Výsledky vyhledávání

Akademický článek

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Akademický článek

Comparison of iPSC-derived human intestinal epithelial cells with Caco-2 cells and human in vivo data after exposure to Lactiplantibacillus plantarum WCFS1

Autor: Aafke W. F. Janssen, Benthe van der Lugt, Loes P. M. Duivenvoorde, Arjan Paul Vos, Shanna Bastiaan-Net, Monic M. M. Tomassen, Janine A. C. Verbokkem, Emmie Blok-Heimerikx, Guido J. E. J. Hooiveld, Peter van Baarlen, Laurent Ferrier, Meike van der Zande

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)

Abstract To investigate intestinal health and its potential disruptors in vitro, representative models are required. Human induced pluripotent stem cell (hiPSC)-derived intestinal epithelial cells (IECs) more closely resemble the in vivo intestinal t

Externí odkaz: https://doaj.org/article/e6b1c437d55948e69c7b0d58c6cc1e9e

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

Rice-derived arabinoxylan fibers are particle size-dependent inducers of trained immunity in a human macrophage-intestinal epithelial cell co-culture model

Autor: Bart G.J. Moerings, Suzanne Abbring, Monic M.M. Tomassen, Henk A. Schols, Renger F. Witkamp, Klaske van Norren, Coen Govers, Jeroen van Bergenhenegouwen, Jurriaan J. Mes

Publikováno v: Current Research in Food Science, Vol 8, Iss , Pp 100666- (2024)

Arabinoxylans have been identified for a wide range of purported health-promoting applications, primarily attributed to its immunomodulatory effects. Previously, we have reported the ability of arabinoxylans to induce non-specific memory in innate im

Externí odkaz: https://doaj.org/article/9441439d03244325a32775f2aa9f4e8e

Zobrazit plný text záznamu

Akademický článek

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Akademický článek

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Akademický článek

Dietary fat induced chylomicron-mediated LPS translocation in a bicameral Caco-2cell model

Autor: Monic M. M. Tomassen, Coen Govers, A. Paul Vos, Nicole J. W. de Wit

Publikováno v: Lipids in Health and Disease, Vol 22, Iss 1, Pp 1-12 (2023)

Abstract Background There is increasing evidence that dietary fat, especially saturated fat, promotes the translocation of lipopolysaccharide (LPS) via chylomicron production in the gut. Chylomicrons can subsequently transport LPS to other parts of t

Externí odkaz: https://doaj.org/article/f3b17723ba164df5845899874bd3d3ee

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

Amyloid-β and APOE genotype predict memory decline in cognitively unimpaired older individuals independently of Alzheimer’s disease polygenic risk score

Autor: Jori Tomassen, Anouk den Braber, Sven J. van der Lee, Lianne M. Reus, Elles Konijnenberg, Stephen F. Carter, Maqsood Yaqub, Bart N.M. van Berckel, Lyduine E. Collij, Dorret I. Boomsma, Eco J.C. de Geus, Philip Scheltens, Karl Herholz, Betty M. Tijms, Pieter Jelle Visser

Publikováno v: BMC Neurology, Vol 22, Iss 1, Pp 1-11 (2022)

Abstract Background: What combination of risk factors for Alzheimer’s disease (AD) are most predictive of cognitive decline in cognitively unimpaired individuals remains largely unclear. We studied associations between APOE genotype, AD-Polygenic R

Externí odkaz: https://doaj.org/article/de2470f34ab8427f961bab5f7eb68c5e

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

Home-based intensive treatment of chronic radiation-associated dysphagia in head and neck cancer survivors (HIT-CRAD trial)

Autor: Hanne Massonet, Ann Goeleven, Leen Van den Steen, Alice Vergauwen, Margot Baudelet, Gilles Van Haesendonck, Olivier Vanderveken, Heleen Bollen, Lisette van der Molen, Fréderic Duprez, Peter Tomassen, Sandra Nuyts, Gwen Van Nuffelen

Publikováno v: Trials, Vol 23, Iss 1, Pp 1-15 (2022)

Abstract Background Chronic radiation-associated dysphagia (C-RAD) is considered to be one of the most severe functional impairments in head and neck cancer survivors treated with radiation (RT) or chemoradiation (CRT). Given the major impact of thes

Externí odkaz: https://doaj.org/article/0ee344c602c148dab84f4e763e330acc

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

The overall survival impact of prophylactic cranial irradiation in limited-stage small-cell lung cancer: A systematic review and meta-analysis

Autor: Mathijs L. Tomassen, Jacquelien Pomp, Janneke van der Stap, Anne S.R. van Lindert, Max Peters, José S.A. Belderbos, Dirk K.M. De Ruysscher, Steven H. Lin, Joost J.C. Verhoeff, Peter S.N. van Rossum

Publikováno v: Clinical and Translational Radiation Oncology, Vol 33, Iss , Pp 145-152 (2022)

Background: Prophylactic cranial irradiation (PCI) for limited-stage small-cell lung cancer (LS-SCLC) patients has become more controversial. Since the publication of the systematic review by Aupérin et al. in 1999, no randomized controlled trials r

Externí odkaz: https://doaj.org/article/6248a69e1fe54b6c8437480ee66ed65a

Zobrazit plný text záznamu

Akademický článek

Setting up a Governance Framework for Secondary Use of Routine Health Data in Nursing Homes: Development Study Using Qualitative Interviews

Autor: Yvonne Wieland-Jorna, Robert A Verheij, Anneke L Francke, Marit Tomassen, Max Houtzager, Karlijn J Joling, Mariska G Oosterveld-Vlug

Publikováno v: Journal of Medical Internet Research, Vol 25, p e38929 (2023)

BackgroundIn the nursing home sector, reusing routinely recorded data from electronic health records (EHRs) for knowledge development and quality improvement is still in its infancy. Trust in appropriate and responsible reuse is crucial for patients

Externí odkaz: https://doaj.org/article/9ab3dd458c4348b1aaf3f4f5f57749c1

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání