Spermine protects from LPS-induced memory deficit via BDNF and TrkB activation

Autor: Pâmella K. Frühauf-Perez, Micheli M. Pillat, Cristiane Signor, Carlos Fernando Mello, Henning Ulrich, Arithane Lorena Wendel, Maribel Antonello Rubin, Fernanda Rossatto Temp

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Lipopolysaccharide (LPS) has been long known to promote neuroinflammation and learning and memory deficits. Since spermine, one of the main natural polyamines in the central nervous system, protects from LPS-induced memory deficit by a mechanism that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e0a1d1f458eac804b4c36e56748b62b
https://doi.org/10.1016/j.nlm.2018.02.012