Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Pál Stráner"'
Autor:
Dóra Nagy-Fazekas, Zsolt Fazekas, Nóra Taricska, Pál Stráner, Dóra Karancsiné Menyhárd, András Perczel
Publikováno v:
Molecules, Vol 28, Iss 15, p 5655 (2023)
Myostatin, an important negative regulator of muscle mass, is a therapeutic target for muscle atrophic disorders such as muscular dystrophy. Thus, the inhibition of myostatin presents a strategy to treat these disorders. It has long been established
Externí odkaz:
https://doaj.org/article/2dd0bfd1c1184c1b8327e552cab3d597
Autor:
István Vida, Zsolt Fazekas, Gergő Gyulai, Dóra Nagy‐Fazekas, Gyula Pálfy, Pál Stráner, Éva Kiss, András Perczel
Publikováno v:
Microbial Biotechnology, Vol 14, Iss 3, Pp 1107-1119 (2021)
Summary We developed a cost sensitive isotope labelling procedure using a fed‐batch fermentation method and tested its efficiency producing the 15N‐, 13C‐ and 15N/13C‐labelled variants of an amyloidogenic miniprotein (E5: EEEAVRLYIQWLKEGGPSSG
Externí odkaz:
https://doaj.org/article/134f0cff74d24c05a20c9df76da157bf
Autor:
Dóra Nagy-Fazekas, Pál Stráner, Péter Ecsédi, Nóra Taricska, Adina Borbély, László Nyitray, András Perczel
Publikováno v:
Bioengineering, Vol 10, Iss 3, p 389 (2023)
Antibodies are key proteins of the immune system, and they are widely used for both research and theragnostic applications. Among them, camelid immunoglobulins (IgG) differ from the canonical human IgG molecules, as their light chains are completely
Externí odkaz:
https://doaj.org/article/532fcbcce04c4c5eaab7d71a9c0ff521
Autor:
Anna J. Kiss-Szemán, Pál Stráner, Imre Jákli, Naoki Hosogi, Veronika Harmat, Dóra K. Menyhárd, András Perczel
Publikováno v:
Chemical Science. 13:7132-7142
The structure of tetrameric mammalian acylaminoacyl peptidase – a key upstream regulator of the proteasome – was determined by cryo-EM (and elucidated by MD), showing a “shutters-and-channels” substrate selection apparatus created by oligomer
Autor:
Zsolt Gulyás, Blanka Moncsek, Kamirán Áron Hamow, Pál Stráner, Zoltán Tolnai, Eszter Badics, Norbert Incze, Éva Darkó, Valéria Nagy, András Perczel, László Kovács, Vilmos Soós
Publikováno v:
The Plant journal : for cell and molecular biologyREFERENCES.
Carotenoids contribute to a variety of physiological processes in plants, functioning also as biosynthesis precursors of ABA and strigolactones (SLs). SL biosynthesis starts with the enzymatic conversion of all-trans-β-carotene to 9-cis-β-carotene
Autor:
Anna J. Kiss-Szemán, Luca Takács, Zoltán Orgován, Pál Stráner, Imre Jákli, Gitta Schlosser, Simonas Masiulis, Veronika Harmat, Dóra K. Menyhárd, András Perczel
Publikováno v:
Chemical science. 13(48)
The structure of porcine AAP (pAAP) in a covalently bound complex with meropenem was determined by cryo-EM to 2.1 Å resolution, showing the mammalian serine-protease inhibited by a carbapenem antibiotic. AAP is a modulator of the ubiquitin-proteasom
Autor:
Gyula Pálfy, István Vida, Zsolt Fazekas, Éva Kiss, András Perczel, Dóra Nagy-Fazekas, Pál Stráner, Gergő Gyulai
Publikováno v:
Microbial Biotechnology
Microbial Biotechnology, Vol 14, Iss 3, Pp 1107-1119 (2021)
Microbial Biotechnology, Vol 14, Iss 3, Pp 1107-1119 (2021)
Summary We developed a cost sensitive isotope labelling procedure using a fed‐batch fermentation method and tested its efficiency producing the 15N‐, 13C‐ and 15N/13C‐labelled variants of an amyloidogenic miniprotein (E5: EEEAVRLYIQWLKEGGPSSG
Autor:
Zsolt Gulyás, Blanka Moncsek, Kamirán Áron Hamow, Pál Stráner, Eszter Badics, Norbert Incze, Éva Darkó, Valéria Nagy, András Perczel, László Kovács, Vilmos Soós
Carotenoids are colourful isoprenoids that contribute to a variety of physiological processes in plants. They also function as biosynthesis precursors of abscisic acid (ABA) and strigolactones (SLs). SL biosynthesis starts with the enzymatic conversi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97bd7bedc63d5f107619dee18685136a
https://doi.org/10.1101/2022.04.06.487258
https://doi.org/10.1101/2022.04.06.487258
The extracellular domain of the glucagon-like peptide-1 receptor, GLP-1R, is responsible for the binding of GLP-1, and a handful of additional agonists (such as exenatide, lixisenatide, and liraglutide) used daily for treating type II diabetes mellit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d806f9a3d5094e6bf39988b701dc363
https://doi.org/10.1039/D2RA02784D
https://doi.org/10.1039/D2RA02784D
Publikováno v:
Current Protein & Peptide Science. 17:147-155
By using two different synthetic techniques several polypeptides interacting with Class B type G-protein coupled receptors were prepared. These polypeptides of different lengths (20 ≤ amino acids ≤ 40), structural and aggregation properties, were