Zobrazeno 1 - 10
of 3 650
pro vyhledávání: '"P, Neurath"'
Autor:
Reyes Gámez-Belmonte, Yara Wagner, Mousumi Mahapatro, Ru Wang, Lena Erkert, Miguel González-Acera, Roodline Cineus, Saskia Hainbuch, Jay V. Patankar, David Voehringer, Ahmed N. Hegazy, Markus F. Neurath, Stefan Wirtz, Christoph Becker
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Gasdermin C is one of the least studied members of the gasdermin family of proteins, known for their critical involvement in pyroptosis and host defense. Furthermore, evidence for the role of Gasdermin C in the intestine is scarce and partly
Externí odkaz:
https://doaj.org/article/b1384b9584bd49dc96d572989f1a8151
Publikováno v:
Inflammatory Intestinal Diseases, Vol 9, Iss 1, Pp 220-228 (2024)
Background: Eosinophilic esophagitis is an increasing condition in industrialized countries. The etiology is still somewhat unclear. It was thought that it can be part of eosinophilic gastroenteritis but nowadays seen as a separate entity and thus mo
Externí odkaz:
https://doaj.org/article/4d47fd22ce00403591c639f1be4cec97
Autor:
Kim Wagner, Tanja M. Müller, Francesco Vitali, Sarah Fischer, Sophie Haberkamp, Rachel Rouse-Merkel, Raja Atreya, Markus F. Neurath, Sebastian Zundler
Publikováno v:
Therapeutic Advances in Gastroenterology, Vol 17 (2024)
Background: There is an increasing diversification in the treatment landscape for inflammatory bowel diseases (IBD) leading to therapeutic challenges that can only incompletely be covered by prospective randomized double-blind trials. Real-world obse
Externí odkaz:
https://doaj.org/article/0b42c0608bb84cbaa9ca90207dee411f
Autor:
Kenji Suzuki, Yukinori Sameshima, Junji Yokoyama, Shuji Terai, Hiroyuki Yoneyama, Raja Atreya, Markus F. Neurath, Toshifumi Hibi, Hitoshi Asakura
Publikováno v:
Inflammation and Regeneration, Vol 44, Iss 1, Pp 1-10 (2024)
Abstract Background Carbohydrate sulfotransferase 15 (CHST15) is an enzyme biosynthesizing matrix glycosaminoglycan that modulates tissue remodeling. We evaluated the efficacy of add-on submucosal injections of GUT-1, the RNA oligonucleotide inhibito
Externí odkaz:
https://doaj.org/article/4d12c4d2ddc145778e89ea6704cc7480
Autor:
Nicole Neurath, Marco Kesting
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Chronic inflammatory processes in the oral mucosa and periodontitis are common disorders caused by microflora and microbial biofilms. These factors activate both the innate and adaptive immune systems, leading to the production of pro-inflammatory cy
Externí odkaz:
https://doaj.org/article/cdd0ed4d61c84bdbb49e2538e1c3d408
Autor:
Maximilian Wiendl, Mark Dedden, Li-Juan Liu, Anna Schweda, Eva-Maria Paap, Karen A.-M. Ullrich, Leonie Hartmann, Luisa Wieser, Francesco Vitali, Imke Atreya, Tanja M. Müller, Claudia Günther, Raja Atreya, Markus F. Neurath, Sebastian Zundler
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Despite promising preclinical and earlier clinical data, a recent phase III trial on the anti-β7 integrin antibody etrolizumab in Crohn’s disease (CD) did not reach its primary endpoint. The mechanisms leading to this outcome are not well
Externí odkaz:
https://doaj.org/article/acac8322e2ba43b1966b2f33b0b17d77
Autor:
Imke Atreya, Markus F. Neurath
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-2 (2024)
Externí odkaz:
https://doaj.org/article/9b7a4414c12c48a99578d0cab4cdf16d
Autor:
Anna P. Träger, Josefine S. Günther, Roman Raming, Lars-Philip Paulus, Werner Lang, Alexander Meyer, Julius Kempf, Milenko Caranovic, Yi Li, Alexandra L. Wagner, Lina Tan, Vera Danko, Regina Trollmann, Joachim Woelfle, Daniel Klett, Markus F. Neurath, Adrian P. Regensburger, Markus Eckstein, Wolfgang Uter, Michael Uder, Yvonne Herrmann, Maximilian J. Waldner, Ferdinand Knieling, Ulrich Rother
Publikováno v:
Photoacoustics, Vol 35, Iss , Pp 100579- (2024)
Peripheral arterial disease (PAD) leads to chronic vascular occlusion and results in end organ damage in critically perfused limbs. There are currently no clinical methods available to determine the muscular damage induced by chronic mal-perfusion. T
Externí odkaz:
https://doaj.org/article/fb510c5fc8a546ee9909ffe916d51dd3
Autor:
Adrian P. Regensburger, Markus Eckstein, Matthias Wetzl, Roman Raming, Lars-Philip Paulus, Adrian Buehler, Emmanuel Nedoschill, Vera Danko, Jörg Jüngert, Alexandra L. Wagner, Alexander Schnell, Aline Rückel, Ulrich Rother, Oliver Rompel, Michael Uder, Arndt Hartmann, Markus F. Neurath, Joachim Woelfle, Maximilian J. Waldner, André Hoerning, Ferdinand Knieling
Publikováno v:
Photoacoustics, Vol 35, Iss , Pp 100578- (2024)
Multispectral optoacoustic tomography (MSOT) allows non-invasive molecular disease activity assessment in adults with inflammatory bowel disease (IBD). In this prospective pilot-study, we investigated, whether increased levels of MSOT haemoglobin par
Externí odkaz:
https://doaj.org/article/8aac55cc9b8d47b8968e97f185cb219a
Autor:
Francesco Vitali, Timo Rath, Entcho Klenske, Anna-Lena Vögele, Ingo Ganzleben, Sebastian Zundler, Deike Strobel, Carol Geppert, Arndt Hartmann, Markus F. Neurath, Raja Atreya
Publikováno v:
Therapeutic Advances in Gastroenterology, Vol 17 (2024)
Background: Effective management of patients with acute severe ulcerative colitis (ASUC) is a major challenge and there remains a paucity of available maintenance treatment options after efficacious cyclosporin induction therapy. Objectives: We inves
Externí odkaz:
https://doaj.org/article/6893d39668f04c80b05d2913832cad4b