Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Péter Bánhegyi"'
Autor:
Boglárka Kántás, Éva Szőke, Rita Börzsei, Péter Bánhegyi, Junaid Asghar, Lina Hudhud, Anita Steib, Ágnes Hunyady, Ádám Horváth, Angéla Kecskés, Éva Borbély, Csaba Hetényi, Gábor Pethő, Erika Pintér, Zsuzsanna Helyes
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2021)
Background: Somatostatin released from the capsaicin-sensitive sensory nerves mediates analgesic and anti-inflammatory effects via its receptor subtype 4 (SST4) without influencing endocrine functions. Therefore, SST4 is considered to be a novel targ
Externí odkaz:
https://doaj.org/article/9adb7364d2ac44c6a60eb936e1d9b20a
Autor:
Csilla Temesszentandrási-Ambrus, Szilárd Tóth, Rinkee Verma, Péter Bánhegyi, István Szabadkai, Ferenc Baska, Csaba Szántai-Kis, Ruben C Hartkoorn, Mary A Lingerfelt, Balázs Sarkadi, Gergely Szakács, László Őrfi, Valakunja Nagaraja, Sean Ekins, Ágnes Telbisz
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0202749 (2018)
Drug resistant tuberculosis (TB) is a major worldwide health problem. In addition to the bacterial mechanisms, human drug transporters limiting the cellular accumulation and the pharmacological disposition of drugs also influence the efficacy of trea
Externí odkaz:
https://doaj.org/article/1a845305b8a4467da0d15ebe921cc693
Autor:
Sándor Boros, Marcell Krekó, Péter Markó, László Őrfi, Eszter Illyés, Péter Bánhegyi, Bálint Szokol, István Szabadkai, Zsófia Czudor, Csaba Szántai-Kis, Diána Brauswetter, Pál Gyulavári, Attila Varga
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 28:3265-3270
Aurora kinases as regulators of cell division have become promising therapeutic targets recently. Here we report novel, low molecular weight benzothiophene-3-carboxamide derivatives designed and optimized for inhibiting Aurora kinases. The most effec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7fa476753e61abf862f94dc70e6833b
https://doi.org/10.1016/j.bmcl.2018.05.064
https://doi.org/10.1016/j.bmcl.2018.05.064
Autor:
Péter Bánhegyi, László Őrfi, Zoltán Horváth, Csaba Szántai-Kis, Mária Balogh, Bálint Szokol, Zsófia Czudor, Eszter Illyés, Judit Dobos, Márk Fábián, Nóra Breza, Sándor Boros, Anna Sipos, Péter Markó
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 28:769-773
Cyclin-dependent kinases (CDKs) and Polo-like kinases (PLKs) play key role in the regulation of the cell cycle. The aim of our study was originally the further development of our recently discovered polo-like kinase 1 (PLK1) inhibitors. A series of n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47c0139cad5407f466b20ae41d91c700
https://doi.org/10.1016/j.bmcl.2018.01.002
https://doi.org/10.1016/j.bmcl.2018.01.002
Autor:
Ágnes Hunyady, Ádám Horváth, Boglárka Kántás, Csaba Hetényi, Éva Borbély, Erika Pintér, Péter Bánhegyi, Éva Szőke, Rita Börzsei, Zsuzsanna Helyes
Publikováno v:
International Journal of Molecular Sciences
Volume 20
Issue 24
Volume 20
Issue 24
Somatostatin released from the capsaicin-sensitive sensory nerves mediates analgesic and anti-inflammatory effects via the somatostatin sst4 receptor without endocrine actions. Therefore, sst4 is considered to be a novel target for drug development i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23eea4ca1bf8c1ae66d8da62657044e4
Autor:
Péter Bánhegyi, Zoltán Greff, Axel Ullrich, Tibor Vántus, László Őrfi, József Mandl, György Kéri, Laura Simon-Szabó, Csaba Szántai-Kis, Sándor Boros, Márton Kokas, Lilian Zsákai, Miklós Csala, Gábor Bánhegyi, István Vályi-Nagy
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 26:424-428
Activation of various interacting stress kinases, particularly the c-Jun N-terminal kinases (JNK), and a concomitant phosphorylation of insulin receptor substrate 1 (IRS-1) at serine 307 play a central role both in insulin resistance and in β-cell d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e6a1a75d264d9775c6078b36286ed7b
https://doi.org/10.1016/j.bmcl.2015.11.099
https://doi.org/10.1016/j.bmcl.2015.11.099
Autor:
Péter Bánhegyi, István Szabadkai, Szilárd Tóth, Valakunja Nagaraja, Ágnes Telbisz, Csilla Temesszentandrási-Ambrus, Ferenc Baska, Sean Ekins, Balázs Sarkadi, Ruben C. Hartkoorn, László Őrfi, Csaba Szántai-Kis, Rinkee Verma, Gergely Szakács, Mary A. Lingerfelt
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0202749 (2018)
Drug resistant tuberculosis (TB) is a major worldwide health problem. In addition to the bacterial mechanisms, human drug transporters limiting the cellular accumulation and the pharmacological disposition of drugs also influence the efficacy of trea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc239647ac4a83842bdd378514c8a029
https://igi.indrastra.com/items/show/190766
https://igi.indrastra.com/items/show/190766
Autor:
György Kéri, Zoltán Greff, Doris Hafenbradl, György Mészáros, M. Ko, Laszlo Orfi, Yossef Av-Gay, Csaba Szántai-Kis, Róbert Gábor Kiss, János Pató, S. Perozzi, Bert Klebl, R. Szekely, Péter Bánhegyi, Zoltán Horváth, Silvia Garavaglia, D. Eros, Gabor Borbely, Gábor Németh, Zoltán Varga, Menico Rizzi, Jenö Marosfalvi, Nóra Breza, Bálint Hegymegi-Barakonyi
Publikováno v:
Current Medicinal Chemistry. 15:2760-2770
Tuberculosis causes nearly two million deaths per year world-wide. In addition multidrug-resistant mycobacterial strains rapidly emerge so novel therapeutic approaches are needed. Recently, several promising mycobacterial target molecules were identi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5509b4be3f118bff74fae83b3fd6f53
https://doi.org/10.2174/092986708786242886
https://doi.org/10.2174/092986708786242886
Autor:
Gabor Borbely, János Pató, Péter Bánhegyi, Nóra Breza, Bálint Hegymegi-Barakonyi, Edit Várkondi, Laszlo Orfi, István Peták, György Kéri
Publikováno v:
Journal of Receptors and Signal Transduction. 28:361-373
The development of selective protein kinase inhibitors has become an important area of drug discovery for the treatment of different diseases. We report the synthesis and characterization of a series of novel quinazoline derivatives against three the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6188eac2eac81cd72b292673f9230aa9
https://doi.org/10.1080/10799890802242618
https://doi.org/10.1080/10799890802242618
Autor:
Ferenc, Baska, Edina Rita, Székely, Csaba, Szántai-Kis, Péter, Bánhegyi, Bálint, Hegymegi-Barakonyi, Gábor, Németh, Nóra, Breza, Lilian, Zsákai, Zoltán, Greff, János, Pató, György, Kéri, Lászlo, Orfi
Publikováno v:
Acta pharmaceutica Hungarica. 83(3)
Tuberculosis is considered to be one of the major health problem not only in the less developed countries but in the economically developed countries as well. Roughly one third of the world's population are infected with Mycobacterium tuberculosis an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::afe7359df097c1c437586c543101150b
https://pubmed.ncbi.nlm.nih.gov/24369587
https://pubmed.ncbi.nlm.nih.gov/24369587