Graphene thermal infrared emitters integrated into silicon photonic waveguides

Autor: Negm, Nour, Zayouna, Sarah, Parhizkar, Shayan, Lin, Pen-Sheng, Huang, Po-Han, Suckow, Stephan, Schroeder, Stephan, De Luca, Eleonora, Briano, Floria Ottonello, Quellmalz, Arne, Duesberg, Georg S., Niklaus, Frank, Gylfason, Kristinn B., Lemme, Max C.

Cost-efficient and easily integrable broadband mid-infrared (mid-IR) sources would significantly enhance the application space of photonic integrated circuits (PICs). Thermal incandescent sources are superior to other common mid-IR emitters based on

Externí odkaz: http://arxiv.org/abs/2308.04046

A safe and potentiated multi-type HPV L2-E7 nanoparticle vaccine with combined prophylactic and therapeutic activity

Autor: Xueer Zhao, Yueru Zhang, Oscar Trejo-Cerro, Ecem Kaplan, Zhe Li, Femke Albertsboer, Neyla El Hammiri, Filipe Colaço Mariz, Lawrence Banks, Simone Ottonello, Martin Müller

Publikováno v: npj Vaccines, Vol 9, Iss 1, Pp 1-12 (2024)

Abstract Persistent infection with high-risk human papillomavirus (HPV) is widely recognized as the primary cause of cervical and other malignant cancers. There are six licensed prophylactic vaccines available against HPV, but none of them shows any

Externí odkaz: https://doaj.org/article/9217cc3d10dd4b0fa85b0fbc8c538da5

Inter-epitope spacer variation within polytopic L2-based human papillomavirus antigens affects immunogenicity

Autor: Yueru Zhang, Filipe Colaco Mariz, Peter Sehr, Gloria Spagnoli, Karl Moritz Koenig, Simay Çelikyürekli, Tim Kreuziger, Xueer Zhao, Angelo Bolchi, Simone Ottonello, Martin Müller

Publikováno v: npj Vaccines, Vol 9, Iss 1, Pp 1-11 (2024)

Abstract The human papillomavirus minor capsid protein L2 is being extensively explored in pre-clinical studies as an attractive vaccine antigen capable of inducing broad-spectrum prophylactic antibody responses. Recently, we have developed two HPV v

Externí odkaz: https://doaj.org/article/94f9ab3ef2084d6a85620c04ccf511de

Successful Versus Failed Transition From Controlled Ventilation to Pressure Support Ventilation in COVID-19 Patients: A Retrospective Cohort Study

Autor: Melisa Polo Friz, MD, Emanuele Rezoagli, MD, Bijan Safaee Fakhr, MD, Gaetano Florio, MD, Eleonora Carlesso, MS, Riccardo Giudici, MD, Clarissa Forlini, MD, Francesca Tardini, MD, Thomas Langer, MD, Matteo Laratta, MD, Giampaolo Casella, MD, Andrea Forastieri Molinari, MD, Alessandro Protti, MD, Maurizio Cecconi, MD, Luca Cabrini, MD, Emanuela Biagioni, MD, Angela Berselli, MD, Lucia Mirabella, MD, Tommaso Tonetti, MD, Edoardo De Robertis, MD, Domenico Luca Grieco, MD, Massimo Antonelli, MD, Giuseppe Citerio, MD, Roberto Fumagalli, MD, Giuseppe Foti, MD, Alberto Zanella, MD, Giacomo Grasselli, MD, Giacomo Bellani, MD, for the COVID-19 Lombardy ICU Network, Amedeo Guzzardella, Luigi Vivona, Vittorio Scaravilli, Sebastiano Colombo, Alessio Cacioppola, Matteo Brioni, Clarissa Forlini, Francesca Tardini, Thomas Langer, Matteo Laratta, Giampaolo Casella, Maria Marsili, Serena Stropeni, Valentina Cordolcini, Francesco Crimella, Alessandro Santini, Massimiliano Greco, Michele Ferrari, Giacomo Iapichino, Paolo Severgnini, Davide Maraggia, Dario Gasberti, Alessandro Motta, Irene Coloretti, Stefano Busani, Martina Tosi, Ilenia Gatto, Carlo Montalto, Alberto Biondo, Ziad Algamain, Valentina Alaimo, Livio Tullo, Francesco Paolo Padovano, Giacinto Pizzilli, Irene Cavalli, Rachele Simonte, Davide Valeri, Gennaro DePascale, Simone Carelli, Valentina Noseda, Giacomo Cimicchi, Gaia Ottonello, Rossano Ghedin, Francesco Giacalone, Tiziana Bove, Francesco Meroi, Sara Scapol, Laura Pistidda, Angela Muretti, Savino Spadaro, Gaetano Scaramuzzo, Gioconda Ferraro, Giuseppe Gagliardi, Giovanni Sabbatini, Angelo Pezzi, Gabriele Sales, Giorgia Montrucchio, Andrea Carsetti, Federico Longhini, Maria Vargas, Plinio Calligaro, Ilaria Mariani, Vanessa Zambelli, Beatrice Noè, Filippo Serra

Publikováno v: Critical Care Explorations, Vol 6, Iss 2, p e1039 (2024)

OBJECTIVES:. In patients with COVID-19 respiratory failure, controlled mechanical ventilation (CMV) is often necessary during the acute phases of the disease. Weaning from CMV to pressure support ventilation (PSV) is a key objective when the patient�

Externí odkaz: https://doaj.org/article/4b6ae8e021cf455fba1cf96f2a53600a

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