Randomised multicentre effectiveness trial of rapid syndromic testing by panel assay in children presenting to European emergency departments with acute respiratory infections—trial protocol for the ADEQUATE Paediatric trial

Autor: Alexander Ross, Andrew Atkinson, Maarten J Postma, Federica Vanoni, Julia A Bielicki, Fernando Antoñanzas, Herman Goossens, Elias Iosifidis, Emmanuel Roilides, Mark Lyttle, Elia Vitale, Malte Kohns Vasconcelos, Florence Allantaz, Claire Hawksworth, Pablo Rojo, Dalia Dawoud, Surbhi Malhotra-Kumar, Silke Peter, Hanna Renk, Marc Bonten, Manuel Gijon, Maggie Nyirenda Nyang’wa, Thea van Asselt, Anthony Hemeson, Cristina Prat Aymerich, Simon van der Pol, Parthena Savvidou, Sophie Vandepitte, Emma Gardiner, Michelle Clements, Yasmine Yau, Giulio Vecchia, Federica D’Ambrosio, Wietske Bouwman, Marjolein van Esschoten, Frank Leus, David de Pooter, Leen Timbermont, Juan Pablo Rodriguez Ruiz, Benjamin Hommel, Marie Tessonneau, Jean-Louis Tissier, Philippe Cleuziat, Pim van Dorst, Paula Rojas, Marino Gonzales, Harry Heijerman, Henri van Werkhoven, Maria Simitsopoulou, Kalliopi Pantzartzi, Kostas Zarras, Argyro Ftergioti, Maria Kitsou, Aristea Karypiadou, Charis Lampada, Konstantina Charisi, Olga Tsiatsiou, Elsa Chorafa, Elisavet Michailidou, Ann-Kathrin Stiegler, Carmen Junk, Kristina Kiesel, Maren Belschner, Maike Seyfried, Kristina Schmauder, Tobias Walter, Dominic Imort, Fabian Behret, Rahel Berger, Leon Pfeiffer, Emanuela Früh, Elena Robinson, Andrea Marten, Claudia Werner, Rosa Calderón, Fátima Machín, Laura Cabello, Andrea Seoane, Sofía Mesa, Lidia Oviedo, Luisa Barón, Irene Hernández, Lisa Capozzi, Louisa Brock, Cecilia Hultin, Louise F Hill, Alessia Severi Conti, Gianluca Gualco

Publikováno v: BMJ Open, Vol 14, Iss 4 (2024)

Introduction Syndromic panel assays, that is, using one test to simultaneously target multiple pathogens with overlapping signs and symptoms, have been integrated into routine paediatric care over the past decade, mainly for more severely ill and hos

Externí odkaz: https://doaj.org/article/d5c0be897b4147ba974e10f2eee0d1ef

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Molecular characterization of pcp, the structural gene encoding the pyrrolidone carboxylyl peptidase from Streptococcus pyogenes

Autor: Jk. Robert-Baudouy, A.C. Awadé, P. Cleuziat

Publikováno v: Molecular Microbiology. 6:2051-2063

Summary This paper describes the cloning of a gene (pep) coding for pyrrolidone carboxylyl peptidase (PYRase), an enzyme which selectively removes N-terminal pyroglutamic acid residues from polypeptldes. This gene was isolated from Streptococcus pyog

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ae8c3d60123489db0759d3dbf20f6ab
https://doi.org/10.1111/j.1365-2958.1992.tb01378.x