Zobrazeno 1 - 10
of 2 200
pro vyhledávání: '"P, Gmeiner"'
Autor:
Lior Peri, Donna Matzov, Dominic R. Huxley, Alon Rainish, Fabrizio Fierro, Liel Sapir, Tara Pfeiffer, Lukas Waterloo, Harald Hübner, Yoav Peleg, Peter Gmeiner, Peter J. McCormick, Dorothee Weikert, Masha Y. Niv, Moran Shalev-Benami
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Bitter taste receptors (TAS2Rs), a subfamily of G-protein coupled receptors (GPCRs) expressed orally and extraorally, elicit signaling in response to a large set of tastants. Among 25 functional TAS2Rs encoded in the human genome, TAS2R14 is
Externí odkaz:
https://doaj.org/article/ffe236aefc0341b29447e20725da57e1
Autor:
Kim-Viktoria Bolik, Jan Hellmann, Simone Maschauer, Eduard Neu, Jürgen Einsiedel, Patrick Riss, Nora Vogg, Jörg König, Martin F. Fromm, Harald Hübner, Peter Gmeiner, Olaf Prante
Publikováno v:
EJNMMI Research, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Background The orexin receptor (OXR) plays a role in drug addiction and is aberrantly expressed in colorectal tumors. Subtype-selective OXR PET ligands suitable for in vivo use have not yet been reported. This work reports the development of
Externí odkaz:
https://doaj.org/article/7220bee43e0941a9b4e53a8f1aa38dba
AI-based design tools are proliferating in professional software to assist engineering and industrial designers in complex manufacturing and design tasks. These tools take on more agentic roles than traditional computer-aided design tools and are oft
Externí odkaz:
http://arxiv.org/abs/2303.00192
Generative, ML-driven interactive systems have the potential to change how people interact with computers in creative processes - turning tools into co-creators. However, it is still unclear how we might achieve effective human-AI collaboration in op
Externí odkaz:
http://arxiv.org/abs/2207.02996
Autor:
Jennifer M. Finan, Roberto Di Niro, Soon Young Park, Kang Jin Jeong, Madeline D. Hedberg, Alexander Smith, Grace A. McCarthy, Alex O. Haber, John Muschler, Rosalie C. Sears, Gordon B. Mills, William H. Gmeiner, Jonathan R. Brody
Publikováno v:
Cancer Biology & Therapy, Vol 25, Iss 1 (2024)
Pancreatic ductal adenocarcinoma (PDAC) is a lethal disease soon to become the second leading cause of cancer deaths in the US. Beside surgery, current therapies have narrow clinical benefits with systemic toxicities. FOLFIRINOX is the current standa
Externí odkaz:
https://doaj.org/article/31179cb813084425aaab19da48c81dcf
Publikováno v:
Frontiers in Earth Science, Vol 12 (2024)
Plastic pollution in aquatic environments is a growing concern, with rivers recognized as major pathways. However, rivers themselves are also subject to pollution. Hence, understanding riverine plastic transport dynamics is essential for mitigating e
Externí odkaz:
https://doaj.org/article/5682624aed44417ca07f23f2f9d3acf1
Autor:
Enzo Lüsebrink, MD, Hugo Lanz, MD, Leonhard Binzenhöfer, MD, Sabine Hoffmann, PhD, Julia Höpler, BSc, Marie Kraft, BSc, Nils Gade, MD, Jonas Gmeiner, MD, Daniel Roden, MD, Inas Saleh, MD, Christian Hagl, MD, Georg Nickenig, MD, Steffen Massberg, MD, Sebastian Zimmer, MD, Raúl Nicolás Jamin, MD, Clemens Scherer, MD
Publikováno v:
Critical Care Explorations, Vol 6, Iss 7, p e1117 (2024)
OBJECTIVES:. Cardiogenic shock (CS) is associated with high mortality. Patients treated for CS mostly require heparin therapy, which may be associated with complications such as heparin-induced thrombocytopenia (HIT). HIT represents a serious conditi
Externí odkaz:
https://doaj.org/article/bc81ccb0a40744e9a6546fd8cce02ca2
Autor:
Nico Stroh, Harald Stefanits, Alexander Maletzky, Sophie Kaltenleithner, Stefan Thumfart, Michael Giretzlehner, Richard Drexler, Franz L. Ricklefs, Lasse Dührsen, Stefan Aspalter, Philip Rauch, Andreas Gruber, Matthias Gmeiner
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Machine learning (ML) has revolutionized data processing in recent years. This study presents the results of the first prediction models based on a long-term monocentric data registry of patients with microsurgically treated unruptured intra
Externí odkaz:
https://doaj.org/article/d994ca0583cb4cf7b76fcab6b629caf6
Autor:
Nico Stroh-Holly, Philip Rauch, Harald Stefanits, Philipp Hermann, Helga Wagner, Michael Sonnberger, Maria Gollwitzer, Stefan Aspalter, Andreas Gruber, Matthias Gmeiner
Publikováno v:
Brain Sciences, Vol 14, Iss 11, p 1068 (2024)
Background/Objectives: Microsurgical clipping has traditionally been considered a standard treatment for middle cerebral artery (MCA) aneurysms. Recently, a caseload reduction related to improved endovascular treatment options has occurred in cerebro
Externí odkaz:
https://doaj.org/article/afcc957cc2eb4f66bc1394b7634ed7ad
Autor:
Jozsef Nagy, Wolfgang Fenz, Veronika M. Miron, Stefan Thumfart, Julia Maier, Zoltan Major, Harald Stefanits, Johannes Oberndorfer, Nico Stroh, Vanessa Mazanec, Philip-Rudolf Rauch, Andreas Gruber, Matthias Gmeiner
Publikováno v:
Brain Sciences, Vol 14, Iss 10, p 977 (2024)
Background: Hemodynamics during the growth process of cerebral aneurysms are incompletely understood. We developed a novel fluid–structure interaction analysis method for the identification of relevant scenarios of aneurysm onset. Method: This meth
Externí odkaz:
https://doaj.org/article/69b677a379034697ae118d77f6f6ba1c