Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Pál Pacher"'
Autor:
Zoltán V. Varga, Márton Pipicz, Júlia A. Baán, Tamás Baranyai, Gábor Koncsos, Przemyslaw Leszek, Mariusz Kuśmierczyk, Fátima Sánchez-Cabo, Pablo García-Pavía, Gábor J. Brenner, Zoltán Giricz, Tamás Csont, Luca Mendler, Enrique Lara-Pezzi, Pál Pacher, Péter Ferdinandy
Publikováno v:
Frontiers in Physiology, Vol 8 (2017)
Increased oxidative stress is a major contributor to the development and progression of heart failure, however, our knowledge on the role of the distinct NADPH oxidase (NOX) isoenzymes, especially on NOX4 is controversial. Therefore, we aimed to char
Externí odkaz:
https://doaj.org/article/77dab2edf454413e93c231c8ce8b47ad
Autor:
Csaba Imre Szalay, Katalin Erdélyi, Gábor Kökény, Enikő Lajtár, Mária Godó, Csaba Révész, Tamás Kaucsár, Norbert Kiss, Márta Sárközy, Tamás Csont, Tibor Krenács, Gábor Szénási, Pál Pacher, Péter Hamar
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0127090 (2015)
Chronic renal fibrosis is the final common pathway of end stage renal disease caused by glomerular or tubular pathologies. Genetic background has a strong influence on the progression of chronic renal fibrosis. We recently found that Rowett black hoo
Externí odkaz:
https://doaj.org/article/3beb17f1760d435780425e6bfbb74788
Autor:
András Iring, Éva Ruisanchez, Miriam Leszl-Ishiguro, Béla Horváth, Rita Benkő, Zsombor Lacza, Zoltán Járai, Péter Sándor, Vincenzo Di Marzo, Pál Pacher, Zoltán Benyó
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53390 (2013)
Endocannabinoids are among the most intensively studied lipid mediators of cardiovascular functions. In the present study the effects of decreased and increased activity of the endocannabinoid system (achieved by cannabinoid-1 (CB1) receptor blockade
Externí odkaz:
https://doaj.org/article/832916b4d8b04438b0b0894236d63b75
Autor:
Balázs Csóka, Zoltán H Németh, Partha Mukhopadhyay, Zoltán Spolarics, Mohanraj Rajesh, Stephanie Federici, Edwin A Deitch, Sándor Bátkai, Pál Pacher, György Haskó
Publikováno v:
PLoS ONE, Vol 4, Iss 7, p e6409 (2009)
BACKGROUND:Sepsis is a major healthcare problem and current estimates suggest that the incidence of sepsis is approximately 750,000 annually. Sepsis is caused by an inability of the immune system to eliminate invading pathogens. It was recently propo
Externí odkaz:
https://doaj.org/article/00cf65ea0c4f4255ba7d4f9cd06718c3
Autor:
Marianna Lovászi, Zoltán H. Németh, Pál Pacher, William C. Gause, Gebhard Wagener, György Haskó
Publikováno v:
Purinergic Signalling. 18:345-358
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c71ef66f28f40b18483cef0c5f23961d
https://doi.org/10.1007/s11302-022-09884-0
https://doi.org/10.1007/s11302-022-09884-0
Extracellular adenosine is a biologically active signaling molecule that accumulates at sites of metabolic stress in sepsis. Extracellular adenosine has potent immunosuppressive effects by binding to and activating G protein-coupled A2A adenosine rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::048aff60bf49fb4c4cc3d3c880769f79
https://doi.org/10.21203/rs.3.rs-1601722/v1
https://doi.org/10.21203/rs.3.rs-1601722/v1
Autor:
Marianna, Lovászi, Zoltán H, Németh, Pál, Pacher, William C, Gause, Gebhard, Wagener, György, Haskó
Publikováno v:
Purinergic Signal
Extracellular adenosine is a biologically active signaling molecule that accumulates at sites of metabolic stress in sepsis. Extracellular adenosine has potent immunosuppressive effects by binding to and activating G protein-coupled A(2A) adenosine r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fa4feb0139627a88037c73a5b5b99ac1
https://pubmed.ncbi.nlm.nih.gov/35838900
https://pubmed.ncbi.nlm.nih.gov/35838900
Autor:
Cassandra E. Bradley, Emma Fletcher, Trevor Wilkinson, Andrew Ring, Lucas Cardona Ferrer, Dimitrios Miserlis, Pal Pacher, Panagiotis Koutakis
Publikováno v:
EXCLI Journal : Experimental and Clinical Sciences, Vol 23, Pp 523-533 (2024)
Peripheral artery disease (PAD) is an atherosclerotic disease impacting over 200 million individuals and the prevalence increases with age. PAD occurs when plaque builds up within the peripheral arteries, leading to reduced blood flow and oxygen supp
Externí odkaz:
https://doaj.org/article/8f606c8942c544229b58f02dd5a81979
Autor:
Ming Jiang, Mirjam C. W. Huizenga, Jonah L. Wirt, Janos Paloczi, Avand Amedi, Richard J. B. H. N. van den Berg, Joerg Benz, Ludovic Collin, Hui Deng, Xinyu Di, Wouter F. Driever, Bogdan I. Florea, Uwe Grether, Antonius P. A. Janssen, Thomas Hankemeier, Laura H. Heitman, Tsang-Wai Lam, Florian Mohr, Anto Pavlovic, Iris Ruf, Helma van den Hurk, Anna F. Stevens, Daan van der Vliet, Tom van der Wel, Matthias B. Wittwer, Constant A. A. van Boeckel, Pal Pacher, Andrea G. Hohmann, Mario van der Stelt
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Monoacylglycerol lipase (MAGL) regulates endocannabinoid 2-arachidonoylglycerol (2-AG) and eicosanoid signalling. MAGL inhibition provides therapeutic opportunities but clinical potential is limited by central nervous system (CNS)-mediated s
Externí odkaz:
https://doaj.org/article/fdb22352db0b4e3798c8149c29653a5f
Autor:
Taha Kelestemur, Zoltán H. Németh, Pal Pacher, Jennet Beesley, Simon C. Robson, Holger K. Eltzschig, György Haskó
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-12 (2023)
Abstract Background Trauma and a subsequent hemorrhagic shock (T/HS) result in insufficient oxygen delivery to tissues and multiple organ failure. Extracellular adenosine, which is a product of the extracellular degradation of adenosine 5’ triphosp
Externí odkaz:
https://doaj.org/article/4238d3f9218f4b0c981e481ab1ebd3be