Sosin, Alexandra Shulman-Peleg, Anne Cooke, Davide Lovisolo, Michael J. Sutcliffe, Dina Schneidman-Duhovny, Oranit Dror, Gunther Neeck, Aleksandar Todorovic, István Pénzes, Shalini Bhardwaj, Sally A. Hutchinson, P.R. Bernstein, Pierre Francotte, Cheryl P. Kordik, David A. Jans
Publikováno v:
Frontiers in Medicinal Chemistry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f72de8108bc0fb8e384ae8a8f7537eb
https://doi.org/10.2174/97816080546401130601
https://doi.org/10.2174/97816080546401130601
Autor:
Akos, Pál, Emese, Kis, Dóra, Méhn, Hristos, Glavinas, Tünde, Nagy, Péter, Mészaros, György, Báthori, Péter, Krajcsi, György, Falkay
Publikováno v:
Acta pharmaceutica Hungarica. 77(4)
ABCG2, a transporter of the ATP-binding cassette family, is known to play a prominent role in the absorption, distribution, metabolism, and excretion of xenobiotics. Drug-transporter interactions are commonly screened by in vitro systems using transf
Publikováno v:
Chirality. 14(8)
The binding of bimoclomol enantiomers to human plasma, its components, as well as to plasma from monkey, dog, rat, and mouse was investigated by ultrafiltration and equilibrium dialysis. The considerably stronger binding of the (-)-(S)-enantiomer fou