Zobrazeno 1 - 10
of 605
pro vyhledávání: '"P, Paavolainen"'
Autor:
Oona Paavolainen, Markus Peurla, Leena M. Koskinen, Jonna Pohjankukka, Kamyab Saberi, Ella Tammelin, Suvi-Riitta Sulander, Masi Valkonen, Larissa Mourao, Pia Boström, Nina Brück, Pekka Ruusuvuori, Colinda L.G.J. Scheele, Pauliina Hartiala, Emilia Peuhu
Publikováno v:
Cell Reports, Vol 43, Iss 10, Pp 114837- (2024)
Summary: The major lactiferous ducts of the human breast branch out and end at terminal ductal lobular units (TDLUs). Despite their functional and clinical importance, the three-dimensional (3D) architecture of TDLUs has remained undetermined. Our qu
Externí odkaz:
https://doaj.org/article/4fcb5c262ff1458f9cfbb71c980860cf
Publikováno v:
International Journal of Qualitative Studies on Health & Well-Being, Vol 19, Iss 1 (2024)
Eldercare workers experience higher levels of moral distress than other health and social care service workers. Moral distress is a psychological response to a morally challenging event. Very little is known about moral distress in the context of eld
Externí odkaz:
https://doaj.org/article/289b54408d454aa4a4fb2cd7be1a31be
Autor:
Michaela Feodoroff, Piia Mikkonen, Laura Turunen, Antti Hassinen, Lauri Paasonen, Lassi Paavolainen, Swapnil Potdar, Astrid Murumägi, Olli Kallioniemi, Vilja Pietiäinen
Publikováno v:
SLAS Discovery, Vol 28, Iss 4, Pp 138-148 (2023)
Central to the success of functional precision medicine of solid tumors is to perform drug testing of patient-derived cancer cells (PDCs) in tumor-mimicking ex vivo conditions. While high throughput (HT) drug screening methods have been well-establis
Externí odkaz:
https://doaj.org/article/bdeaf7bd18484cce910d529df5e05a9f
Publikováno v:
Työelämän tutkimus, Vol 21, Iss 3 (2023)
Tutkimus käsittelee vanhustyössä työskentelevien hoitajien moraalista toimijuutta moraalisissa ristiriitatilanteissa. Moraalisen toimijuuden rajoittumisen on esitetty olevan keskeinen tekijä eettisen kuormituksen synnyssä. Eettinen kuormitus on
Externí odkaz:
https://doaj.org/article/833beeb3a79349de8eb3bfc1dba70192
Akademický článek
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Autor:
Rim Bouslama, Vincent Dumont, Sonja Lindfors, Lassi Paavolainen, Jukka Tienari, Harry Nisen, Tuomas Mirtti, Moin A. Saleem, Daniel Gordin, Per-Henrik Groop, Shiro Suetsugu, Sanna Lehtonen
Publikováno v:
Cells, Vol 12, Iss 11, p 1487 (2023)
Changes in the dynamic architecture of podocytes, the glomerular epithelial cells, lead to kidney dysfunction. Previous studies on protein kinase C and casein kinase 2 substrates in neurons 2 (PACSIN2), a known regulator of endocytosis and cytoskelet
Externí odkaz:
https://doaj.org/article/051c46658c344b7d80aa86068b022ab4
Autor:
Abel Szkalisity, Filippo Piccinini, Attila Beleon, Tamas Balassa, Istvan Gergely Varga, Ede Migh, Csaba Molnar, Lassi Paavolainen, Sanna Timonen, Indranil Banerjee, Elina Ikonen, Yohei Yamauchi, Istvan Ando, Jaakko Peltonen, Vilja Pietiäinen, Viktor Honti, Peter Horvath
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
High-content screening prompted the development of software enabling discrete phenotypic analysis of single cells. Here, the authors show that supervised continuous machine learning can drive novel discoveries in diverse imaging experiments and prese
Externí odkaz:
https://doaj.org/article/f49f0d2d8b5f4b588375e657d0654bfa
Autor:
Hely Ollila, Mikko I. Mäyränpää, Lassi Paavolainen, Juuso Paajanen, Katja Välimäki, Eva Sutinen, Henrik Wolff, Jari Räsänen, Olli Kallioniemi, Marjukka Myllärniemi, Ilkka Ilonen, Teijo Pellinen
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundPleural mesothelioma (MPM) is an aggressive malignancy with an average patient survival of only 10 months. Interestingly, about 5%–10% of the patients survive remarkably longer. Prior studies have suggested that the tumor immune microenvi
Externí odkaz:
https://doaj.org/article/1bf39aa62b5648549ddcff3dbb3aafe5
Publikováno v:
IEEE Access, Vol 9, Pp 110085-110102 (2021)
The Ethereum blockchain is one of the most popular permissionless blockchains. A consequence of its popularity has been the growth of processing and data storage requirements for any node participating in the Ethereum blockchain network. For constrai
Externí odkaz:
https://doaj.org/article/ada1eca43a294b68ac68509d3efabdf9
Autor:
Santeri Paavolainen, Christopher Carr
Publikováno v:
IEEE Access, Vol 8, Pp 124339-124358 (2020)
Ethereum is a decentralized blockchain, known as being the second most popular public blockchain after Bitcoin. Since Ethereum is decentralised the canonical state is determined by the Ethereum network participants via a consensus mechanism without a
Externí odkaz:
https://doaj.org/article/6623ecf9aebb438dafd65d22878304cd