Zobrazeno 1 - 10
of 72
pro vyhledávání: '"P, Von Bossanyi"'
Publikováno v:
Journal of Neuro-Oncology. 53:1-11
PLK-1 (polo-like kinase) belongs to the family of serine/threonine kinases and is involved in spindle formation, centrosome cycles and chromosome segregation. Hence, the kinase is tightly linked to cell proliferation. We could detect immunohistochemi
Autor:
Elmar Kirches, Wolfram S. Kunz, Kirstin Winkler, M. Warich-Kirches, F. Wien, P. K. Bajaj, P. von Bossanyi, Knut Dietzmann, R. Szibor
Publikováno v:
Journal of Inherited Metabolic Disease. 21:400-408
The ratio of mtDNA and a nuclear reference gene was estimated by Southern blotting in the skeletal muscle DNA of a 3-year-old girl who suffered from congenital brain damage, focal epilepsy, hepatomegaly, malabsorption syndrome and severe myopathy. Th
Autor:
Andrey V. Kuznetsov, P. von Bossanyi, Kirstin Winkler, Knut Dietzmann, Falk R. Wiedemann, Wolfram S. Kunz
Publikováno v:
Molecular and Cellular Biochemistry. 183:87-96
The mdx mouse, an animal model of the Duchenne muscular dystrophy, was used for the investigation of changes in mitochondrial function associated with dystrophin deficiency. Enzymatic analysis of skeletal muscle showed an approximately 50% decrease i
Autor:
E, Kirches, J, Grunewald, P, von Bossanyi, R, Szibor, I, Plate, S, Krüger, M, Warich-Kirches, K, Dietzmann
Publikováno v:
Clinical neuropathology. 20(1)
The expression of metalloproteinases was evaluated in a series of 12 meningiomas of various histological subtypes including 3 meningotheliomatous, 3 fibroblastic, 4 transitional and one psammomatous meningioma (WHO grade I) as well as one anaplastic
Autor:
E, Kirches, K, Winkler, S, Vielhaber, M, Michael, M, Warich-Kirches, P, von Bossanyi, I, Plate, W S, Kunz, R, Szibor, H, Feistner, K, Dietzmann
Publikováno v:
Pathobiology : journal of immunopathology, molecular and cellular biology. 67(4)
We discovered a new homoplasmic mutation in the mitochondrial cysteine tRNA of a 60-year-old Caucasian male suffering from asymmetrical pure lower motor neuron disease (MND) and temporal lobe epilepsy (TLE). Furthermore, titrations with Amytal, an in
Publikováno v:
Clinical neuropathology. 18(4)
The aim of the study was to analyze the intrauterine and postpartal effects of Chloroquine on the dendritic maturation in the hippocampus and on the expression of GABA within hippocampal interneurons of the stratum moleculare. Fifty-nine brains of ra
Autor:
E, Kirches, C, Scherlach, P, von Bossanyi, T, Schneider, R, Szibor, E, Kutz, M, Warich-Kirches, K, Dietzmann
Publikováno v:
Clinical neuropathology. 18(1)
AIM, MATERIAL AND METHODS: Using RT-PCR and immunohistochemistry the expression of cytochrome P450 was evaluated in a series of 22 glioblastomas and 4 anaplastic astrocytomas (WHO grade III). Since rat liver P450 can catalyze the denitrosation of the
Publikováno v:
Molecular and cellular biochemistry. 183(1-2)
The mdx mouse, an animal model of the Duchenne muscular dystrophy, was used for the investigation of changes in mitochondrial function associated with dystrophin deficiency. Enzymatic analysis of skeletal muscle showed an approximately 50% decrease i
Publikováno v:
Acta neuropathologica. 94(6)
The expression of the drug resistance-related proteins glutathione S-transferases (GST) and P-glycoprotein (Pgp) was analyzed quantitatively in samples of 53 astrocytic gliomas (eight WHO grade 1, 11 WHO grade 2, 9 WHO grade 3 and 25 glioblastomas, W
Publikováno v:
Clinical neuropathology. 16(1)
104 N2-frozen samples from 33 astrocytic tumors previously untreated with cytotoxic drugs have been analyzed for the expression of p-glycoprotein transcripts (mdrl) by RT-PCR using beta2-microglobulin as an internal control. A remarkable variation wa