Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Pär Comstedt"'
Autor:
Sunita Gulati, Andreas Holm Mattsson, Sophie Schussek, Bo Zheng, Rosane B. DeOliveira, Jutamas Shaughnessy, Lisa A. Lewis, Peter A. Rice, Pär Comstedt, Sanjay Ram
Publikováno v:
mBio, Vol 14, Iss 6 (2023)
ABSTRACTA safe and effective vaccine is urgently needed to combat the global threat of multidrug-resistant (MDR) Neisseria gonorrhoeae. We screened 26 gonococcal proteins discovered by an artificial intelligence-driven platform called Efficacy Discri
Externí odkaz:
https://doaj.org/article/04fed7bbb74b447cb687510aff5f200b
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0184357 (2017)
We have previously shown that the Outer surface protein A (OspA) based Lyme borreliosis vaccine VLA15 induces protective immunity in mice. Herein, we report the induction of protective immunity by VLA15 with mouse models using ticks infected with B.
Externí odkaz:
https://doaj.org/article/edb3aab3d8b146b397f04bb7c3ee26bb
Autor:
Wolfgang Schüler, Ignas Bunikis, Jacqueline Weber-Lehman, Pär Comstedt, Sabrina Kutschan-Bunikis, Gerold Stanek, Jutta Huber, Andreas Meinke, Sven Bergström, Urban Lundberg
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0120548 (2015)
The main Borrelia species causing Lyme borreliosis in Europe and Asia are Borrelia afzelii, B. garinii, B. burgdorferi and B. bavariensis. This is in contrast to the United States, where infections are exclusively caused by B. burgdorferi. Until to d
Externí odkaz:
https://doaj.org/article/5767610401b74e03a2f1600754196cae
Autor:
Pär Comstedt, Sven Bergström, Björn Olsen, Ulf Garpmo, Lisette Marjavaara, Hans Mejlon, Alan G. Barbour, Jonas Bunikis
Publikováno v:
Emerging Infectious Diseases, Vol 12, Iss 7, Pp 1087-1102 (2006)
To define the role of birds as reservoirs and disseminators of Borrelia spirochetes, we characterized tick infestation and reservoir competence of migratory passerine birds in Sweden. A total of 1,120 immature Ixodes ricinus ticks were removed from 1
Externí odkaz:
https://doaj.org/article/827165dc629b47c29f3d304ba5aab262
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e113294 (2014)
There is currently no Lyme borreliosis vaccine available for humans, although it has been shown that the disease can be prevented by immunization with an OspA-based vaccine (LYMErix). Outer surface protein A (OspA) is one of the dominant antigens exp
Externí odkaz:
https://doaj.org/article/e9db15a7e6e44ec894557522b7e76c84
Autor:
Pär Comstedt, Loreta Asokliene, Ingvar Eliasson, Björn Olsen, Anders Wallensten, Jonas Bunikis, Sven Bergström
Publikováno v:
PLoS ONE, Vol 4, Iss 6, p e5841 (2009)
Borrelia garinii, a causative agent of Lyme borreliosis in Europe and Asia, is naturally maintained in marine and terrestrial enzootic cycles, which primarily involve birds, including seabirds and migratory passerines. These bird groups associate wit
Externí odkaz:
https://doaj.org/article/e7e4030512ca485ea8eb3b89aed728d9
Autor:
Stefan Seidel, Wolfgang Schüler, Pär Comstedt, Ivan Gomez, Andreas Meinke, Abhijeet Nayak, Urban Lundberg
Publikováno v:
Infect Immun
Infection and immunity, 88(4):e00917-19. American Society for Microbiology
Infection and immunity, 88(4):e00917-19. American Society for Microbiology
The development of vaccines for prevention of diseases caused by pathogenic species can encounter major obstacles if high sequence diversity is observed between individual strains. Therefore, development might be restricted either to conserved antige
Autor:
Wolfgang Schüler, Pär Comstedt, Robert Schlegl, Andreas Meinke, Urban Lundberg, Markus Hanner
Publikováno v:
Vaccine. 33:5982-5988
Lyme borreliosis (LB) is the most common vector-borne disease in the northern hemisphere and there is no vaccine available for disease prevention. The majority of LB cases in Europe are caused by four different Borrelia species expressing six differe
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 9, p e0184357 (2017)
PLoS ONE, Vol 12, Iss 9, p e0184357 (2017)
We have previously shown that the Outer surface protein A (OspA) based Lyme borreliosis vaccine VLA15 induces protective immunity in mice. Herein, we report the induction of protective immunity by VLA15 with mouse models using ticks infected with B.
Autor:
Wolfgang Schüler, Urban Lundberg, Benjamin Wizel, Andreas Meinke, Markus Hanner, Pär Comstedt, Albina Poljak
Publikováno v:
Vaccine. 30:4398-4406
The three Borrelia species, Borrelia afzelii, Borrelia burgdorferi and Borrelia garinii are the main species causing the most common tick-borne zoonosis, Lyme borreliosis. By applying a genomic approach relying on human antibodies we have identified