Light-Induced Orthogonal Fragmentation of Crosslinked Peptides.

Autor: Kolbowski L; Chair of Bioanalytics, Technische Universität Berlin, 10623 Berlin, Germany., Belsom A; Chair of Bioanalytics, Technische Universität Berlin, 10623 Berlin, Germany., Pérez-López AM; Chair of Bioanalytics, Technische Universität Berlin, 10623 Berlin, Germany., Ly T; Wellcome Centre for Cell Biology, University of Edinburgh, Edinburgh EH9 3BF, U.K., Rappsilber J; Chair of Bioanalytics, Technische Universität Berlin, 10623 Berlin, Germany.; Wellcome Centre for Cell Biology, University of Edinburgh, Edinburgh EH9 3BF, U.K.; Si-M/″Der Simulierte Mensch″, a Science Framework of Technische Universität Berlin and Charité - Universitätsmedizin Berlin, 10623 Berlin, Germany.

Publikováno v: JACS Au [JACS Au] 2023 Aug 17; Vol. 3 (8), pp. 2123-2130. Date of Electronic Publication: 2023 Aug 17 (Print Publication: 2023).

In Cellulo Bioorthogonal Catalysis by Encapsulated AuPd Nanoalloys: Overcoming Intracellular Deactivation.

Autor: Rubio-Ruiz B; Edinburgh Cancer Research, Institute of Genetics and Cancer, University of Edinburgh, Crewe Road South, Edinburgh EH4 2XR, U.K.; Department of Medicinal and Organic Chemistry and Unit of Excellence in Chemistry Applied to Biomedicine and Environment, Faculty of Pharmacy, Campus Cartuja s/n, University of Granada, 18071 Granada, Spain.; GENYO, Pfizer/University of Granada/Andalusian Regional Government, PTS Granada, Avda. Ilustración 114, 18016 Granada, Spain., Pérez-López AM; Edinburgh Cancer Research, Institute of Genetics and Cancer, University of Edinburgh, Crewe Road South, Edinburgh EH4 2XR, U.K.; TU Berlin, Institut für Biotechnologie, Aufgang 17-1, Level 4, Raum 472, Gustav-Meyer-Allee 25, 13355 Berlin, Germany., Uson L; Instituto de Nanociencia y Materiales de Aragón (INMA), CSIC-Universidad de Zaragoza, 50009 Zaragoza, Spain.; Department of Chemical Engineering and Environmental Technologies, University of Zaragoza, 50018 Zaragoza, Spain., Ortega-Liebana MC; Edinburgh Cancer Research, Institute of Genetics and Cancer, University of Edinburgh, Crewe Road South, Edinburgh EH4 2XR, U.K.; Department of Medicinal and Organic Chemistry and Unit of Excellence in Chemistry Applied to Biomedicine and Environment, Faculty of Pharmacy, Campus Cartuja s/n, University of Granada, 18071 Granada, Spain.; GENYO, Pfizer/University of Granada/Andalusian Regional Government, PTS Granada, Avda. Ilustración 114, 18016 Granada, Spain., Valero T; Edinburgh Cancer Research, Institute of Genetics and Cancer, University of Edinburgh, Crewe Road South, Edinburgh EH4 2XR, U.K.; Department of Medicinal and Organic Chemistry and Unit of Excellence in Chemistry Applied to Biomedicine and Environment, Faculty of Pharmacy, Campus Cartuja s/n, University of Granada, 18071 Granada, Spain.; GENYO, Pfizer/University of Granada/Andalusian Regional Government, PTS Granada, Avda. Ilustración 114, 18016 Granada, Spain., Arruebo M; Instituto de Nanociencia y Materiales de Aragón (INMA), CSIC-Universidad de Zaragoza, 50009 Zaragoza, Spain.; Department of Chemical Engineering and Environmental Technologies, University of Zaragoza, 50018 Zaragoza, Spain.; Networking Research Center on Bioengineering Biomaterials and Nanomedicine (CIBER- BBN), Instituto de Salud Carlos III, 28029 Madrid, Spain., Hueso JL; Instituto de Nanociencia y Materiales de Aragón (INMA), CSIC-Universidad de Zaragoza, 50009 Zaragoza, Spain.; Department of Chemical Engineering and Environmental Technologies, University of Zaragoza, 50018 Zaragoza, Spain.; Networking Research Center on Bioengineering Biomaterials and Nanomedicine (CIBER- BBN), Instituto de Salud Carlos III, 28029 Madrid, Spain., Sebastian V; Instituto de Nanociencia y Materiales de Aragón (INMA), CSIC-Universidad de Zaragoza, 50009 Zaragoza, Spain.; Department of Chemical Engineering and Environmental Technologies, University of Zaragoza, 50018 Zaragoza, Spain.; Networking Research Center on Bioengineering Biomaterials and Nanomedicine (CIBER- BBN), Instituto de Salud Carlos III, 28029 Madrid, Spain., Santamaria J; Instituto de Nanociencia y Materiales de Aragón (INMA), CSIC-Universidad de Zaragoza, 50009 Zaragoza, Spain.; Department of Chemical Engineering and Environmental Technologies, University of Zaragoza, 50018 Zaragoza, Spain.; Networking Research Center on Bioengineering Biomaterials and Nanomedicine (CIBER- BBN), Instituto de Salud Carlos III, 28029 Madrid, Spain., Unciti-Broceta A; Edinburgh Cancer Research, Institute of Genetics and Cancer, University of Edinburgh, Crewe Road South, Edinburgh EH4 2XR, U.K.

Publikováno v: Nano letters [Nano Lett] 2023 Feb 08; Vol. 23 (3), pp. 804-811. Date of Electronic Publication: 2023 Jan 17.

A minimally-masked inactive prodrug of panobinostat that is bioorthogonally activated by gold chemistry.

Autor: Rubio-Ruiz B; Cancer Research UK Edinburgh Centre, Institute of Genetics & Cancer, University of Edinburgh, Edinburgh, UK. Electronic address: belenrubio@ugr.es., Pérez-López AM; Cancer Research UK Edinburgh Centre, Institute of Genetics & Cancer, University of Edinburgh, Edinburgh, UK., Sebastián V; Department of Chemical Engineering, University of Zaragoza, Campus Río Ebro-Edificio I+D, C/ Poeta Mariano Esquillor S/N, 50018 Zaragoza, Spain; Instituto de Nanociencia y Materiales de Aragón (INMA), CSIC-Universidad de Zaragoza, Zaragoza 50009, Spain; Networking Research Center on Bioengineering Biomaterials and Nanomedicine (CIBER- BBN), Madrid, Spain., Unciti-Broceta A; Cancer Research UK Edinburgh Centre, Institute of Genetics & Cancer, University of Edinburgh, Edinburgh, UK. Electronic address: asier.ub@ed.ac.uk.

Publikováno v: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2021 Jul 01; Vol. 41, pp. 116217. Date of Electronic Publication: 2021 May 15.

Bioorthogonal Uncaging of Cytotoxic Paclitaxel through Pd Nanosheet-Hydrogel Frameworks.

Autor: Pérez-López AM; Cancer Cancer Research UK Edinburgh Centre, Institute of Genetics and Molecular Medicine, University of Edinburgh, Crewe Road South, Edinburgh EH4 2XR, U.K., Rubio-Ruiz B; Cancer Cancer Research UK Edinburgh Centre, Institute of Genetics and Molecular Medicine, University of Edinburgh, Crewe Road South, Edinburgh EH4 2XR, U.K., Valero T; Cancer Cancer Research UK Edinburgh Centre, Institute of Genetics and Molecular Medicine, University of Edinburgh, Crewe Road South, Edinburgh EH4 2XR, U.K., Contreras-Montoya R; Departamento de Quı́mica Orgánica, Facultad de Ciencias, Universidad de Granada, Campus de Fuentenueva s/n, Granada 18002, Spain., Álvarez de Cienfuegos L; Departamento de Quı́mica Orgánica, Facultad de Ciencias, Universidad de Granada, Campus de Fuentenueva s/n, Granada 18002, Spain., Sebastián V; Department of Chemical Engineering and Environmental Technology; Instituto de Nanociencia y Materiales de Aragón (INMA), CSIC-Universidad de Zaragoza, Zaragoza 50009, Spain.; Networking Research Center on Bioengineering Biomaterials and Nanomedicine (CIBER- BBN), Madrid 28029, Spain., Santamaría J; Department of Chemical Engineering and Environmental Technology; Instituto de Nanociencia y Materiales de Aragón (INMA), CSIC-Universidad de Zaragoza, Zaragoza 50009, Spain.; Networking Research Center on Bioengineering Biomaterials and Nanomedicine (CIBER- BBN), Madrid 28029, Spain., Unciti-Broceta A; Cancer Cancer Research UK Edinburgh Centre, Institute of Genetics and Molecular Medicine, University of Edinburgh, Crewe Road South, Edinburgh EH4 2XR, U.K.

Publikováno v: Journal of medicinal chemistry [J Med Chem] 2020 Sep 10; Vol. 63 (17), pp. 9650-9659. Date of Electronic Publication: 2020 Aug 17.

Bioorthogonal Uncaging of the Active Metabolite of Irinotecan by Palladium-Functionalized Microdevices.

Autor: Adam C; Cancer Research UK Edinburgh Centre, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, UK., Pérez-López AM; Cancer Research UK Edinburgh Centre, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, UK., Hamilton L; Centre for Neurogeneration, The Chancellor's Building, University of Edinburgh, UK., Rubio-Ruiz B; Cancer Research UK Edinburgh Centre, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, UK., Bray TL; Cancer Research UK Edinburgh Centre, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, UK., Sieger D; Cancer Research UK Edinburgh Centre, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, UK.; Centre for Neurogeneration, The Chancellor's Building, University of Edinburgh, UK., Brennan PM; Cancer Research UK Edinburgh Centre, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, UK.; Centre for Clinical Brain Sciences, University of Edinburgh, UK., Unciti-Broceta A; Cancer Research UK Edinburgh Centre, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, UK.

Publikováno v: Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2018 Nov 13; Vol. 24 (63), pp. 16783-16790. Date of Electronic Publication: 2018 Nov 08.