Zobrazeno 1 - 10
of 190
pro vyhledávání: '"Pál, Herczegh"'
Autor:
Eszter Boglárka Lőrincz, Gergely Tóth, Júlia Spolárics, Mihály Herczeg, Jan Hodek, István Zupkó, Renáta Minorics, Dorottya Ádám, Attila Oláh, Christos C. Zouboulis, Jan Weber, Lajos Nagy, Eszter Ostorházi, Ildikó Bácskay, Anikó Borbás, Pál Herczegh, Ilona Bereczki
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-20 (2023)
Abstract (−)-Cannabidiol (CBD) and (−)-cannabigerol (CBG) are two major non-psychotropic phytocannabinoids that have many beneficial biological properties. However, due to their low water solubility and prominent first-pass metabolism, their oral
Externí odkaz:
https://doaj.org/article/5a9a372dc9b844a19bbb1a3fff919b53
Autor:
Miklós Bege, Vigyasa Singh, Neha Sharma, Nóra Debreczeni, Ilona Bereczki, Poonam, Pál Herczegh, Brijesh Rathi, Shailja Singh, Anikó Borbás
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Drug-resistant Plasmodium falciparum (Pf) infections are a major burden on the population and the healthcare system. The establishment of Pf resistance to most existing antimalarial therapies has complicated the problem, and the emergence of
Externí odkaz:
https://doaj.org/article/78613e49621e493cae7f038739078da0
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Gram-negative bacteria possess intrinsic resistance to glycopeptide antibiotics so these important antibacterial medications are only suitable for the treatment of Gram-positive bacterial infections. At the same time, polymyxins are peptide
Externí odkaz:
https://doaj.org/article/56654604adc14062ac8524ad541391e1
Autor:
Ilona Bereczki, Vladimir Vimberg, Eszter Lőrincz, Henrietta Papp, Lajos Nagy, Sándor Kéki, Gyula Batta, Ana Mitrović, Janko Kos, Áron Zsigmond, István Hajdú, Zsolt Lőrincz, Dávid Bajusz, László Petri, Jan Hodek, Ferenc Jakab, György M. Keserű, Jan Weber, Lieve Naesens, Pál Herczegh, Anikó Borbás
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Patients infected with SARS-CoV-2 risk co-infection with Gram-positive bacteria, which severely affects their prognosis. Antimicrobial drugs with dual antiviral and antibacterial activity would be very useful in this setting. Although glycop
Externí odkaz:
https://doaj.org/article/91f0f017bd784a0087174f5750d3561a
Autor:
Eszter Boglárka Lőrincz, Mihály Herczeg, Josef Houser, Martina Rievajová, Ákos Kuki, Lenka Malinovská, Lieve Naesens, Michaela Wimmerová, Anikó Borbás, Pál Herczegh, Ilona Bereczki
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 24, p 17268 (2023)
In the shadow of SARS-CoV-2, influenza seems to be an innocent virus, although new zoonotic influenza viruses evolved by mutations may lead to severe pandemics. According to WHO, there is an urgent need for better antiviral drugs. Blocking viral hema
Externí odkaz:
https://doaj.org/article/ab384dde763d4113b4a3247c043b338d
Autor:
Kitti Szőke, Richárd Kajtár, Alexandra Gyöngyösi, Attila Czompa, Adina Fésüs, Eszter Boglárka Lőrincz, Ferenc Dániel Petróczi, Pál Herczegh, István Bak, Anikó Borbás, Ilona Bereczki, István Lekli
Publikováno v:
Antioxidants, Vol 12, Iss 9, p 1714 (2023)
Cannabidiol (CBD) is a nonpsychoactive phytocannabinoid that can be found in Cannabis sativa and possesses numerous pharmacological effects. Due to these promising effects, CBD can be used in a wide variety of diseases, for instance cardiovascular di
Externí odkaz:
https://doaj.org/article/cc0dbbd58ec44ab1bb7fbc810dc3585b
Autor:
Miklós Bege, Mihály Herczeg, Ilona Bereczki, Nóra Debreczeni, Attila Bényei, Pál Herczegh, Anikó Borbás
Publikováno v:
Organic & Biomolecular Chemistry. 21:2213-2219
Conformationally constrained tricyclic morpholino-nucleosides containing three new chirality centers were prepared with full stereoselectivity, through two consecutive hemiaminal-imidazolidine cascade reactions.
Autor:
Ilona Bereczki, Zsolt Szűcs, Gyula Batta, Tamás Milán Nagy, Eszter Ostorházi, Katalin E. Kövér, Anikó Borbás, Pál Herczegh
Publikováno v:
Pharmaceuticals, Vol 15, Iss 1, p 77 (2022)
Various dimeric derivatives of the glycopeptide antibiotic teicoplanin were prepared with the aim of increasing the activity of the parent compound against glycopeptide-resistant bacteria, primarily vancomycin-resistant enterococci. Starting from tei
Externí odkaz:
https://doaj.org/article/3da40169d3d543cc84a3002057ef95a6
Autor:
Vladimir Vimberg, Leona Zieglerova, Aninda Mazumdar, Zsolt Szűcs, Aniko Borbás, Pál Herczegh, Gabriela Balikova Novotna
Publikováno v:
Pharmaceuticals, Vol 14, Iss 11, p 1182 (2021)
The increase in antibiotic resistance among Gram-positive bacteria underscores the urgent need to develop new antibiotics. New antibiotics should target actively growing susceptible bacteria that are resistant to clinically accepted antibiotics inclu
Externí odkaz:
https://doaj.org/article/17c1c0e3cb234f2b884059fda98a0fcd
Autor:
Son Thai Le, Dávid Páll, Erzsébet Rőth, Tuyen Tran, Nóra Debreczeni, Miklós Bege, Ilona Bereczki, Eszter Ostorházi, Márton Milánkovits, Pál Herczegh, Anikó Borbás, Magdolna Csávás
Publikováno v:
Pharmaceutics, Vol 13, Iss 12, p 2028 (2021)
Pleuromutilin is a fungal diterpene natural product with antimicrobial properties, semisynthetic derivatives of which are used in veterinary and human medicine. The development of bacterial resistance to pleuromutilins is known to be very slow, which
Externí odkaz:
https://doaj.org/article/71d2511bcb4d41e2aea26fb92d907835