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Akademický článek

Meldonium-induced steatosis is associated with increased delta 6 desaturation and reduced elongation of n-6 polyunsaturated fatty acids

Autor: Bodil Bjørndal, Siri Lunde Tungland, Pavol Bohov, Magne O. Sydnes, Simon N. Dankel, Lise Madsen, Rolf K Berge

Publikováno v: Liver Research, Vol 8, Iss 3, Pp 152-164 (2024)

Background and objective: Metabolic associated fatty liver disease (MAFLD) is associated with abnormal lipid metabolism. Mitochondrial dysfunction is considered an important factor in the onset of MAFLD, whereas altered fatty acid composition has bee

Externí odkaz: https://doaj.org/article/f184559c38b14a08a85a87ff27b29649

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Akademický článek

Sex-specific responses in glucose-insulin homeostasis and lipoprotein-lipid components after high-dose supplementation with marine n-3 PUFAs in abdominal obesity: a randomized double-blind crossover study

Autor: Johnny Laupsa-Borge, Elise Grytten, Pavol Bohov, Bodil Bjørndal, Elin Strand, Jon Skorve, Jan Erik Nordrehaug, Rolf K. Berge, Espen Rostrup, Gunnar Mellgren, Simon N. Dankel, Ottar K. Nygård

Publikováno v: Frontiers in Nutrition, Vol 10 (2023)

BackgroundClinical studies on effects of marine-derived omega-3 (n-3) polyunsaturated fatty acids (PUFAs), mainly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), and the plant-derived omega-6 (n-6) PUFA linoleic acid (LA) on lipoprotein-l

Externí odkaz: https://doaj.org/article/9eef044a1e134b3fa63371c082216ec8

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Akademický článek

Low fibre intake is associated with gut microbiota alterations in chronic heart failure

Autor: Cristiane C.K. Mayerhofer, Martin Kummen, Kristian Holm, Kaspar Broch, Ayodeji Awoyemi, Beate Vestad, Christopher Storm‐Larsen, Ingebjørg Seljeflot, Thor Ueland, Pavol Bohov, Rolf K. Berge, Asbjørn Svardal, Lars Gullestad, Arne Yndestad, Pål Aukrust, Johannes R. Hov, Marius Trøseid

Publikováno v: ESC Heart Failure, Vol 7, Iss 2, Pp 456-466 (2020)

Abstract Aims Recent reports have suggested that patients with heart failure (HF) have an altered gut microbiota composition; however, associations with diet remain largely uninvestigated. We aimed to explore differences in the gut microbiota between

Externí odkaz: https://doaj.org/article/0d22c831ff574565a13001dff04bb58e

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Akademický článek

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Akademický článek

Short-Term Activation of Peroxisome Proliferator-Activated Receptors α and γ Induces Tissue-Specific Effects on Lipid Metabolism and Fatty Acid Composition in Male Wistar Rats

Autor: Elin Strand, Vegard Lysne, Mari Lausund Grinna, Pavol Bohov, Asbjørn Svardal, Ottar Nygård, Rolf K. Berge, Bodil Bjørndal

Publikováno v: PPAR Research, Vol 2019 (2019)

Dietary fatty acids (FAs) affect certain metabolic routes, including pathways controlled by the peroxisome proliferator-activated receptors (PPARs), but tissue-specific effects are not well-defined. Thus, the aim was to compare the metabolic response

Externí odkaz: https://doaj.org/article/05f01ef0fe7c4c6ebd3024c1d1e9b67b

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Akademický článek

A Phospholipid-Protein Complex from Krill with Antioxidative and Immunomodulating Properties Reduced Plasma Triacylglycerol and Hepatic Lipogenesis in Rats

Autor: Marie S. Ramsvik, Bodil Bjørndal, Inge Bruheim, Pavol Bohov, Rolf K. Berge

Publikováno v: Marine Drugs, Vol 13, Iss 7, Pp 4375-4397 (2015)

Dietary intake of marine omega-3 polyunsaturated fatty acids (n-3 PUFAs) can change the plasma profile from atherogenic to cardioprotective. In addition, there is growing evidence that proteins of marine origin may have health benefits. We investigat

Externí odkaz: https://doaj.org/article/77a3996185da4e42b1fa63e9d5c9ccd9

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Akademický článek

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Akademický článek

Circulating B-vitamins and smoking habits are associated with serum polyunsaturated Fatty acids in patients with suspected coronary heart disease: a cross-sectional study.

Autor: Eli Skeie, Elin Strand, Eva R Pedersen, Bodil Bjørndal, Pavol Bohov, Rolf K Berge, Gard F T Svingen, Reinhard Seifert, Per M Ueland, Øivind Midttun, Arve Ulvik, Steinar Hustad, Christian A Drevon, Jesse F Gregory, Ottar Nygård

Publikováno v: PLoS ONE, Vol 10, Iss 6, p e0129049 (2015)

The long-chain polyunsaturated fatty acids are considered to be of major health importance, and recent studies indicate that their endogenous metabolism is influenced by B-vitamin status and smoking habits. We investigated the associations of circula

Externí odkaz: https://doaj.org/article/f46b58114f89485493be8a81ad3e4fcc

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Akademický článek

Impact of mitochondrial β-oxidation in fatty acid-mediated inhibition of glioma cell proliferation

Autor: Kjetil Berge, Karl Johan Tronstad, Pavol Bohov, Lise Madsen, Rolf K. Berge

Publikováno v: Journal of Lipid Research, Vol 44, Iss 1, Pp 118-127 (2003)

Tetradecylthioacetic acid (T11111141), which cannot be β-oxidized, exerts growth-limiting properties in glioma cells. In order to investigate the importance of modulated lipid metabolism and alterations in mitochondrial properties in this cell death

Externí odkaz: https://doaj.org/article/e8dd692e2d1f43cabd1b1c9d49c1b412

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