HDAC1/2-Dependent P0 Expression Maintains Paranodal and Nodal Integrity Independently of Myelin Stability through Interactions with Neurofascins.

Autor: Valérie Brügger, Stefanie Engler, Jorge A Pereira, Sophie Ruff, Michael Horn, Hans Welzl, Emmanuelle Münger, Adrien Vaquié, Páris N M Sidiropoulos, Boris Egger, Peter Yotovski, Luis Filgueira, Christian Somandin, Tessa C Lühmann, Maurizio D'Antonio, Teppei Yamaguchi, Patrick Matthias, Ueli Suter, Claire Jacob

Publikováno v: PLoS Biology, Vol 13, Iss 9, p e1002258 (2015)

The pathogenesis of peripheral neuropathies in adults is linked to maintenance mechanisms that are not well understood. Here, we elucidate a novel critical maintenance mechanism for Schwann cell (SC)-axon interaction. Using mouse genetics, ablation o

Externí odkaz: https://doaj.org/article/c29881d88a474c0781bc7d0726b1f045

Author response: Schwann cells, but not Oligodendrocytes, Depend Strictly on Dynamin 2 Function

Autor: Christian Somandin, Lukas G. Nageli, Klaus V. Toyka, Valentina Tadini, Michaela Miehe, Carsten Wessig, Andrea Ommer, Daniel Gerber, Páris N. M. Sidiropoulos, Vanessa Suter, Joanne Gerber, Elisa Tinelli, Jorge A. Pereira, Monica Ghidinelli, Gianluca Figlia, Ueli Suter

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::698385ac9f80553258d5e6cfae7705c3
https://doi.org/10.7554/elife.42404.024

Dynamin 2 mutations in Charcot-Marie-Tooth neuropathy highlight the importance of clathrin-mediated endocytosis in myelination

Autor: Ueli Suter, Thomas Bock, Páris N. M. Sidiropoulos, Axel Niemann, Dies Meijer, Michaela Miehe, Rohini Kuner, Carole I. Oertli, Elisa Tinelli, Bernd Wollscheid

Publikováno v: Brain : a journal of neurology
Brain, 135, 1395-1411. Oxford University Press
Brain: A Journal of Neurology, 135 (5)

Mutations in dynamin 2 (DNM2) lead to dominant intermediate Charcot-Marie-Tooth neuropathy type B, while a different set of DNM2 mutations cause autosomal dominant centronuclear myopathy. In this study, we aimed to elucidate the disease mechanisms in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5d94a705c584819a090009ad10b8375
https://pure.eur.nl/en/publications/f53c4445-b8d4-454c-848e-0f4cc64555dd

Insulator Protein Helps Organize the Gaps in the Axon's Insulation

Autor: Valérie Brügger, Stefanie Engler, Christian Somandin, Hans Welzl, Maurizio D'Antonio, Teppei Yamaguchi, Tessa Lühmann, Emmanuelle Münger, Páris N. M. Sidiropoulos, Sophie Ruff, Jorge A. Pereira, Adrien Vaquié, Ueli Suter, Boris Egger, Michael Horn, Peter Yotovski, Claire Jacob, Luis Filgueira, Patrick Matthias

Publikováno v: PLOS Biology
PLoS biology
PLoS Biology, 13 (9)
BASE-Bielefeld Academic Search Engine
PLoS Biology, Vol 13, Iss 9, p e1002258 (2015)
PLoS Biology

The pathogenesis of peripheral neuropathies in adults is linked to maintenance mechanisms that are not well understood. Here, we elucidate a novel critical maintenance mechanism for Schwann cell (SC)–axon interaction. Using mouse genetics, ablation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed489c227a650b06f33ec280927d52cf
http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.1002258