Zobrazeno 1 - 10
of 4 421
pro vyhledávání: '"P, Leder"'
Autor:
Lewis, Samantha M., Goulart, Dillon T., Barbosa, Mirelys Carcana, Leder, Alexander F., Sindhwad, Aarav M., Urdinaran, Isabella, van Bibber, Karl
Axions are a well-motivated dark matter candidate particle. Haloscopes aim to detect axions in the galactic halo by measuring the photon signal resulting from axions interacting with a strong magnetic field. Existing haloscopes are primarily targetin
Externí odkaz:
http://arxiv.org/abs/2408.03861
In this paper, we introduce a new optimization algorithm that is well suited for solving parameter estimation problems. We call our new method cubic regularized Newton with affine scaling (CRNAS). In contrast to so-called first-order methods which re
Externí odkaz:
http://arxiv.org/abs/2407.04235
Autor:
Myklebust, Even Moa, Frigessi, Arnoldo, Schjesvold, Fredrik, Foo, Jasmine, Leder, Kevin, Köhn-Luque, Alvaro
Predicting cancer dynamics under treatment is challenging due to high inter-patient heterogeneity, lack of predictive biomarkers, and sparse and noisy longitudinal data. Mathematical models can summarize cancer dynamics by a few interpretable paramet
Externí odkaz:
http://arxiv.org/abs/2405.14508
In this study, we develop consistent estimators for key parameters that govern the dynamics of tumor cell populations when subjected to pharmacological treatments. While these treatments often lead to an initial reduction in the abundance of drug-sen
Externí odkaz:
http://arxiv.org/abs/2403.13081
The site frequency spectrum (SFS) is a widely used summary statistic of genomic data. Motivated by recent evidence for the role of neutral evolution in cancer, we investigate the SFS of neutral mutations in an exponentially growing population. Using
Externí odkaz:
http://arxiv.org/abs/2307.03346
Autor:
Jan Mikuni, Blanca T. M. Spee, Gaia Forlani, Helmut Leder, Frank Scharnowski, Koyo Nakamura, Katsumi Watanabe, Hideaki Kawabata, Matthew Pelowski, David Steyrl
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract In empirical art research, understanding how viewers judge visual artworks as beautiful is often explored through the study of attributes—specific inherent characteristics or artwork features such as color, complexity, and emotional expres
Externí odkaz:
https://doaj.org/article/e2ffcfde25d7420191c3a2e392b635e1
Publikováno v:
ISPRS Annals of the Photogrammetry, Remote Sensing and Spatial Information Sciences, Vol X-4-W4-2024, Pp 43-48 (2024)
In the Split City area, with an air distance of approximately 18 km, the survey of land surface temperature (LST) and urban heat islands (UHI) was detected. It also shows how local geomorphology, especially the density of urban areas (especially dens
Externí odkaz:
https://doaj.org/article/92de29f6e8314e5380bbbd76d18470d3
Publikováno v:
Journal of Theoretical Biology, 568 (2023), 111497
Recent evidence suggests that nongenetic (epigenetic) mechanisms play an important role at all stages of cancer evolution. In many cancers, these mechanisms have been observed to induce dynamic switching between two or more cell states, which commonl
Externí odkaz:
http://arxiv.org/abs/2306.08096
Autor:
Kupferman, Raz, Leder, Roee
We solve a problem posed by Calabi more than 60 years ago, known as the Saint-Venant compatibility problem: Given a compact Riemannian manifold, generally with boundary, find a compatibility operator for Lie derivatives of the metric tensor. This pro
Externí odkaz:
http://arxiv.org/abs/2304.08977
Autor:
Wu, C., Gunnarsson, E. B., Myklebust, E. M., Köhn-Luque, A., Tadele, D. S., Enserink, J. M., Frigessi, A., Foo, J., Leder, K.
Tumor heterogeneity is a complex and widely recognized trait that poses significant challenges in developing effective cancer therapies. In particular, many tumors harbor a variety of subpopulations with distinct therapeutic response characteristics.
Externí odkaz:
http://arxiv.org/abs/2303.08245