Zobrazeno 1 - 10
of 311
pro vyhledávání: '"Pär I. Johansson"'
Autor:
Pär I. Johansson, Martin Vigstedt, Nicola S. Curry, Ross Davenport, Nicole P. Juffermans, Simon J. Stanworth, Marc Maegele, Christine Gaarder, Karim Brohi, Jakob Stensballe, Hanne H. Henriksen, for the Targeted Action for Curing Trauma-Induced Coagulopathy (TACTIC) Collaborators
Publikováno v:
Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, Vol 32, Iss 1, Pp 1-11 (2024)
Abstract Background Trauma induced coagulopathy remains to be an important cause of high transfusion requirements and mortality and shock induced endotheliopathy (SHINE) has been implicated. Methods European multicenter observational study of adult t
Externí odkaz:
https://doaj.org/article/6f8526acc1e54a36ae8c1241ebaab0d0
Autor:
Hans Johan Niklas Lorentsson, Christina R. Clausen, Daniel Faurholt-Jepsen, Katrine Bagge Hansen, Sidse Graff Jensen, Rikke Krogh-Madsen, Per G. Hagelqvist, Pär I. Johansson, Tina Vilsbøll, Filip K. Knop, Pernille Ravn
Publikováno v:
Thrombosis Journal, Vol 22, Iss 1, Pp 1-8 (2024)
Abstract Background and objective Tuberculosis disease (TB) and tuberculosis infection (TBI) have been associated with increased risk of cardiovascular disease which may be connected to infection-related haemostatic changes. It is unknown if treatmen
Externí odkaz:
https://doaj.org/article/81e89b0638874eab902ce1b0284c7cb8
Autor:
Bertram Kjerulff, Joseph Dowsett, Rikke Louise Jacobsen, Josephine Gladov, Margit Hørup Larsen, Agnete Troen Lundgaard, Karina Banasik, David Westergaard, Susan Mikkelsen, Khoa Manh Dinh, Lotte Hindhede, Kathrine Agergård Kaspersen, Michael Schwinn, Anders Juul, Betina Poulsen, Birgitte Lindegaard, Carsten Bøcker Pedersen, Clive Eric Sabel, Henning Bundgaard, Henriette Svarre Nielsen, Janne Amstrup Møller, Jens Kjærgaard Boldsen, Kristoffer Sølvsten Burgdorf, Lars Vedel Kessing, Linda Jenny Handgaard, Lise Wegner Thørner, Maria Didriksen, Mette Nyegaard, Niels Grarup, Niels Ødum, Pär I. Johansson, Poul Jennum, Ruth Frikke-Schmidt, Sanne Schou Berger, Søren Brunak, Søren Jacobsen, Thomas Folkmann Hansen, Tine Kirkeskov Lundquist, Torben Hansen, Torben Lykke Sørensen, Torben Sigsgaard, Kaspar René Nielsen, Mie Topholm Bruun, Henrik Hjalgrim, Henrik Ullum, Klaus Rostgaard, Erik Sørensen, Ole Birger Pedersen, Sisse Rye Ostrowski, Christian Erikstrup
Publikováno v:
Communications Medicine, Vol 4, Iss 1, Pp 1-15 (2024)
Abstract Background The emerging use of biomarkers in research and tailored care introduces a need for information about the association between biomarkers and basic demographics and lifestyle factors revealing expectable concentrations in healthy in
Externí odkaz:
https://doaj.org/article/2cf9df2a8b374f6abb5d546a3f0b5949
Autor:
Pär I. Johansson, Hanne H. Henriksen, Sigurður T. Karvelsson, Óttar Rolfsson, Martin Schønemann-Lund, Morten H. Bestle, Sarah McGarrity
Publikováno v:
European Journal of Medical Research, Vol 29, Iss 1, Pp 1-14 (2024)
Abstract Sepsis is a major cause of death worldwide, with a mortality rate that has remained stubbornly high. The current gold standard of risk stratifying sepsis patients provides limited mechanistic insight for therapeutic targeting. An improved ab
Externí odkaz:
https://doaj.org/article/738699080381430d9b45ae0de27a6d7f
Autor:
Hans Johan Niklas Lorentsson, Christina R. Clausen, Daniel Faurholt-Jepsen, Katrine Bagge Hansen, Sidse Graff Jensen, Rikke Krogh-Madsen, Per G. Hagelqvist, Pär I. Johansson, Tina Vilsbøll, Filip K. Knop, Pernille Ravn
Publikováno v:
Thrombosis Journal, Vol 22, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/7ef8864b7d984e4f809f4c510ab7b0f5
Autor:
Fernando Silva-Lance, Isabel Montejano-Montelongo, Eric Bautista, Lars K. Nielsen, Pär I. Johansson, Igor Marin de Mas
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 10, p 5406 (2024)
Patient blood samples are invaluable in clinical omics databases, yet current methodologies often fail to fully uncover the molecular mechanisms driving patient pathology. While genome-scale metabolic models (GEMs) show promise in systems medicine by
Externí odkaz:
https://doaj.org/article/cd561fa63a904d96ae3b416a2ce1584d
Autor:
Junru Wu, Anthony Cyr, Danielle S. Gruen, Tyler C. Lovelace, Panayiotis V. Benos, Jishnu Das, Upendra K. Kar, Tianmeng Chen, Francis X. Guyette, Mark H. Yazer, Brian J. Daley, Richard S. Miller, Brian G. Harbrecht, Jeffrey A. Claridge, Herb A. Phelan, Brian S. Zuckerbraun, Matthew D. Neal, Pär I. Johansson, Jakob Stensballe, Rami A. Namas, Yoram Vodovotz, Jason L. Sperry, Timothy R. Billiar, PAMPer study group
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Alterations in lipid metabolism and circulating lipid species have been reported in patients with acute critical illness. Here the authors show that selective rise in systemic phosphatidylethanolamine levels is a common feature of critical illness th
Externí odkaz:
https://doaj.org/article/878ce1521f7b4769bceaa30dfe45f017
Autor:
Martin Schønemann-Lund, Theis S. Itenov, Johan E. Larsson, Birgitte Lindegaard, Pär I. Johansson, Morten H. Bestle
Publikováno v:
Critical Care, Vol 26, Iss 1, Pp 1-15 (2022)
Abstract Background Endotheliopathy is suggested as pivotal pathophysiology of sepsis and trauma-associated organ failure, but its role in acute respiratory failure is not yet determined. We investigated if endotheliopathy biomarkers at ICU admission
Externí odkaz:
https://doaj.org/article/c7e3e9fe6109417f8a13626fb93fd17c
Autor:
Hanne H. Henriksen, Igor Marín de Mas, Helena Herand, Joseph Krocker, Charles E. Wade, Pär I. Johansson
Publikováno v:
Matrix Biology Plus, Vol 15, Iss , Pp 100115- (2022)
Purpose: Endotheliopathy of trauma (EoT), as defined by circulating levels of syndecan-1 ≥ 40 ng/mL, has been reported to be associated with significantly increased transfusion requirements and a doubled 30-day mortality. Increased shedding of the
Externí odkaz:
https://doaj.org/article/bc9e607d6fdf4fef99148f2f6536f929
Autor:
Theis S. Itenov, Daniel I. Sessler, Ashish K. Khanna, Sisse R. Ostrowski, Pär I. Johansson, Christian Erikstrup, Ole B. Pedersen, Sofie L. Rygård, Lars B. Holst, Morten H. Bestle, Lars Hein, Anne Lindhardt, Hami Tousi, Mads H. Andersen, Thomas Mohr, Jens D. Lundgren, Jens-Ulrik Jensen
Publikováno v:
Annals of Intensive Care, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Background We aimed to determine if the ABO blood types carry different risks of 30-day mortality, acute kidney injury (AKI), and endothelial damage in critically ill patients with sepsis. This was a retrospective cohort study of three indep
Externí odkaz:
https://doaj.org/article/6496cd451d274d34837948a1c53d4239