Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Pégah Jalili"'
Autor:
Pégah Jalili, Benjamin-Christoph Krause, Rachelle Lanceleur, Agnès Burel, Harald Jungnickel, Alfonso Lampen, Peter Laux, Andreas Luch, Valérie Fessard, Kevin Hogeveen
Publikováno v:
Particle and Fibre Toxicology, Vol 19, Iss 1, Pp 1-20 (2022)
Abstract Background TiO2 nanomaterials (NMs) are present in a variety of food and personal hygiene products, and consumers are exposed daily to these NMs through oral exposition. While the bulk of ingested TiO2 NMs are eliminated rapidly in stool, a
Externí odkaz:
https://doaj.org/article/fdc0619b8ed04116bbc117947356bbd6
Autor:
Sunwoo Oh, Elodie Bournique, Danae Bowen, Pégah Jalili, Ambrocio Sanchez, Ian Ward, Alexandra Dananberg, Lavanya Manjunath, Genevieve P. Tran, Bert L. Semler, John Maciejowski, Marcus Seldin, Rémi Buisson
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
The cytidine deaminase APOBEC3A is a main source of mutagenesis in many types of cancer. Here the authors reveal that transient up-regulation of APOBEC3A and other pro-inflammatory genes can occur due to viral infection and genotoxic stress via multi
Externí odkaz:
https://doaj.org/article/f03f488fd0c5499ab43ab73627e76395
Autor:
Pégah Jalili, Danae Bowen, Adam Langenbucher, Shinho Park, Kevin Aguirre, Ryan B. Corcoran, Angela G. Fleischman, Michael S. Lawrence, Lee Zou, Rémi Buisson
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
The DNA cytosine deaminases APOBEC3A and APOBEC3B have emerged from cancer genomics studies as drivers of mutation in cancers and tumor heterogeneity. Here the authors present a computational approach to identify the RNA mutations specifically driven
Externí odkaz:
https://doaj.org/article/ce56509c93e8439dabb97f9c99412c8c
Autor:
Pégah Jalili, Sylvie Huet, Rachelle Lanceleur, Gérard Jarry, Ludovic Le Hegarat, Fabrice Nesslany, Kevin Hogeveen, Valérie Fessard
Publikováno v:
Nanomaterials, Vol 10, Iss 2, p 305 (2020)
Due to several gaps remaining in the toxicological evaluation of nanomaterials (NMs), consumers and public health agencies have shown increasing concern for human health protection. In addition to aluminum (Al) microparticles, Al-containing nanomater
Externí odkaz:
https://doaj.org/article/d7766fa1f7454035a2d8514459513059
Autor:
Michael S. Lawrence, Angela G. Fleischman, Kevin Aguirre, Shinho Park, Adam Langenbucher, Ryan B. Corcoran, Lee Zou, Danae Bowen, Pégah Jalili, Rémi Buisson
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Nature Communications
Nature communications, vol 11, iss 1
Nature Communications
Nature communications, vol 11, iss 1
APOBEC3A is a cytidine deaminase driving mutagenesis, DNA replication stress and DNA damage in cancer cells. While the APOBEC3A-induced vulnerability of cancers offers an opportunity for therapy, APOBEC3A protein and mRNA are difficult to quantify in
Autor:
Fabienne Gauffre, Benjamin-Christoph Krause, Kevin Hogeveen, Caroline Fontana, Andreas Luch, Soizic Chevance, Sylvie Huet, Pégah Jalili, Yves Guichard, Agnès Burel, Valérie Fessard, Alfonso Lampen, Peter Laux
Publikováno v:
Toxicology in Vitro
Toxicology in Vitro, Elsevier, 2021, pp.105257. ⟨10.1016/j.tiv.2021.105257⟩
Toxicology in Vitro, 2022, 78, pp.105257. ⟨10.1016/j.tiv.2021.105257⟩
Toxicology in Vitro, Elsevier, 2021, pp.105257. ⟨10.1016/j.tiv.2021.105257⟩
Toxicology in Vitro, 2022, 78, pp.105257. ⟨10.1016/j.tiv.2021.105257⟩
Background: Exposure of consumers to aluminum-containing nanomaterials (Al NMs) through numerous products is an area of concern for public health agencies since human health risks are not completely elucidated. In addition, the available data on the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0779080d9b4b54625c6286ea013c059
https://hal.archives-ouvertes.fr/hal-03414646
https://hal.archives-ouvertes.fr/hal-03414646
Autor:
Pégah, Jalili, Benjamin-Christoph, Krause, Rachelle, Lanceleur, Agnès, Burel, Harald, Jungnickel, Alfonso, Lampen, Peter, Laux, Andreas, Luch, Valérie, Fessard, Kevin, Hogeveen
Publikováno v:
Particle and fibre toxicology. 19(1)
TiODespite the uptake of NM-103 and NM-104 in cells, no significant cytotoxic effects were observed in either Caco-2 or HepaRG cells treated for up to 2 weeks at NM concentrations up to 80 µg/cmThese findings indicate that although no clear effects
Autor:
Holger Sieg, Anna Lena Ellermann, Agnès Burel, Albert Braeuning, Soizic Chevance, Birgitta Maria Kunz, Alfonso Lampen, Kevin Hogeveen, Linda Böhmert, Valérie Fessard, Fabienne Gauffre, Pégah Jalili
Publikováno v:
Nanotoxicology
Nanotoxicology, 2019, 13 (7), pp.909-922. ⟨10.1080/17435390.2019.1593542⟩
Nanotoxicology, Taylor & Francis, 2019, 13 (7), pp.909-922. ⟨10.1080/17435390.2019.1593542⟩
Nanotoxicology, 2019, 13 (7), pp.909-922. ⟨10.1080/17435390.2019.1593542⟩
Nanotoxicology, Taylor & Francis, 2019, 13 (7), pp.909-922. ⟨10.1080/17435390.2019.1593542⟩
International audience; Aluminum (Al) can be ingested from food and released from packaging and can reach key organs involved in human metabolism, including the liver via systemic distribution. Recent studies discuss the occurrence of chemically dist
Autor:
Mandeep Banwait, Pégah Jalili, Jiachen Lin, Heidie Frisco-Cabanos, S. Oh, Nicole Phan, Lee Zou, Zofia Piotrowska, Marcello Stanzione, Daria Timonina, L.V. Sequist, Jeffrey A. Engelman, Varuna Nangia, Rémi Buisson, Faria M. Siddiqui, Rosemary Cobb, Aaron N. Hata, K. Dionne, Jaewon J. Lee, Hannah L. Archibald, Cyril H. Benes, Amanda K. Riley, Nicholas J. Dyson, Michael W. Lawlor, Cheong Xin Chan, Christopher J. Ott, H. Isozaki, A. Abbasi, Maria Gomez-Caraballo, Gad Getz, Adam Langenbucher, Samantha J. Bilton, Alice T. Shaw, Yosef E. Maruvka, Wenjia Su, Michael S. Lawrence, N. Nikpour
Acquired drug resistance to even the most effective anti-cancer targeted therapies remains an unsolved clinical problem. Although many drivers of acquired drug resistance have been identified1‒6, the underlying molecular mechanisms shaping tumor ev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::152a1f612e569ef1a840877cfed64792
https://doi.org/10.1101/2021.01.20.426852
https://doi.org/10.1101/2021.01.20.426852
Autor:
Kevin Hogeveen, Valérie Fessard, Fabrice Nesslany, Pégah Jalili, Ludovic Le Hégarat, Gérard Jarry, Sylvie Huet, Rachelle Lanceleur
Publikováno v:
Nanomaterials
Volume 10
Issue 2
Nanomaterials, MDPI, 2020, 10 (2), pp.305. ⟨10.3390/nano10020305⟩
Nanomaterials, Vol 10, Iss 2, p 305 (2020)
Volume 10
Issue 2
Nanomaterials, MDPI, 2020, 10 (2), pp.305. ⟨10.3390/nano10020305⟩
Nanomaterials, Vol 10, Iss 2, p 305 (2020)
Due to several gaps remaining in the toxicological evaluation of nanomaterials (NMs), consumers and public health agencies have shown increasing concern for human health protection. In addition to aluminum (Al) microparticles, Al-containing nanomater