Zobrazeno 1 - 10 of 104 pro vyhledávání: '"Pérez Simó G"'
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Akademický článek
Impact of Molecular Testing Using Next-Generation Sequencing in the Clinical Management of Patients with Non-Small Cell Lung Cancer in a Public Healthcare Hospital.
Autor: Simarro J; Molecular Biology Unit, Service of Clinical Analysis, Hospital Universitario y Politécnico La Fe, 46026 Valencia, Spain.; Clinical and Translational Cancer Research Group, Instituto de Investigación Sanitaria La Fe (IIS La Fe), 46026 Valencia, Spain., Pérez-Simó G; Molecular Biology Unit, Service of Clinical Analysis, Hospital Universitario y Politécnico La Fe, 46026 Valencia, Spain.; Clinical and Translational Cancer Research Group, Instituto de Investigación Sanitaria La Fe (IIS La Fe), 46026 Valencia, Spain., Mancheño N; Pathology Department, Hospital Universitario y Politécnico La Fe, 46026 Valencia, Spain., Ansotegui E; Pulmonology Department, Hospital Universitario y Politécnico La Fe, 46026 Valencia, Spain., Muñoz-Núñez CF; Radiology Department, Hospital Universitario y Politécnico La Fe, 46026 Valencia, Spain., Gómez-Codina J; Clinical and Translational Cancer Research Group, Instituto de Investigación Sanitaria La Fe (IIS La Fe), 46026 Valencia, Spain.; Medical Oncology Department, Hospital Universitario y Politécnico La Fe, 46026 Valencia, Spain., Juan Ó; Medical Oncology Department, Hospital Universitario y Politécnico La Fe, 46026 Valencia, Spain., Palanca S; Molecular Biology Unit, Service of Clinical Analysis, Hospital Universitario y Politécnico La Fe, 46026 Valencia, Spain.; Clinical and Translational Cancer Research Group, Instituto de Investigación Sanitaria La Fe (IIS La Fe), 46026 Valencia, Spain.; Biochemistry and Molecular Biology Department, Universidad de Valencia, 46010 Valencia, Spain.
Publikováno v: Cancers [Cancers (Basel)] 2023 Mar 10; Vol. 15 (6). Date of Electronic Publication: 2023 Mar 10.
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3
Akademický článek
MicroRNAs expression associated with aggressive clinicopathological features and poor prognosis in primary cutaneous melanomas.
Autor: Murria Estal R; Molecular Biology Laboratory, Service of Clinical Analysis, Hospital Universitari i Politecnic La Fe, Valencia, Spain., de Unamuno Bustos B; Molecular Biology Laboratory, Service of Clinical Analysis, Hospital Universitari i Politecnic La Fe, Valencia, Spain., Pérez Simó G; Molecular Biology Laboratory, Service of Clinical Analysis, Hospital Universitari i Politecnic La Fe, Valencia, Spain., Simarro Farinos J; Molecular Biology Laboratory, Service of Clinical Analysis, Hospital Universitari i Politecnic La Fe, Valencia, Spain., Torres Navarro I; Department of Dermatology, Hospital Universitari i Politecnic La Fe, Valencia, Spain., Alegre de Miquel V; Department of Dermatology, Hospital General Universitario de Valencia, Valencia, Spain., Ballester Sánchez R; Department of Dermatology, La Plana Hospital, Villarreal, Castellón, Spain., Sabater Marco V; Department of Pathology, Hospital General Universitario de Valencia, Valencia, Spain., Llavador Ros M; Department of Pathology, Hospital Universitari i Politecnic La Fe, Valencia, Spain., Palanca Suela S; Molecular Biology Laboratory, Service of Clinical Analysis, Hospital Universitari i Politecnic La Fe, Valencia, Spain., Botella Estrada R; Department of Dermatology, Hospital Universitari i Politecnic La Fe, Valencia, Spain.; Department of Medicine, School of Medicine, Universitat de València, Valencia, Spain.
Publikováno v: Melanoma research [Melanoma Res] 2021 Feb 01; Vol. 31 (1), pp. 18-26.
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4
MiR-138-5p Suppresses Cell Growth and Migration in Melanoma by Targeting Telomerase Reverse Transcriptase
Autor: Tarazón E, De Unamuno Bustos B, Murria Estal R, Pérez Simó G, Sahuquillo Torralba A, Simarro J, Palanca Suela S, Botella Estrada R
Publikováno v: Genes
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
Recent evidence suggests the existence of a miRNA regulatory network involving human telomerase reverse transcriptase gene (hTERT), with miR-138-5p playing a central role in many types of cancers. However, little is known about the regulation of hTER
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::f4dc2f6006125169b533ffd1eb7826c9
https://fundanet.iislafe.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=15416
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5
Akademický článek
Technical Validation and Clinical Implications of Ultrasensitive PCR Approaches for EGFR -Thr790Met Mutation Detection in Pretreatment FFPE Samples and in Liquid Biopsies from Non-Small Cell Lung Cancer Patients.
Autor: Simarro J; Molecular Biology Unit, Service of Clinical Analysis, Hospital Universitario y Politécnico La Fe, 46026 Valencia, Spain.; Clinical and Translational Cancer Research Group, Instituto de Investigación Sanitaria La Fe (IIS La Fe), 46026 Valencia, Spain., Pérez-Simó G; Molecular Biology Unit, Service of Clinical Analysis, Hospital Universitario y Politécnico La Fe, 46026 Valencia, Spain.; Clinical and Translational Cancer Research Group, Instituto de Investigación Sanitaria La Fe (IIS La Fe), 46026 Valencia, Spain., Mancheño N; Pathology Department, Hospital Universitario y Politécnico La Fe, 46026 Valencia, Spain., Ansotegui E; Pulmonology Department, Hospital Universitario y Politécnico La Fe, 46026 Valencia, Spain., Muñoz-Núñez CF; Radiology Department, Hospital Universitario y Politécnico La Fe, 46026 Valencia, Spain., Gómez-Codina J; Medical Oncology Department, Hospital Universitario y Politécnico La Fe, 46026 Valencia, Spain., Juan Ó; Medical Oncology Department, Hospital Universitario y Politécnico La Fe, 46026 Valencia, Spain., Palanca S; Molecular Biology Unit, Service of Clinical Analysis, Hospital Universitario y Politécnico La Fe, 46026 Valencia, Spain.; Clinical and Translational Cancer Research Group, Instituto de Investigación Sanitaria La Fe (IIS La Fe), 46026 Valencia, Spain.; Biochemistry and Molecular Biology Department, Universidad de Valencia, 46010 Valencia, Spain.
Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2022 Jul 31; Vol. 23 (15). Date of Electronic Publication: 2022 Jul 31.
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6
Report
Utility of Next-Generation Sequencing in the Reconstruction of Clonal Architecture in a Patient with an EGFR Mutated Advanced Non-Small Cell Lung Cancer: A Case Report.
Autor: Simarro J; Molecular Biology Unit, Service of Clinical Analysis, Hospital Universitario y Politécnico La Fe, 46026 Valencia, Spain.; Clinical and Translational Cancer Research Group, Instituto de Investigación Sanitaria La Fe (IIS La Fe), 46026 Valencia, Spain., Pérez-Simó G; Molecular Biology Unit, Service of Clinical Analysis, Hospital Universitario y Politécnico La Fe, 46026 Valencia, Spain.; Clinical and Translational Cancer Research Group, Instituto de Investigación Sanitaria La Fe (IIS La Fe), 46026 Valencia, Spain., Mancheño N; Pathology Department, Hospital Universitario y Politécnico La Fe, 46026 Valencia, Spain., Muñoz-Núñez CF; Radiology Department, Hospital Universitario y Politécnico La Fe, 46026 Valencia, Spain., Cases E; Pulmonology Department, Hospital Universitario y Politécnico La Fe, 46026 Valencia, Spain., Juan Ó; Medical Oncology Department, Hospital Universitario y Politécnico La Fe, 46026 Valencia, Spain., Palanca S; Molecular Biology Unit, Service of Clinical Analysis, Hospital Universitario y Politécnico La Fe, 46026 Valencia, Spain.; Clinical and Translational Cancer Research Group, Instituto de Investigación Sanitaria La Fe (IIS La Fe), 46026 Valencia, Spain.; Biochemistry and Molecular Biology Department, Universidad de Valencia, Burjassot, 46100 Valencia, Spain.
Publikováno v: Diagnostics (Basel, Switzerland) [Diagnostics (Basel)] 2022 May 19; Vol. 12 (5). Date of Electronic Publication: 2022 May 19.
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7
Telomerase Expression in a Series of Melanocytic Neoplasms
Autor: Moles Poveda P, Llavador Ros M, Palanca Suela S, Botella Estrada R, Sahuquillo Torralba A, Simarro Farinos J, De Unamuno Bustos B, Pérez Simó G
Publikováno v: Actas dermo-sifiliograficas. 110(3)
Background and objectives Telomerase is an enzyme involved in maintaining the length of telomeres and cell senescence. Numerous studies have shown that in more than 90% of malignant tumors telomerase activity is detected. Material and methods Retrosp
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1d5809f806041a3d2b630caa4ed050f
https://pubmed.ncbi.nlm.nih.gov/30591199
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8
Towards Personalized Medicine in Melanoma: Implementation of a Clinical Next-Generation Sequencing Panel
Autor: de Unamuno Bustos B, Murria Estal R, Pérez Simó G, de Juan Jimenez I, Escutia Muñoz B, Rodríguez Serna M, Alegre de Miquel V, Llavador Ros M, Ballester Sánchez R, Nagore Enguídanos E, Palanca Suela S, Botella Estrada R
Publikováno v: SCIENTIFIC REPORTS
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
Molecular diagnostics are increasingly performed routinely in the diagnosis and management of patients with melanoma due to the development of novel therapies that target specific genetic mutations. The development of next-generation sequencing (NGS)
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::41947a711c9c412b7ff2a101fdcd117a
https://fundanet.iislafe.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=7302
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10
Relationship of immunohistochemistry, copy number aberrations and epigenetic disorders with BRCAness pattern in hereditary and sporadic breast cancer
Autor: Murria Estal R, Palanca Suela S, de Juan Jiménez I, Alenda Gonzalez C, Egoavil Rojas C, García-Casado Z, López Guerrero JA, Juan Fita MJ, Sánchez Heras AB, Segura Huerta Á, Santaballa Bertrán A, Chirivella González I, Llop García M, Pérez Simó G, Barragán González E, Bolufer Gilabert P
Publikováno v: FAMILIAL CANCER
r-FISABIO: Repositorio Institucional de Producción Científica
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
r-FISABIO. Repositorio Institucional de Producción Científica
instname
r-ISABIAL. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica y Sanitaria de Alicante
The study aims to identify the relevance of immunohistochemistry (IHC), copy number aberrations (CNA) and epigenetic disorders in BRCAness breast cancers (BCs). We studied 95 paraffin included BCs, of which 41 carried BRCA1/BRCA2 germline mutations a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::3486a12923b0c8cb0f8abb58cadeaab4
https://fundanet.fisabio.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=4594
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