Mathematical model of CAR-T-cell therapy for a B-cell Lymphoma lymph node

Autor: Sabir, Soukaina, León-Triana, Odelaisy, Serrano, Sergio, Barrio, Roberto, Pérez-García, Victor M.

CAR-T cell therapies have demonstrated significant success in treating B-cell leukemia in children and young adults. However, their effectiveness in treating B-cell lymphomas has been limited. Unlike leukemia, lymphoma often manifests as solid masses

Externí odkaz: http://arxiv.org/abs/2409.01164

A mathematical model for fibrous dysplasia: The role of the flow of mutant cells

Autor: Soloviova, Mariia, Vargas, Juan Carlos Beltran, de Castro, Luis Fernandez, Belmonte-Beitia, Juan, Pérez-García, Víctor M., Caballero, Magdalena

Fibrous dysplasia (FD) is a mosaic non-inheritable genetic disorder of the skeleton in which normal bone is replaced by structurally unsound fibro-osseous tissue. There is no curative treatment for FD, partly because its pathophysiology is not yet fu

Externí odkaz: http://arxiv.org/abs/2402.07724

The Brain Tumor Segmentation (BraTS-METS) Challenge 2023: Brain Metastasis Segmentation on Pre-treatment MRI

Autor: Moawad, Ahmed W., Janas, Anastasia, Baid, Ujjwal, Ramakrishnan, Divya, Saluja, Rachit, Ashraf, Nader, Maleki, Nazanin, Jekel, Leon, Yordanov, Nikolay, Fehringer, Pascal, Gkampenis, Athanasios, Amiruddin, Raisa, Manteghinejad, Amirreza, Adewole, Maruf, Albrecht, Jake, Anazodo, Udunna, Aneja, Sanjay, Anwar, Syed Muhammad, Bergquist, Timothy, Chiang, Veronica, Chung, Verena, Conte, Gian Marco, Dako, Farouk, Eddy, James, Ezhov, Ivan, Khalili, Nastaran, Farahani, Keyvan, Iglesias, Juan Eugenio, Jiang, Zhifan, Johanson, Elaine, Kazerooni, Anahita Fathi, Kofler, Florian, Krantchev, Kiril, LaBella, Dominic, Van Leemput, Koen, Li, Hongwei Bran, Linguraru, Marius George, Liu, Xinyang, Meier, Zeke, Menze, Bjoern H, Moy, Harrison, Osenberg, Klara, Piraud, Marie, Reitman, Zachary, Shinohara, Russell Takeshi, Wang, Chunhao, Wiestler, Benedikt, Wiggins, Walter, Shafique, Umber, Willms, Klara, Avesta, Arman, Bousabarah, Khaled, Chakrabarty, Satrajit, Gennaro, Nicolo, Holler, Wolfgang, Kaur, Manpreet, LaMontagne, Pamela, Lin, MingDe, Lost, Jan, Marcus, Daniel S., Maresca, Ryan, Merkaj, Sarah, Pedersen, Gabriel Cassinelli, von Reppert, Marc, Sotiras, Aristeidis, Teytelboym, Oleg, Tillmans, Niklas, Westerhoff, Malte, Youssef, Ayda, Godfrey, Devon, Floyd, Scott, Rauschecker, Andreas, Villanueva-Meyer, Javier, Pfluger, Irada, Cho, Jaeyoung, Bendszus, Martin, Brugnara, Gianluca, Cramer, Justin, Perez-Carillo, Gloria J. Guzman, Johnson, Derek R., Kam, Anthony, Kwan, Benjamin Yin Ming, Lai, Lillian, Lall, Neil U., Memon, Fatima, Krycia, Mark, Patro, Satya Narayana, Petrovic, Bojan, So, Tiffany Y., Thompson, Gerard, Wu, Lei, Schrickel, E. Brooke, Bansal, Anu, Barkhof, Frederik, Besada, Cristina, Chu, Sammy, Druzgal, Jason, Dusoi, Alexandru, Farage, Luciano, Feltrin, Fabricio, Fong, Amy, Fung, Steve H., Gray, R. Ian, Ikuta, Ichiro, Iv, Michael, Postma, Alida A., Mahajan, Amit, Joyner, David, Krumpelman, Chase, Letourneau-Guillon, Laurent, Lincoln, Christie M., Maros, Mate E., Miller, Elka, Moron, Fanny, Nimchinsky, Esther A., Ozsarlak, Ozkan, Patel, Uresh, Rohatgi, Saurabh, Saha, Atin, Sayah, Anousheh, Schwartz, Eric D., Shih, Robert, Shiroishi, Mark S., Small, Juan E., Tanwar, Manoj, Valerie, Jewels, Weinberg, Brent D., White, Matthew L., Young, Robert, Zohrabian, Vahe M., Azizova, Aynur, Bruseler, Melanie Maria Theresa, Ghonim, Mohanad, Ghonim, Mohamed, Okar, Abdullah, Pasquini, Luca, Sharifi, Yasaman, Singh, Gagandeep, Sollmann, Nico, Soumala, Theodora, Taherzadeh, Mahsa, Vollmuth, Philipp, Foltyn-Dumitru, Martha, Malhotra, Ajay, Abayazeed, Aly H., Dellepiane, Francesco, Lohmann, Philipp, Perez-Garcia, Victor M., Elhalawani, Hesham, de Verdier, Maria Correia, Al-Rubaiey, Sanaria, Armindo, Rui Duarte, Ashraf, Kholod, Asla, Moamen M., Badawy, Mohamed, Bisschop, Jeroen, Lomer, Nima Broomand, Bukatz, Jan, Chen, Jim, Cimflova, Petra, Corr, Felix, Crawley, Alexis, Deptula, Lisa, Elakhdar, Tasneem, Shawali, Islam H., Faghani, Shahriar, Frick, Alexandra, Gulati, Vaibhav, Haider, Muhammad Ammar, Hierro, Fatima, Dahl, Rasmus Holmboe, Jacobs, Sarah Maria, Hsieh, Kuang-chun Jim, Kandemirli, Sedat G., Kersting, Katharina, Kida, Laura, Kollia, Sofia, Koukoulithras, Ioannis, Li, Xiao, Abouelatta, Ahmed, Mansour, Aya, Maria-Zamfirescu, Ruxandra-Catrinel, Marsiglia, Marcela, Mateo-Camacho, Yohana Sarahi, McArthur, Mark, McDonnell, Olivia, McHugh, Maire, Moassefi, Mana, Morsi, Samah Mostafa, Munteanu, Alexander, Nandolia, Khanak K., Naqvi, Syed Raza, Nikanpour, Yalda, Alnoury, Mostafa, Nouh, Abdullah Mohamed Aly, Pappafava, Francesca, Patel, Markand D., Petrucci, Samantha, Rawie, Eric, Raymond, Scott, Roohani, Borna, Sabouhi, Sadeq, Sanchez-Garcia, Laura M., Shaked, Zoe, Suthar, Pokhraj P., Altes, Talissa, Isufi, Edvin, Dhemesh, Yaseen, Gass, Jaime, Thacker, Jonathan, Tarabishy, Abdul Rahman, Turner, Benjamin, Vacca, Sebastiano, Vilanilam, George K., Warren, Daniel, Weiss, David, Worede, Fikadu, Yousry, Sara, Lerebo, Wondwossen, Aristizabal, Alejandro, Karargyris, Alexandros, Kassem, Hasan, Pati, Sarthak, Sheller, Micah, Link, Katherine E., Calabrese, Evan, Tahon, Nourel hoda, Nada, Ayman, Velichko, Yuri S., Bakas, Spyridon, Rudie, Jeffrey D., Aboian, Mariam

The translation of AI-generated brain metastases (BM) segmentation into clinical practice relies heavily on diverse, high-quality annotated medical imaging datasets. The BraTS-METS 2023 challenge has gained momentum for testing and benchmarking algor

Externí odkaz: http://arxiv.org/abs/2306.00838

Universal scaling laws rule explosive growth inhuman cancers

Autor: Pérez-García, Víctor M., Calvo, Gabriel F., Bosque, Jesús J., León-Triana, Odelaisy, Jiménez, Juan, Pérez-Beteta, Julián, Belmonte-Beitia, Juan, Valiente, Manuel, Zhu, Lucía, García-Gómez, Pedro, Sánchez-Gómez, Pilar, Miguel, Esther Hernández-San, Hortigüela, Rafael, Azimzade, Youness, Molina-García, David, Martínez, Álvaro, Rojas, Ángel Acosta, de Mendivil, Ana Ortiz, Vallette, Francois, Schucht, Philippe, Murek, Michael, Pérez-Cano, María, Albillo, David, Martínez, Antonio F. Honguero, Londoño, Germán A. Jiménez, Arana, Estanislao, Vicente, Ana M. García

Publikováno v: Nat.Phys. 16 (2020) 1232-1237

Most physical and other natural systems are complex entities composed of a large number of interacting individual elements. It is a surprising fact that they often obey the so-called scaling laws relating an observable quantity with a measure of the

Externí odkaz: http://arxiv.org/abs/2104.12708

Dynamical properties of feedback signalling in B lymphopoiesis: A mathematical modelling approach

Autor: Chulián, Salvador, Martínez-Rubio, Alvaro, Marciniak-Czochra, Anna, Stiehl, Thomas, Goñi, Cristina Blázquez, Gutiérrez, Juan Francisco Rodríguez, Orellana, Manuel Ramirez, Robleda, Ana Castillo, Pérez-García, Víctor M., Rosa, María

Haematopoiesis is the process of generation of blood cells. Lymphopoiesis generates lymphocytes, the cells in charge of the adaptive immune response. Disruptions of this process are associated with diseases like leukaemia, which is especially inciden

Externí odkaz: http://arxiv.org/abs/2007.13526