Zobrazeno 1 - 10
of 163
pro vyhledávání: '"P, Van Eerdewegh"'
Autor:
Margaret E. Brousseau, Ernst J. Schaefer, Josee Dupuis, Brenda Eustace, Paul Van Eerdewegh, Allison L. Goldkamp, Lisa M. Thurston, Michael G. FitzGerald, Diane Yasek-McKenna, Gilmore O'Neill, Gretchen P. Eberhart, Barbara Weiffenbach, Jose M. Ordovas, Mason W. Freeman, Robert H. Brown, Jr., Jessie Z. Gu
Publikováno v:
Journal of Lipid Research, Vol 41, Iss 3, Pp 433-441 (2000)
Abstract: Tangier disease (TD) is an autosomal co-dominant disorder in which homozygotes have a marked deficiency of high density lipoprotein (HDL) cholesterol and, in some cases, peripheral neuropathy and premature coronary heart disease (CHD). Homo
Externí odkaz:
https://doaj.org/article/fd9cecdea07e49dd948151a1774c02e1
Autor:
Xiaolan Hu, Eve Pickering, Yingxue Cathy Liu, Stephanie Hall, Helene Fournier, Elyse Katz, Bryan Dechairo, Sally John, Paul Van Eerdewegh, Holly Soares, Alzheimer's Disease Neuroimaging Initiative
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e16616 (2011)
Recent GWAS studies focused on uncovering novel genetic loci related to AD have revealed associations with variants near CLU, CR1, PICALM and BIN1. In this study, we conducted a genome-wide association study in an independent set of 1034 cases and 11
Externí odkaz:
https://doaj.org/article/72475f61252345a385e571111b90b02c
Autor:
Keith Tim P, Giese Heidi, Turenne Laura, Del Mastro Richard G, Van Eerdewegh Paul, May Klaus JW, Little Randall D
Publikováno v:
BMC Medical Genetics, Vol 8, Iss 1, p 46 (2007)
Abstract Background ADAM33 has been identified as an asthma-associated gene in an out-bred population. Genetic studies suggested that the functional role of this metalloprotease was in airway remodeling. However, the mechanistic roles of the disease-
Externí odkaz:
https://doaj.org/article/ddf88ff5ef5d4d2d8b37966e78ddc605
Publikováno v:
BMC Genetics, Vol 5, Iss 1, p 32 (2004)
Abstract Background Genome-wide association studies for complex diseases will produce genotypes on hundreds of thousands of single nucleotide polymorphisms (SNPs). A logical first approach to dealing with massive numbers of SNPs is to use some test t
Externí odkaz:
https://doaj.org/article/3654b49645104a26aa9eff41c1fb07a2
Autor:
Shu Ye, P. Van Eerdewegh, Tim Keith, Sheila J. Barton, Brooke Hayward, Ian Sayers, Stephen T. Holgate, Bianca Beghe, J. B. Clough, Anthony P. Sampson, S. Rorke, John W. Holloway
Publikováno v:
Thorax. 58:417-424
Background: LTC4 synthase is essential for the production of cysteinyl leukotrienes (Cys-LT), critical mediators in asthma. We have identified a novel promoter polymorphism at position -1072 (G/A) and a -444 (A/C) polymorphism has previously been rep
Autor:
Shantia Shears, John I. Nurnberger, Bernice Porjesz, K. K. Bucholz, William Wu, C. R. Cloninger, Candice Crose, Howard J. Edenberg, Jinghua Zhao, Alison Goate, Tatiana Foroud, Raymond R. Crowe, Chris Willig, Ting-Kai Li, P. Van Eerdewegh, Victor Hesselbrock, John P. Rice, Kristie Carr, P. M. Conneally, Thomas R. Przybeck, Henri Begleiter, Jay A. Tischfield, M. Schuckit, Theodore Reich, John Blangero, Laura Almasy
Publikováno v:
American Journal of Medical Genetics. 81:313-317
A genome-wide scan between normal human personality traits and a set of genetic markers at an average interval of 13 centimorgans was carried out in 758 pairs of siblings in 177 nuclear families of alcoholics. Personality traits were measured by the
Autor:
Marc A. Schuckit, Theodore Reich, John I. Nurnberger, Lance O. Bauer, John Blangero, John W. Rohrbaugh, Raymond R. Crowe, Tatiana Foroud, Sean O'Connor, Floyd E. Bloom, Samuel Kuperman, P. Van Eerdewegh, David B. Chorlian, Victor Hesselbrock, John P. Rice, Howard J. Edenberg, Bernice Porjesz, Henri Begleiter, Alison Goate, Ting-Kai Li, Laura Almasy, P. M. Conneally, Robert C. Cloninger, John Polich
Publikováno v:
Electroencephalography and Clinical Neurophysiology/Evoked Potentials Section. 108:244-250
The P3 event-related brain potential (ERP) is a positive-going voltage change of scalp-recorded electroencephalographic activity that occurs between 300-500 ms after stimulus onset. It is elicited when a stimulus is perceived, memory operations are e
Autor:
Daniel E. Weeks, Mark H. Skolnick, Stuart Sherman, S.W. Guo, R.F. Kefford, Rudolph E. Tanzi, Erik W. Thompson, S. Williams-Blangero, Jack T. Rogers, Nancy R. Mendell, R.R. Frants, P.M. Stewart, B. McKnight, G.M. Cox, Darlene R. Goldstein, J. Ott, G.E. Bonney, Sarah R. Wilson, C.E. Aston, D.L. Duffy, Terence P. Speed, N. Risch, B.S. Weir, R.A. Lewis, G.P. Vogler, M. Frigge, M.A. Province, Gary A. Chase, A. Kong, D.E. Goldgar, A.C. Warren, C.M. Lewis, C. Tierney, Susan E. Hodge, N.G. Martin, Aravinda Chakravarti, A.P. Round, K.K. Amfoh, Deborah A. Meyers, D.R. Cox, H.M. Shaw, J.D. Elashoff, C.I. Amos, Katheleen Gardiner, Lisa A. Cannon-Albright, H. Yuan, C. Murigande, G.M. Petersen, D.F. Easton, M.B. Risman, Lynn R. Goldin, S.J. Bale, A.M. Macdonald, P. Van Eerdewegh, E.L. Harris, Sherri J. Bale, David Patterson, P. Watkms, Nan Rochberg, M.A. Tucker, E.B. Claus, Ellen M. Wijsman, J.D. Terwilliger, S. Lawrence, P. Szolovits, N. Risen, C.M. Kammerer, Stylianos E. Antonarakis, J.E. Reefer, Veronica J. Vieland, Timothy Bishop, G.P. Crockford, F.M. Demenais, Rudy Guerra, M.H. Skolnick, M.W. Piepkorn, S. Moldin, James A. Trofatter, N. Cox, L.A. Cupples, H. Blossey, J. Blangero, L.A. Farrer, V.L. Prenger, I.B. Borecki, J.A. Donald, N.A. Gruis, P. M. Conneally, L.R. Weitkamp, Terri H. Beaty, L.J. Meyer, B.G. Mellen, T.M. King, B. Towne, A.E. Laing, Richard H. Myers, J.J. Zone, P. Green, L.W. Konigsberg, D.T. Bishop, Rita M. Cantor, Chad Haynes, Joan E. Bailey-Wilson, Margaret A. Pericak-Vance, M. Boehnke, T.E. Dobbins, C.T. Falk, N. Morton, J.A. Salmon, S.L. Sherman, Jonathan Haines, W. Bergman, Mary Sara McPeek, L. Giuffra, R. Neuman, N.E. Maestri, David A. Greenberg, James F. Gusella, Maria Martinez, T. Rice, W.H. Wong, B.A.J. Ponder, W.H. McCarthy, Nancy S. Wexler, T. Lehner, M.C. Speer, A. Chakravarti, C.R. Colyer, J.K. Rivers, B.J.B. Keats, A.M. Goldstein, David R. Cox, Jean W. MacCluer, D.C. Thomas
Publikováno v:
Cytogenetic and Genome Research. 59:234-240
Publikováno v:
Cytogenetic and Genome Research. 59:214-216
Autor:
M E, Brousseau, E J, Schaefer, J, Dupuis, B, Eustace, P, Van Eerdewegh, A L, Goldkamp, L M, Thurston, M G, FitzGerald, D, Yasek-McKenna, G, O'Neill, G P, Eberhart, B, Weiffenbach, J M, Ordovas, M W, Freeman, R H, Brown, J Z, Gu
Publikováno v:
Journal of lipid research. 41(3)
Tangier disease (TD) is an autosomal co-dominant disorder in which homozygotes have a marked deficiency of high density lipoprotein (HDL) cholesterol and, in some cases, peripheral neuropathy and premature coronary heart disease (CHD). Homozygotes ar