Monitoring correlates of SARS-CoV-2 infection in cell culture using a two-photon-active calcium-sensitive dye.

Autor: Máthé D; Department of Biophysics and Radiation Biology, Semmelweis University, Tűzoltó utca 37-47, 1094, Budapest, Hungary. mathe.domokos@med.semmelweis-univ.hu.; In Vivo Imaging Advanced Core Facility, Hungarian Centre of Excellence for Molecular Medicine, Tűzoltó utca 37-47, 1094, Budapest, Hungary. mathe.domokos@med.semmelweis-univ.hu.; HUN-REN Physical Virology Research Group, Semmelweis University, Tűzoltó utca 37-47, 1094, Budapest, Hungary. mathe.domokos@med.semmelweis-univ.hu., Szalay G; Laboratory of 3D Functional Network and Dendritic Imaging, HUN-REN Institute of Experimental Medicine, Szigony utca 43, 1083, Budapest, Hungary.; BrainVisionCenter, Liliom utca 43-45, 1094, Budapest, Hungary., Cseri L; BrainVisionCenter, Liliom utca 43-45, 1094, Budapest, Hungary.; Femtonics Ltd., Tűzoltó utca 59, 1094, Budapest, Hungary., Kis Z; National Center for Public Health, Albert Flórián út 2-6, 1097, Budapest, Hungary., Pályi B; National Center for Public Health, Albert Flórián út 2-6, 1097, Budapest, Hungary., Földes G; National Heart and Lung Institute, Imperial College London, Du Cane Road, London, W12 0NN, UK.; Heart and Vascular Center, Semmelweis University, Városmajor utca. 68, 1122, Budapest, Hungary., Kovács N; In Vivo Imaging Advanced Core Facility, Hungarian Centre of Excellence for Molecular Medicine, Tűzoltó utca 37-47, 1094, Budapest, Hungary., Fülöp A; Femtonics Ltd., Tűzoltó utca 59, 1094, Budapest, Hungary., Szepesi Á; Laboratory of 3D Functional Network and Dendritic Imaging, HUN-REN Institute of Experimental Medicine, Szigony utca 43, 1083, Budapest, Hungary.; BrainVisionCenter, Liliom utca 43-45, 1094, Budapest, Hungary., Hajdrik P; Department of Biophysics and Radiation Biology, Semmelweis University, Tűzoltó utca 37-47, 1094, Budapest, Hungary., Csomos A; Femtonics Ltd., Tűzoltó utca 59, 1094, Budapest, Hungary.; Hevesy György PhD School of Chemistry, Eötvös Loránd University, Pázmány Péter sétány 1/A, 1117, Budapest, Hungary., Zsembery Á; Department of Oral Biology, Faculty of Dentistry, Semmelweis University, Nagyvárad tér 4, 1089, Budapest, Hungary., Kádár K; Department of Oral Biology, Faculty of Dentistry, Semmelweis University, Nagyvárad tér 4, 1089, Budapest, Hungary., Katona G; Two-Photon Measurement Technology Group, The Faculty of Information Technology, Pázmány Péter Catholic University, Szigony utca 50/A, 1083, Budapest, Hungary., Mucsi Z; BrainVisionCenter, Liliom utca 43-45, 1094, Budapest, Hungary. zmucsi@femtonics.eu.; Femtonics Ltd., Tűzoltó utca 59, 1094, Budapest, Hungary. zmucsi@femtonics.eu.; Institute of Chemistry, Faculty of Materials Science and Engineering, University of Miskolc, Egyetem tér 1, 3515, Miskolc, Hungary. zmucsi@femtonics.eu., Rózsa BJ; Laboratory of 3D Functional Network and Dendritic Imaging, HUN-REN Institute of Experimental Medicine, Szigony utca 43, 1083, Budapest, Hungary. rozsa.balazs@koki.hu.; BrainVisionCenter, Liliom utca 43-45, 1094, Budapest, Hungary. rozsa.balazs@koki.hu.; Two-Photon Measurement Technology Group, The Faculty of Information Technology, Pázmány Péter Catholic University, Szigony utca 50/A, 1083, Budapest, Hungary. rozsa.balazs@koki.hu., Kovács E; Two-Photon Measurement Technology Group, The Faculty of Information Technology, Pázmány Péter Catholic University, Szigony utca 50/A, 1083, Budapest, Hungary. kovacs.ervin@ttk.hu.; Institute of Materials and Environmental Chemistry, HUN-REN Research Centre for Natural Sciences, Magyar Tudósok körútja 2, 1117, Budapest, Hungary. kovacs.ervin@ttk.hu.

Publikováno v: Cellular & molecular biology letters [Cell Mol Biol Lett] 2024 Jul 19; Vol. 29 (1), pp. 105. Date of Electronic Publication: 2024 Jul 19.

A novel ACE2 decoy for both neutralization of SARS-CoV-2 variants and killing of infected cells

Autor: Kegler, A., Drewitz, L., Arndt, C., Daglar, C., Rodrigues Loureiro, L. R., Mitwasi, N., Neuber, C., González Soto, K. E., Bartsch, T., Baraban, L., Ziehr, H., Heine, M., Nieter, A., Moreira-Soto, A., Kühne, A., Drexler, J. F., Seliger, B., Laube, M., Máthé, D., Pályi, B., Hajdrik, P., Forgách, L., Kis, Z., Szigeti, K., Bergmann, R., Feldmann, A., Bachmann, M.

Publikováno v: Frontiers in Immunology 14(2023), 1204543

The COVID-19 pandemic caused by SARS-CoV-2 led to millions of infections and deaths worldwide. As this virus evolves rapidly, there is a high need for treatment options, which can win the race against new emerging variants of concern. Here, we descri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______4577::fdce3d0afa5c96d96efc48a7e94d2f77
https://www.hzdr.de/publications/Publ-37085-1

A novel ACE2 decoy for both neutralization of SARS-CoV-2 variants and killing of infected cells.

Autor: Kegler A; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany., Drewitz L; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany., Arndt C; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany.; Mildred Scheel Early Career Center, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany., Daglar C; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany., Rodrigues Loureiro L; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany., Mitwasi N; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany., Neuber C; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany., González Soto KE; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany., Bartsch T; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany., Baraban L; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany., Ziehr H; Department of Pharmaceutical Biotechnology, Fraunhofer Institute for Toxicology and Experimental Medicine (ITEM), Braunschweig, Germany., Heine M; Department of Pharmaceutical Biotechnology, Fraunhofer Institute for Toxicology and Experimental Medicine (ITEM), Braunschweig, Germany., Nieter A; Department of Pharmaceutical Biotechnology, Fraunhofer Institute for Toxicology and Experimental Medicine (ITEM), Braunschweig, Germany., Moreira-Soto A; Institute of Virology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany., Kühne A; Institute of Virology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany., Drexler JF; Institute of Virology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany., Seliger B; Medical Faculty, Martin-Luther-University Halle-Wittenberg, Halle, Germany.; Institute of Translational Immunology, Medical High School, Brandenburg an der Havel, Germany., Laube M; Department of Radiopharmaceutical and Chemical Biology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany., Máthé D; Department of Biophysics and Radiation Biology, Faculty of Medicine, Semmelweis University, Budapest, Hungary.; Hungarian Centre of Excellence for Molecular Medicine, In Vivo Imaging Advanced Core Facility, Szeged, Hungary.; CROmed Translational Research Ltd., Budapest, Hungary., Pályi B; National Biosafety Laboratory, Division of Microbiological Reference Laboratories, National Public Health Center, Budapest, Hungary., Hajdrik P; Department of Biophysics and Radiation Biology, Faculty of Medicine, Semmelweis University, Budapest, Hungary., Forgách L; Semmelweis University School of Pharmacy, Semmelweis University, Budapest, Hungary., Kis Z; National Biosafety Laboratory, Division of Microbiological Reference Laboratories, National Public Health Center, Budapest, Hungary., Szigeti K; Department of Biophysics and Radiation Biology, Faculty of Medicine, Semmelweis University, Budapest, Hungary., Bergmann R; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany.; Department of Biophysics and Radiation Biology, Faculty of Medicine, Semmelweis University, Budapest, Hungary., Feldmann A; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany.; National Center for Tumor Diseases Dresden (NCT), German Cancer Research Center (DKFZ), Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany.; German Cancer Consortium (DKTK), Partner Site Dresden and German Cancer Research Center (DKFZ), Heidelberg, Germany., Bachmann M; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany.; National Center for Tumor Diseases Dresden (NCT), German Cancer Research Center (DKFZ), Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany.; German Cancer Consortium (DKTK), Partner Site Dresden and German Cancer Research Center (DKFZ), Heidelberg, Germany.

Publikováno v: Frontiers in immunology [Front Immunol] 2023 Jun 13; Vol. 14, pp. 1204543. Date of Electronic Publication: 2023 Jun 13 (Print Publication: 2023).

Nationwide effectiveness of five SARS-CoV-2 vaccines in Hungary-the HUN-VE study.

Autor: Vokó Z; Centre for Health Technology Assessment, Semmelweis University, Budapest, Hungary; Syreon Research Institute, Budapest, Hungary., Kiss Z; Second Department of Medicine and Nephrology-Diabetes Centre, University of Pécs Medical School, Pécs, Hungary., Surján G; Ministry of Human Resources, Budapest, Hungary; Institute of Digital Health Sciences, Semmelweis University, Budapest, Hungary., Surján O; Department of Deputy Chief Medical Officer II, National Public Health Centre, Budapest, Hungary., Barcza Z; Syntesia Medical Communications Ltd., Budapest, Hungary., Pályi B; National Biosafety Laboratory, Division of Microbiological Reference Laboratories, National Public Health Centre, Budapest, Hungary., Formanek-Balku E; Department of Public Health Strategy, Health Development and Health Monitoring, National Public Health Centre, Budapest, Hungary., Molnár GA; Second Department of Medicine and Nephrology-Diabetes Centre, University of Pécs Medical School, Pécs, Hungary., Herczeg R; Szentágothai Research Centre, University of Pécs, Pécs, Hungary., Gyenesei A; Szentágothai Research Centre, University of Pécs, Pécs, Hungary., Miseta A; Department of Laboratory Medicine, University of Pécs Medical School, Pécs, Hungary., Kollár L; Ministry of Human Resources, Budapest, Hungary., Wittmann I; Second Department of Medicine and Nephrology-Diabetes Centre, University of Pécs Medical School, Pécs, Hungary. Electronic address: istvan.wittmann@aok.pte.hu., Müller C; Department of Chief Medical Officer, National Public Health Centre, Budapest, Hungary., Kásler M; Ministry of Human Resources, Budapest, Hungary.

Publikováno v: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases [Clin Microbiol Infect] 2022 Mar; Vol. 28 (3), pp. 398-404. Date of Electronic Publication: 2021 Nov 25.

The contribution of the European high containment laboratories during the 2014–2015 Ebola Virus Disease emergency

Autor: Nisii, C., Vincenti, D., Fusco, F.M., Schmidt-Chanasit, J., Carbonnelle, C., Raoul, H., Eickmann, M., Hewson, R., Brave, A., Nuncio, S., Sanchez-Seco, M.P., Palyi, B., Kis, Z., Zange, S., Nitsche, A., Kurth, A., Strasser, M., Capobianchi, M.R., Ozin, A., Guglielmetti, P., Menel-Lemos, C., Jacob, D., Grunow, R., Ippolito, G., Di Caro, A.

Publikováno v: In Clinical Microbiology and Infection February 2017 23(2):58-60