Zobrazeno 1 - 10
of 164
pro vyhledávání: '"P, Buckhaults"'
Autor:
Qi Zhang, Alexander A. Chumanevich, Ivy Nguyen, Anastasiya A. Chumanevich, Nora Sartawi, Jake Hogan, Minou Khazan, Quinn Harris, Bryson Massey, Ioulia Chatzistamou, Phillip J. Buckhaults, Carolyn E. Banister, Michael Wirth, James R. Hebert, E. Angela Murphy, Lorne J. Hofseth
Publikováno v:
Toxicology Reports, Vol 11, Iss , Pp 221-232 (2023)
The incidence of colorectal cancer (CRC) among young people has been on the rise for the past four decades and its underlying causes are only just starting to be uncovered. Recent studies suggest that consuming ultra-processed foods and pro-inflammat
Externí odkaz:
https://doaj.org/article/c46b816ca39b43b3a837b003e35ee318
Autor:
Monish Ram Makena, Myungjun Ko, Allatah X. Mekile, Nanami Senoo, Donna K. Dang, John Warrington, Phillip Buckhaults, C. Conover Talbot, Jr., Steven M. Claypool, Rajini Rao
Publikováno v:
Redox Biology, Vol 50, Iss , Pp 102240- (2022)
A complex interplay between the extracellular space, cytoplasm and individual organelles modulates Ca2+ signaling to impact all aspects of cell fate and function. In recent years, the molecular machinery linking endoplasmic reticulum stores to plasma
Externí odkaz:
https://doaj.org/article/0b300ccbdec4497a989595ebae280235
Autor:
Ozge Saatci, Aysegul Kaymak, Umar Raza, Pelin G. Ersan, Ozge Akbulut, Carolyn E. Banister, Vitali Sikirzhytski, Unal Metin Tokat, Gamze Aykut, Suhail A. Ansari, Hayriye Tatli Dogan, Mehmet Dogan, Pouria Jandaghi, Aynur Isik, Fatma Gundogdu, Kemal Kosemehmetoglu, Omer Dizdar, Sercan Aksoy, Aytekin Akyol, Aysegul Uner, Phillip J. Buckhaults, Yasser Riazalhosseini, Ozgur Sahin
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
The development of chemoresistance is a major hurdle in triple negative breast cancer (TNBC). Here, the authors show that lysyl oxidase (LOX) is overexpressed in chemoresistant TNBCs, and when inhibited reduces collagen cross-linking, fibronectin fib
Externí odkaz:
https://doaj.org/article/f292a5a9fd8f4954a8c5c7cfe015c25d
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Clinical studies have reported an increased risk of depression and anxiety disorders among individuals who are obese, and women are more likely than men to suffer from depression, anxiety, and obesity. However, the effects of obesity-promoting diets
Externí odkaz:
https://doaj.org/article/0cfeb2a96bfe40e5830dd952a9b88532
Akademický článek
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Autor:
Mohammed L. Ibrahim, John D. Klement, Chunwan Lu, Priscilla S. Redd, Wei Xiao, Dafeng Yang, Darren D. Browning, Natasha M. Savage, Phillip J. Buckhaults, Herbert C. Morse, III, Kebin Liu
Publikováno v:
Cell Reports, Vol 25, Iss 11, Pp 3036-3046.e6 (2018)
Summary: IL-10 functions as a suppressor of colitis and colitis-associated colon cancer, but it is also a risk locus associated with ulcerative colitis. The mechanism underlying the contrasting roles of IL-10 in inflammation and colon cancer is unkno
Externí odkaz:
https://doaj.org/article/733e420bc469472f90edb17dee48142b
Akademický článek
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Akademický článek
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K zobrazení výsledku je třeba se přihlásit.
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Autor:
Paul F. Meeh, Christopher L. Farrell, Randal Croshaw, Hampton Crimm, Samantha K. Miller, Dora Oroian, Sangeeta Kowli, Jinyu Zhu, Wayne Carver, Wensong Wu, Edsel Pena, Phillip J. Buckhaults
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 11, Iss 10, Pp 1074-1083 (2009)
We used digital long serial analysis of gene expression to discover gene expression differences between node-negative and node-positive colorectal tumors and developed a multigene classifier able to discriminate between these two tumor types. We prep
Externí odkaz:
https://doaj.org/article/5ab48358639d4b3981939f043661bb26
Autor:
Ying Lin, Phillip J. Buckhaults, Jeffrey R. Lee, Hairong Xiong, Christopher Farrell, Robert H. Podolsky, Robert R. Schade, William S. Dynan
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 11, Iss 9, Pp 864-873 (2009)
Metastatic dissemination of primary tumors is responsible for 90% of colorectal cancer (CRC) deaths. The presence of positive lymph nodes, which separates stage I/II from stage III CRC, is a particularly key factor in patient management. Here, we des
Externí odkaz:
https://doaj.org/article/f9a8e2878335404b96cff21e0852e460