Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Pål Jarle Johnsen"'
Autor:
Christopher Fröhlich, Vidar Sørum, Ane Molden Thomassen, Pål Jarle Johnsen, Hanna-Kirsti S. Leiros, Ørjan Samuelsen
Publikováno v:
mSphere, Vol 4, Iss 2 (2019)
ABSTRACT Infections due to carbapenemase-producing Gram-negative pathogens are associated with limited treatment options and consequently lead to increased mortality and morbidity. In response, combinations of existing β-lactams and novel β-lactama
Externí odkaz:
https://doaj.org/article/17e5f96f1a714a89b3f195058f277abd
Autor:
Iren Høyland Löhr, Nils Hülter, Eva Bernhoff, Pål Jarle Johnsen, Arnfinn Sundsfjord, Umaer Naseer
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0116516 (2015)
ObjectivesTo characterize the CTX-M-15-encoding plasmid in a Klebsiella pneumoniae ST17 strain, responsible for an outbreak at a Norwegian neonatal intensive care unit and subsequent colonization of affected children for up to two years. To identify
Externí odkaz:
https://doaj.org/article/3af5a6bd220a45b1865ff939947937dd
Natural transformation is a process where bacteria actively take up DNA from the environment and recombine it into their genome or reconvert it into extra-chromosomal genetic elements. The evolutionary benefits of transformation are still under debat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::097e396b16ab69f5e59ce0e9a118ee80
https://doi.org/10.1101/2023.03.20.532548
https://doi.org/10.1101/2023.03.20.532548
Autor:
Sergio Arredondo-Alonso, Rebecca A. Gladstone, Anna K. Pöntinen, João A. Gama, Anita C. Schürch, Val F. Lanza, Pål Jarle Johnsen, Ørjan Samuelsen, Gerry Tonkin-Hill, Jukka Corander
Extrachromosomal elements of bacterial cells such as plasmids are notorious for their importance in evolution and adaptation to changing ecology. However, high-resolution population-wide analysis of plasmids has only become accessible recently with t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b454aa4b211e7cfd979098355e35fc6
https://doi.org/10.1101/2022.12.16.520696
https://doi.org/10.1101/2022.12.16.520696
Publikováno v:
The Journal of antimicrobial chemotherapy. 77(9)
Background Cefiderocol is a novel siderophore β-lactam with improved hydrolytic stability toward β-lactamases, including carbapenemases, achieved by combining structural moieties of two clinically efficient cephalosporins, ceftazidime and cefepime.
Autor:
S. Arredondo-Alonso, Cléon F, Anita C. Schürch, Rebecca A. Gladstone, Ørjan Samuelsen, Pål Jarle Johnsen, Jukka Corander, Anna K. Pöntinen
BackgroundBacterial whole-genome sequencing based on short-read sequencing data often results in a draft assembly formed by contiguous sequences. The introduction of long-read sequencing technologies permits to unambiguously bridge those contiguous s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d74c140e3fe102f30c9ac88bd6327dc
https://doi.org/10.1101/2021.06.14.448320
https://doi.org/10.1101/2021.06.14.448320
Publikováno v:
Current opinion in microbiology. 64
Natural transformation is a process where bacterial cells actively take up free DNA from the environment and recombine it into their genome or reconvert it into extra-chromosomal genetic elements. Although this mechanism is known to mediate the uptak
Autor:
Ørjan Samuelsen, Pål Jarle Johnsen, Hanna-Kirsti S. Leiros, Christopher Fröhlich, Viivi H. A. Hirvonen, Bjarte Aarmo Lund, Marc W. van der Kamp, Klaus Harms, João Alves Gama
Publikováno v:
mSphere
mSphere, Vol 6, Iss 2 (2021)
Fröhlich, C, Hirvonen, V H A & Van Der Kamp, M W 2021, ' Cryptic β-lactamase evolution is driven by low β-lactam concentrations ', mSphere, vol. 6, no. 2, e00108-21 . https://doi.org/10.1128/mSphere.00108-21
mSphere, Vol 6, Iss 2 (2021)
Fröhlich, C, Hirvonen, V H A & Van Der Kamp, M W 2021, ' Cryptic β-lactamase evolution is driven by low β-lactam concentrations ', mSphere, vol. 6, no. 2, e00108-21 . https://doi.org/10.1128/mSphere.00108-21
Very low antibiotic concentrations have been shown to drive the evolution of antimicrobial resistance. While substantial progress has been made to understand the driving role of low concentrations during resistance development for different antimicro
Autor:
Elizabeth G. Aarag Fredheim, Catharina I M Koumans, Jónína S Guðmundsdóttir, Dan I. Andersson, Po-Cheng Tang, Pål Jarle Johnsen, Ørjan Samuelsen, Joachim Hegstad
Publikováno v:
EBioMedicine
EBioMedicine, Vol 74, Iss, Pp 103742-(2021)
EBioMedicine, Vol 74, Iss, Pp 103742-(2021)
Background Understanding drivers of antibiotic resistance evolution is fundamental for designing optimal treatment strategies and interventions to reduce the spread of antibiotic resistance. Various cytotoxic drugs used in cancer chemotherapy have an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23556a6bf5d7c0caf1a583af8f311f8c
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-472397
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-472397
Autor:
Anna K. Pöntinen, Einar Nilsen, Pål Jarle Johnsen, Bjørg Haldorsen, Karianne Wiger Gammelsrud, Paul Christoffer Lindemann, Kusti Onni Skytén, Hege E. Larsen, Åshild Marvik, Francois Pierre Alexandre Cléon, Kristina K. Bye, Jukka Corander, Ståle Tofteland, Gunnar Skov Simonsen, Martin Steinbakk, Angela Kümmel, Marit Vattøy, John A. Lees, Rebecca A. Gladstone, Marie Therese Noer, Gerry Tonkin-Hill, Iren Høyland Löhr, Ørjan Samuelsen, Alan McNally, Julian Parkhill, Stephen D. Bentley, Martin Owczarek Korsner Christensen, Reidar Hjetland, Nicholas J. Croucher
Publikováno v:
The Lancet Microbe, Vol 2, Iss 7, Pp e331-e341 (2021)
The Lancet Microbe
E341
E331
The Lancet Microbe
E341
E331
Summary: Background: The clonal diversity underpinning trends in multidrug resistant Escherichia coli causing bloodstream infections remains uncertain. We aimed to determine the contribution of individual clones to resistance over time, using large-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd079422ebecbe5bbaa280bf492581ed
http://hdl.handle.net/10852/89593
http://hdl.handle.net/10852/89593