Zobrazeno 1 - 10
of 229
pro vyhledávání: '"P, Katsel"'
Autor:
Vitaly Ryu, Anisa Gumerova, Funda Korkmaz, Seong Su Kang, Pavel Katsel, Sari Miyashita, Hasni Kannangara, Liam Cullen, Pokman Chan, TanChun Kuo, Ashley Padilla, Farhath Sultana, Soleil A Wizman, Natan Kramskiy, Samir Zaidi, Se-Min Kim, Maria I New, Clifford J Rosen, Ki A Goosens, Tal Frolinger, Vahram Haroutunian, Keqiang Ye, Daria Lizneva, Terry F Davies, Tony Yuen, Mone Zaidi
Publikováno v:
eLife, Vol 11 (2022)
There is increasing evidence that anterior pituitary hormones, traditionally thought to have unitary functions in regulating single endocrine targets, act on multiple somatic tissues, such as bone, fat, and liver. There is also emerging evidence for
Externí odkaz:
https://doaj.org/article/b3abe24a02a0498d998322980e6ccd74
Autor:
Noam D. Beckmann, Wei-Jye Lin, Minghui Wang, Ariella T. Cohain, Alexander W. Charney, Pei Wang, Weiping Ma, Ying-Chih Wang, Cheng Jiang, Mickael Audrain, Phillip H. Comella, Amanda K. Fakira, Siddharth P. Hariharan, Gillian M. Belbin, Kiran Girdhar, Allan I. Levey, Nicholas T. Seyfried, Eric B. Dammer, Duc Duong, James J. Lah, Jean-Vianney Haure-Mirande, Ben Shackleton, Tomas Fanutza, Robert Blitzer, Eimear Kenny, Jun Zhu, Vahram Haroutunian, Pavel Katsel, Sam Gandy, Zhidong Tu, Michelle E. Ehrlich, Bin Zhang, Stephen R. Salton, Eric E. Schadt
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-19 (2020)
To investigate the molecular foundation of sporadic Alzheimer’s disease (AD), Beckmann et al. constructed multiscale causal networks on a large human AD multi-omics dataset, detecting AD-associated networks and their top predicted regulator, VGF, w
Externí odkaz:
https://doaj.org/article/f3a49830ea0b40449d13d63b2ea4d0a8
Autor:
Young Jae Woo, Panos Roussos, Vahram Haroutunian, Pavel Katsel, Samuel Gandy, Eric E. Schadt, Jun Zhu, Alzheimer Disease Neuroimaging Initiative (ADNI)
Publikováno v:
BMC Medicine, Vol 18, Iss 1, Pp 1-17 (2020)
Abstract Background The human brain is complex and interconnected structurally. Brain connectome change is associated with Alzheimer’s disease (AD) and other neurodegenerative diseases. Genetics and genomics studies have identified molecular change
Externí odkaz:
https://doaj.org/article/b998240e90cd41099e57d781238a60cb
Autor:
Odile Poirel, Sébastien Mella, Catherine Videau, Lauriane Ramet, Maria Antonietta Davoli, Etienne Herzog, Pavel Katsel, Naguib Mechawar, Vahram Haroutunian, Jacques Epelbaum, Stéphanie Daumas, Salah El Mestikawy
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Abstract Synaptic loss, plaques and neurofibrillary tangles are viewed as hallmarks of Alzheimer’s disease (AD). This study investigated synaptic markers in neocortical Brodmann area 9 (BA9) samples from 171 subjects with and without AD at differen
Externí odkaz:
https://doaj.org/article/c7b90a287ba34fcc92a652b92c9be045
Autor:
Andrew T. McKenzie, Sarah Moyon, Minghui Wang, Igor Katsyv, Won-Min Song, Xianxiao Zhou, Eric B. Dammer, Duc M. Duong, Joshua Aaker, Yongzhong Zhao, Noam Beckmann, Pei Wang, Jun Zhu, James J. Lah, Nicholas T. Seyfried, Allan I. Levey, Pavel Katsel, Vahram Haroutunian, Eric E. Schadt, Brian Popko, Patrizia Casaccia, Bin Zhang
Publikováno v:
Molecular Neurodegeneration, Vol 12, Iss 1, Pp 1-20 (2017)
Abstract Background Oligodendrocytes (OLs) and myelin are critical for normal brain function and have been implicated in neurodegeneration. Several lines of evidence including neuroimaging and neuropathological data suggest that Alzheimer’s disease
Externí odkaz:
https://doaj.org/article/8d4fe7e565604e8b95a879118cca0dc9
Akademický článek
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Akademický článek
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K zobrazení výsledku je třeba se přihlásit.
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Autor:
Minghui Wang, Panos Roussos, Andrew McKenzie, Xianxiao Zhou, Yuji Kajiwara, Kristen J. Brennand, Gabriele C. De Luca, John F. Crary, Patrizia Casaccia, Joseph D. Buxbaum, Michelle Ehrlich, Sam Gandy, Alison Goate, Pavel Katsel, Eric Schadt, Vahram Haroutunian, Bin Zhang
Publikováno v:
Genome Medicine, Vol 8, Iss 1, Pp 1-21 (2016)
Abstract Background Alzheimer’s disease (AD) is the most common form of dementia, characterized by progressive cognitive impairment and neurodegeneration. However, despite extensive clinical and genomic studies, the molecular basis of AD developmen
Externí odkaz:
https://doaj.org/article/6f5c9ccb12a04ff398d143576bc62ad4
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0206547 (2018)
A large body of literature links risk of cognitive decline, mild cognitive impairment (MCI) and dementia with Type 2 Diabetes (T2D) or pre-diabetes. Accumulating evidence implicates a close relationship between the brain insulin receptor signaling pa
Externí odkaz:
https://doaj.org/article/fe9e5b4f32b94a84a41804ab6ef024da
Autor:
Zhao W, Wang J, Varghese M, Ho L, Mazzola P, Haroutunian V, Katsel PL, Gibson GE, Levine S, Dubner L, Pasinetti GM
Publikováno v:
Neuropsychiatric Disease and Treatment, Vol 2015, Iss default, Pp 565-574 (2015)
Wei Zhao,1,2 Jun Wang,1,2 Merina Varghese,1 Lap Ho,1,2 Paolo Mazzola,1,3 Vahram Haroutunian,2,4,5 Pavel L Katsel,2,4 Gary E Gibson,6 Samara Levine,1 Lauren Dubner,1 Giulio Maria Pasinetti1,2,4,7 1Department of Neurology, Icahn School of Medicine at M
Externí odkaz:
https://doaj.org/article/f88b5a94ee75469cadd571c9dc4ce859