Zobrazeno 1 - 10
of 821
pro vyhledávání: '"P, Nankivell"'
Autor:
Shephard, Adam J, Mahmood, Hanya, Raza, Shan E Ahmed, Araujo, Anna Luiza Damaceno, Santos-Silva, Alan Roger, Lopes, Marcio Ajudarte, Vargas, Pablo Agustin, McCombe, Kris, Craig, Stephanie, James, Jacqueline, Brooks, Jill, Nankivell, Paul, Mehanna, Hisham, Khurram, Syed Ali, Rajpoot, Nasir M
Oral epithelial dysplasia (OED) is a premalignant histopathological diagnosis given to lesions of the oral cavity. OED grading is subject to large inter/intra-rater variability, resulting in the under/over-treatment of patients. We developed a new Tr
Externí odkaz:
http://arxiv.org/abs/2311.05452
Autor:
Shephard, Adam J, Bashir, Raja Muhammad Saad, Mahmood, Hanya, Jahanifar, Mostafa, Minhas, Fayyaz, Raza, Shan E Ahmed, McCombe, Kris D, Craig, Stephanie G, James, Jacqueline, Brooks, Jill, Nankivell, Paul, Mehanna, Hisham, Khurram, Syed Ali, Rajpoot, Nasir M
Oral epithelial dysplasia (OED) is a premalignant histopathological diagnosis given to lesions of the oral cavity. Its grading suffers from significant inter-/intra- observer variability, and does not reliably predict malignancy progression, potentia
Externí odkaz:
http://arxiv.org/abs/2307.03757
Autor:
Adam J. Shephard, Raja Muhammad Saad Bashir, Hanya Mahmood, Mostafa Jahanifar, Fayyaz Minhas, Shan E. Ahmed Raza, Kris D. McCombe, Stephanie G. Craig, Jacqueline James, Jill Brooks, Paul Nankivell, Hisham Mehanna, Syed Ali Khurram, Nasir M. Rajpoot
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-12 (2024)
Abstract Oral epithelial dysplasia (OED) is a premalignant histopathological diagnosis given to lesions of the oral cavity. Its grading suffers from significant inter-/intra-observer variability, and does not reliably predict malignancy progression,
Externí odkaz:
https://doaj.org/article/b26574c2f4f740f0b49bb221663a5412
Autor:
Rouyan Chen, Lauren Sandeman, Victoria Nankivell, Joanne T. M. Tan, Mohammad Rashidi, Peter J. Psaltis, Gang Zheng, Christina Bursill, Robert A. McLaughlin, Jiawen Li
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Atherosclerosis is the build-up of fatty plaques within blood vessel walls, which can occlude the vessels and cause strokes or heart attacks. It gives rise to both structural and biomolecular changes in the vessel walls. Current single-modal
Externí odkaz:
https://doaj.org/article/4bae5d5a33d7421e8b8e67ef4038f830
Autor:
Hisham Mehanna, Piers Gaunt, Anthony Kong, Andrew Hartley, Paul Sanghera, Martin Forster, Mehmet Sen, Vinidh Paleri, Charles Fong, Dinos Geropantas, Devraj Srinivasan, Satya Garikipati, Rafael Moleron, Georgina Casswell, Eleanor Aynsley, Amy Ward, Lorcan O’Toole, Arafat Mirza, Charlotte Firth, Isla Humphreys, Tessa Fulton-Lieuw, Tom Roques, Paul Nankivell
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-17 (2024)
Abstract Background Patients with intermediate and high-risk oropharyngeal cancer (OPC) have poorer response to standard treatment and poorer overall survival compared to low-risk OPC. CompARE is designed to test alternative approaches to intensified
Externí odkaz:
https://doaj.org/article/330dec8870f14404b747cb77cc116ff3
Autor:
Karl F. B. Payne, Peter Brotherwood, Harini Suriyanarayanan, Jill M. Brooks, Nikolaos Batis, Andrew D. Beggs, Deena M. A. Gendoo, Hisham Mehanna, Paul Nankivell
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundAs circulating tumour DNA (ctDNA) liquid biopsy analysis is increasingly incorporated into modern oncological practice, establishing the impact of genomic intra-tumoural heterogeneity (ITH) upon data output is paramount. Despite advances in
Externí odkaz:
https://doaj.org/article/e05145d79eb243d7a8953e7b92d45ddb
Autor:
Janine Dretzke, Talhah Chaudri, Rishab Balaji, Hisham Mehanna, Paul Nankivell, David J. Moore, Members of the PETNECK2 Research Team ‐ in alphabetical order by first name
Publikováno v:
Cancer Medicine, Vol 12, Iss 18, Pp 19057-19071 (2023)
Abstract Background The traditional cancer follow‐up (FU) model for cancer survivors is by scheduled clinic appointments; however, this is not tailored to patient needs and is becoming unsustainable. Patient‐initiated follow‐up (PIFU) may be a
Externí odkaz:
https://doaj.org/article/ba02b590128545369c52b2e16323cd13
Autor:
Janine Dretzke, Ava Lorenc, Ada Adriano, Clare Herd, Hisham Mehanna, Paul Nankivell, David J. Moore, Members of the PETNECK2 Research Team ‐ in alphabetical order by first name
Publikováno v:
Cancer Medicine, Vol 12, Iss 15, Pp 16531-16547 (2023)
Abstract Background Current follow‐up models in cancer are seen to be unsustainable and inflexible, and there is growing interest in alternative models, such as patient‐initiated follow‐up (PIFU). It is therefore important to understand whether
Externí odkaz:
https://doaj.org/article/6aef62f6d40f4b6a93e8d19a213ace2d
Autor:
Shaban, Muhammad, Raza, Shan E Ahmed, Hassan, Mariam, Jamshed, Arif, Mushtaq, Sajid, Loya, Asif, Batis, Nikolaos, Brooks, Jill, Nankivell, Paul, Sharma, Neil, Robinson, Max, Mehanna, Hisham, Khurram, Syed Ali, Rajpoot, Nasir
The infiltration of T-lymphocytes in the stroma and tumour is an indication of an effective immune response against the tumour, resulting in better survival. In this study, our aim is to explore the prognostic significance of tumour-associated stroma
Externí odkaz:
http://arxiv.org/abs/2104.12862
Autor:
Hannah Simonds, Ruth Langley, Indranil Mallick, Peter Hoskin, Elizabeth Miles, Rozita Abdul Malik, Claire Murphy, Mahesh Parmar, Matthew Nankivell, Jeannette Parkes, Julie Torode, Issa Mohamad, Laurence Edward Court, Isabella Jacques, Mariana Kroiss, Sarbani Laskar, Yolande Lievens, Carol Roach, Barbara Vanderstraeten
Publikováno v:
BMJ Open, Vol 13, Iss 12 (2023)
Introduction Fifty per cent of patients with cancer require radiotherapy during their disease course, however, only 10%–40% of patients in low-income and middle-income countries (LMICs) have access to it. A shortfall in specialised workforce has be
Externí odkaz:
https://doaj.org/article/7e143e27867f4edaa860b190a5116af9