Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Päivi, Lindholm"'
Autor:
Jenni E. Anttila, Olli S. Mattila, Hock-Kean Liew, Kert Mätlik, Eero Mervaala, Päivi Lindholm, Maria Lindahl, Perttu J. Lindsberg, Kuan-Yin Tseng, Mikko Airavaara
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-24 (2024)
Abstract Mesencephalic astrocyte-derived neurotrophic factor (MANF) has cytoprotective effects on various injuries, including cerebral ischemia, and it can promote recovery even when delivered intracranially several days after ischemic stroke. In the
Externí odkaz:
https://doaj.org/article/cd3742bb5b894f548ea64724f99c629c
Autor:
Emmi Pakarinen, Päivi Lindholm
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2023)
Parkinson’s disease (PD) is a progressive neurodegenerative disease characterized by gradual loss of midbrain dopamine neurons, leading to impaired motor function. Preclinical studies have indicated cerebral dopamine neurotrophic factor (CDNF) and
Externí odkaz:
https://doaj.org/article/ab1e912e62f74c58aa680c30a2f99210
Autor:
Vera Kovaleva, Li-Ying Yu, Larisa Ivanova, Olesya Shpironok, Jinhan Nam, Ave Eesmaa, Esa-Pekka Kumpula, Sven Sakson, Urve Toots, Mart Ustav, Juha T. Huiskonen, Merja H. Voutilainen, Päivi Lindholm, Mati Karelson, Mart Saarma
Publikováno v:
Cell Reports, Vol 42, Iss 2, Pp 112066- (2023)
Summary: Mesencephalic astrocyte-derived neurotrophic factor (MANF) is an endoplasmic reticulum (ER)-located protein with cytoprotective effects in neurons and pancreatic β cells in vitro and in models of neurodegeneration and diabetes in vivo. Howe
Externí odkaz:
https://doaj.org/article/5219a8ab6680491fa637a30370d90b44
Autor:
Neuza S. Sousa, Margarida F. Brás, Inês B. Antunes, Päivi Lindholm, Joana Neves, Pedro Sousa-Victor
Publikováno v:
Nature Aging. 3:585-599
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b811c086c6130e65cca406782c07184
https://doi.org/10.1038/s43587-023-00382-5
https://doi.org/10.1038/s43587-023-00382-5
Publikováno v:
BMC Genetics, Vol 18, Iss 1, Pp 1-19 (2017)
Abstract Background Mesencephalic Astrocyte-derived Neurotrophic Factor (MANF) and Cerebral Dopamine Neurotrophic Factor (CDNF) form an evolutionarily conserved family of neurotrophic factors. Orthologues for MANF/CDNF are the only neurotrophic facto
Externí odkaz:
https://doaj.org/article/02a492723c6d44d59d1df4b281eba4cd
Publikováno v:
Neurobiology of Disease, Vol 97, Iss , Pp 90-102 (2017)
Cerebral dopamine neurotrophic factor (CDNF) and mesencephalic astrocyte-derived neurotrophic factor (MANF) promote the survival of midbrain dopaminergic neurons which degenerate in Parkinson's disease (PD). However, CDNF and MANF are structurally an
Externí odkaz:
https://doaj.org/article/3b8ae70812f149bca90dad546b2a5e2b
Autor:
Tatiana Danilova, Emilia Galli, Emmi Pakarinen, Erik Palm, Päivi Lindholm, Mart Saarma, Maria Lindahl
Publikováno v:
Frontiers in Endocrinology, Vol 10 (2019)
Mesencephalic astrocyte-derived neurotrophic factor (MANF) and cerebral dopamine neurotrophic factor (CDNF) form a family of atypical growth factors discovered for their neuroprotective properties in the central nervous system (CNS) in animal models
Externí odkaz:
https://doaj.org/article/8030f1f6315340aba45a979396c93b13
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
BackgroundMesencephalic astrocyte-derived neurotrophic factor (MANF) and cerebral dopamine neurotrophic factor (CDNF) promote the survival of midbrain dopamine neurons in animal models of Parkinson’s disease (PD). However, little is known about end
Externí odkaz:
https://doaj.org/article/b8173a31e842408b8f0679ea40506097
Autor:
Emilia Galli, Päivi Lindholm, Leena-Stiina Kontturi, Mart Saarma, Arto Urtti, Marjo Yliperttula
Publikováno v:
Cell Transplantation, Vol 28 (2019)
Cerebral dopamine neurotrophic factor (CDNF) shows beneficial effects in rodent models of Parkinson’s and Alzheimer’s disease. The brain is a challenging target for protein therapy due to its exclusive blood–brain barrier. Hence, the therapeuti
Externí odkaz:
https://doaj.org/article/8f23ad08c57b4176a345db4d261233c1
Autor:
Francesca De Lorenzo, Patrick Lüningschrör, Jinhan Nam, Liam Beckett, Federica Pilotto, Emilia Galli, Päivi Lindholm, Cora Rüdt von Collenberg, Simon Tii Mungwa, Sibylle Jablonka, Julia Kauder, Nadine Thau-Habermann, Susanne Petri, Dan Lindholm, Smita Saxena, Michael Sendtner, Mart Saarma, Merja H Voutilainen
Publikováno v:
De Lorenzo, Francesca; Lüningschrör, Patrick; Nam, Jinhan; Beckett, Liam; Pilotto, Federica; Galli, Emilia; Lindholm, Päivi; Rüdt von Collenberg, Cora; Tii Mungwa, Simon; Jablonka, Sibylle; Kauder, Julia; Thau-Habermann, Nadine; Petri, Susanne; Lindholm, Dan; Saxena, Smita; Sendtner, Michael; Saarma, Mart; Voutilainen, Merja H (2023). CDNF rescues motor neurons in models of amyotrophic lateral sclerosis by targeting endoplasmic reticulum stress. (In Press). Brain : a journal of neurology Oxford University Press 10.1093/brain/awad087
Amyotrophic lateral sclerosis is a progressive neurodegenerative disease that affects motor neurons in the spinal cord, brainstem and motor cortex, leading to paralysis and eventually to death within 3–5 years of symptom onset. To date, no cure or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07df6b4ff858dd1d31c2e6eea8fb8b83
https://boris.unibe.ch/180302/1/awad087.pdf
https://boris.unibe.ch/180302/1/awad087.pdf
