Zobrazeno 1 - 10
of 1 397
pro vyhledávání: '"P, Perlmann"'
Autor:
Ioannis Mantas, Ivana Flais, Yuvarani Masarapu, Tudor Ionescu, Solène Frapard, Felix Jung, Pierre Le Merre, Marcus Saarinen, Katarina Tiklova, Behzad Yaghmaeian Salmani, Linda Gillberg, Xiaoqun Zhang, Karima Chergui, Marie Carlén, Stefania Giacomello, Bastian Hengerer, Thomas Perlmann, Per Svenningsson
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract The Claustrum/dorsal endopiriform cortex complex (CLA) is an enigmatic brain region with extensive glutamatergic projections to multiple cortical areas. The transcription factor Nurr1 is highly expressed in the CLA, but its role in this regi
Externí odkaz:
https://doaj.org/article/f723ec46d21f4e5683d1ae7079739299
Autor:
Roberta Filograna, Jule Gerlach, Hae-Na Choi, Giovanni Rigoni, Michela Barbaro, Mikael Oscarson, Seungmin Lee, Katarina Tiklova, Markus Ringnér, Camilla Koolmeister, Rolf Wibom, Sara Riggare, Inger Nennesmo, Thomas Perlmann, Anna Wredenberg, Anna Wedell, Elisa Motori, Per Svenningsson, Nils-Göran Larsson
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-14 (2024)
Abstract Loss-of-function variants in the PRKN gene encoding the ubiquitin E3 ligase PARKIN cause autosomal recessive early-onset Parkinson’s disease (PD). Extensive in vitro and in vivo studies have reported that PARKIN is involved in multiple pat
Externí odkaz:
https://doaj.org/article/5261e43905b84e29a138f193cac7150a
Autor:
Lenara Gonçalves e Souza, Matheus Vilardo Lóes Moreira, Claudia Sayuri Saçaki, Eduardo Perlmann, Thacyana Beatriz Guimarães Lopes, Enio Ferreira, Juan Carlos Duque Moreno, Fabiano Montiani-Ferreira
Publikováno v:
Frontiers in Veterinary Science, Vol 11 (2024)
IntroductionCorneal ulcers are common lesions in both human and veterinary medicine. However, only a few studies have evaluated the efficacy of cross-linked hyaluronic acid (X-HA) eye drops on corneal wound healing. To our knowledge, this is the firs
Externí odkaz:
https://doaj.org/article/a3b1cb010b364e1495530950bb268011
Autor:
Behzad Yaghmaeian Salmani, Laura Lahti, Linda Gillberg, Jesper Kjaer Jacobsen, Ioannis Mantas, Per Svenningsson, Thomas Perlmann
Publikováno v:
eLife, Vol 12 (2024)
Midbrain dopamine (mDA) neurons comprise diverse cells with unique innervation targets and functions. This is illustrated by the selective sensitivity of mDA neurons of the substantia nigra compacta (SNc) in patients with Parkinson’s disease, while
Externí odkaz:
https://doaj.org/article/a86072f6a5cf4e218ec5d753716452f9
Autor:
Olga Skiteva, Ning Yao, Ioannis Mantas, Xiaoqun Zhang, Thomas Perlmann, Per Svenningsson, Karima Chergui
Publikováno v:
npj Parkinson's Disease, Vol 9, Iss 1, Pp 1-17 (2023)
Abstract In Parkinson’s disease (PD), axons of dopaminergic (DA) neurons in the substantia nigra pars compacta (SNc) degenerate before their cell bodies. Calcium influx during pacemaker firing might contribute to neuronal loss, but it is not known
Externí odkaz:
https://doaj.org/article/338bb60a80db4de0a3a853d91d4204b6
Akademický článek
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Akademický článek
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Akademický článek
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Autor:
Geórgia Bajer Fernandes de Freitas Porfirio, Elaine Souza Mello, Carinne Liesse Brunato, Eduardo Perlmann
Publikováno v:
Brazilian Journal of Veterinary Research and Animal Science, Vol 59 (2022)
Intraocular melanocytic neoplasms are common in dogs. However, the choroidal location of these neoplasms and their infiltration into the optic nerve are unusual. This paper reports a case of primary choroidal melanoma in a 12-year-old male Dachshund.
Externí odkaz:
https://doaj.org/article/319a063984984e17984307b6b543ae1a
Autor:
Daniel W. Hagey, Danijal Topcic, Nigel Kee, Florie Reynaud, Maria Bergsland, Thomas Perlmann, Jonas Muhr
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Sequential generation of layer-specific cortical neurons requires radial glial cells (RGCs) to balance self-renewal and commitment. Here the authors show that RGCs and lineage committed progenitors are defined by distinct cell cycle phases and CYCLIN
Externí odkaz:
https://doaj.org/article/233448a846a14b9a858b7a56acc46218