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pro vyhledávání: '"P, Couillin"'
Akademický článek
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Autor:
Mégane Nascimento, Sarah Huot-Marchand, Manoussa Fanny, Marjolène Straube, Marc Le Bert, Florence Savigny, Lionel Apetoh, Jacques Van Snick, Fabrice Trovero, Mathias Chamaillard, Valérie F. J. Quesniaux, Bernhard Ryffel, Philippe Gosset, Aurélie Gombault, Nicolas Riteau, Harry Sokol, Isabelle Couillin
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Chronic obstructive pulmonary disease (COPD) is a major health issue primarily caused by cigarette smoke (CS) and characterized by breathlessness and repeated airway inflammation. NLRP6 is a cytosolic innate receptor controlling intestinal inflammati
Externí odkaz:
https://doaj.org/article/a7d159a73b8e40fbaeb58a9775e4aac6
Autor:
Sandra Carignon, Dorian De Moura Rodrigues, David Gosset, Elodie Culerier, Sarah Huot-Marchand, Florence Savigny, Eric Kaya, Valerie Quesniaux, Aurélie Gombault, Isabelle Couillin, Bernhard Ryffel, Marc Le Bert, Nicolas Riteau
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionThe pathogenesis of chronic lung diseases is multifaceted with a major role of recurrent micro-injuries of the epithelium. While several reports clearly indicated a prominent role for surfactant-producing alveolar epithelial type 2 (AT2)
Externí odkaz:
https://doaj.org/article/71754b8105ab4c509c24ac5dfc6cb235
Akademický článek
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Autor:
Flora Vasile, Elena Dossi, Julien Moulard, Pascal Ezan, Laure Lecoin, Martine Cohen-Salmon, Philippe Mailly, Marc Le Bert, Isabelle Couillin, Alexis Bemelmans, Nathalie Rouach
Publikováno v:
PLoS Biology, Vol 20, Iss 12, p e3001891 (2022)
Astroglial release of molecules is thought to actively modulate neuronal activity, but the nature, release pathway, and cellular targets of these neuroactive molecules are still unclear. Pannexin 1, expressed by neurons and astrocytes, form nonselect
Externí odkaz:
https://doaj.org/article/35b803277e2a4c5fae0e9554e11ca1f2
Autor:
Sarah Huot-Marchand, Mégane Nascimento, Elodie Culerier, Mélissa Bourenane, Florence Savigny, Corinne Panek, Cindy Serdjebi, Marc Le Bert, Valérie F. J. Quesniaux, Bernhard Ryffel, Petr Broz, Nicolas Riteau, Aurélie Gombault, Isabelle Couillin
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Chronic pulmonary inflammation and chronic obstructive pulmonary disease (COPD) are major health issues largely due to air pollution and cigarette smoke (CS) exposure. The role of the innate receptor NLRP3 (nucleotide-binding domain and leucine-rich
Externí odkaz:
https://doaj.org/article/6d26fc733ad047d9ac5a9f202429cc1e
Autor:
Alexandre H. Lopes, Rangel L. Silva, Miriam D. Fonseca, Francisco I. Gomes, Alexandre G. Maganin, Lucas S. Ribeiro, Lucas Maciel Mauriz Marques, Fernando Q. Cunha, Jose C. Alves-Filho, Dario S. Zamboni, Norberto P. Lopes, Bernardo S. Franklin, Aurélie Gombault, Fernando Silva Ramalho, Valerie F. J. Quesniaux, Isabelle Couillin, Bernhard Ryffel, Thiago M. Cunha
Publikováno v:
Cell Communication and Signaling, Vol 18, Iss 1, Pp 1-17 (2020)
Abstract Background Low molecular weight carrageenan (Cg) is a seaweed-derived sulfated polysaccharide widely used as inflammatory stimulus in preclinical studies. However, the molecular mechanisms of Cg-induced inflammation are not fully elucidated.
Externí odkaz:
https://doaj.org/article/fe56c29d443545788d694f1ed8880f87
Autor:
Isabelle Couillin, Nicolas Riteau
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Innate immunity is regulated by a broad set of evolutionary conserved receptors to finely probe the local environment and maintain host integrity. Besides pathogen recognition through conserved motifs, several of these receptors also sense aberrant o
Externí odkaz:
https://doaj.org/article/5ff4baa8334c4009a6c672c486e2b5d3
Publikováno v:
Cells, Vol 11, Iss 21, p 3483 (2022)
The cGAS–STING pathway displays important functions in the regulation of innate and adaptive immunity following the detection of microbial and host-derived DNA. Here, we briefly summarize biological functions of STING and review recent literature h
Externí odkaz:
https://doaj.org/article/c375d078fcd7431a9e9616c8784f1332
Akademický článek
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