DNA Methylation signatures underpinning blood neutrophil to lymphocyte ratio during first week of human life

Autor: David Martino, Nina Kresoje, Nelly Amenyogbe, Rym Ben-Othman, Bing Cai, Mandy Lo, Olubukola Idoko, Oludare A. Odumade, Reza Falsafi, Travis M. Blimkie, Andy An, Casey P. Shannon, Sebastiano Montante, Bhavjinder K. Dhillon, Joann Diray-Arce, Al Ozonoff, Kinga K. Smolen, Ryan R. Brinkman, Kerry McEnaney, Asimenia Angelidou, Peter Richmond, Scott J. Tebbutt, the EPIC-HIPC consortium, Beate Kampmann, Ofer Levy, Robert E. W. Hancock, Amy H. Y. Lee, Tobias R. Kollmann

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)

Abstract Understanding of newborn immune ontogeny in the first week of life will enable age-appropriate strategies for safeguarding vulnerable newborns against infectious diseases. Here we conducted an observational study exploring the immunological

Externí odkaz: https://doaj.org/article/f8167ccffdeb4b0d9144c24cdeaf6fcb

Plasma adenosine deaminase-1 and -2 activities are lower at birth in Papua New Guinea than in The Gambia but converge over the first weeks of life

Autor: Thomas S. Kouyate, Athena N. Nguyen, Alec L. Plotkin, Rebeca Ford, Olubukola T. Idoko, Oludare A. Odumade, Geraldine Masiria, Joe Jude, Joann Diray-Arce, Kerry McEnaney, Al Ozonoff, Hanno Steen, Tobias R. Kollmann, Peter C. Richmond, Anita H. J. van den Biggelaar, Beate Kampmann, William Pomat, Ofer Levy, Kinga K. Smolen

Publikováno v: Frontiers in Immunology, Vol 15 (2024)

IntroductionDynamic cellular and molecular adaptations in early life significantly impact health and disease. Upon birth, newborns are immediately challenged by their environment, placing urgent demands on the infant immune system. Adenosine deaminas

Externí odkaz: https://doaj.org/article/3469119b920e45cb8cafff5b9af4ea6b

Association of maternal fish consumption and ω-3 supplement use during pregnancy with child autism-related outcomes: results from a cohort consortium analysis

Autor: Smith, PB, Newby, KL, Jacobson, LP, Catellier, DJ, Gershon, R, Cella, D, Alshawabkeh, AN, Cordero, J, Meeker, J, Aschner, J, Teitelbaum, SL, Stroustrup, A, Mansbach, JM, Spergel, JM, Samuels-Kalow, ME, Stevenson, MD, Bauer, CS, Koinis Mitchell, D, Deoni, S, D’Sa, V, Duarte, CS, Monk, C, Posner, J, Canino, G, Seroogy, C, Bendixsen, C, Hertz-Picciotto, I, Keenan, K, Karr, C, Tylavsky, F, Mason, A, Zhao, Q, Sathyanarayana, S, LeWinn, KZ, Lester, B, Carter, B, Pastyrnak, S, Neal, C, Smith, L, Helderman, J, Weiss, ST, Litonjua, A, O’Connor, G, Zeiger, R, Bacharier, L, Volk, H, Ozonoff, S, Schmidt, R, Simhan, H, Kerver, JM, Barone, C, Fussman, C, Paneth, N, Elliott, M, Ruden, D, Porucznik, C, Giardino, A, Innocenti, M, Silver, R, Conradt, E, Bosquet-Enlow, M, Huddleston, K, Nguyen, R, Trasande, L, Swan, S, Lyall, Kristen, Westlake, Matt, Musci, Rashelle J, Gachigi, Kennedy, Barrett, Emily S, Bastain, Theresa M, Bush, Nicole R, Buss, Claudia, Camargo, Carlos A, Jr., Croen, Lisa A, Dabelea, Dana, Dunlop, Anne L, Elliott, Amy J, Ferrara, Assiamira, Ghassabian, Akhgar, Gern, James E, Hare, Marion E, Hertz-Picciotto, Irva, Hipwell, Alison E, Hockett, Christine W, Karagas, Margaret R, Lugo-Candelas, Claudia, O’Connor, Thomas G, Schmidt, Rebecca J, Stanford, Joseph B, Straughen, Jennifer K, Shuster, Coral L, Wright, Robert O, Wright, Rosalind J, Zhao, Qi, Oken, Emily

Publikováno v: In The American Journal of Clinical Nutrition September 2024 120(3):583-592

Features of acute COVID-19 associated with post-acute sequelae of SARS-CoV-2 phenotypes: results from the IMPACC study

Autor: Al Ozonoff, Naresh Doni Jayavelu, Shanshan Liu, Esther Melamed, Carly E. Milliren, Jingjing Qi, Linda N. Geng, Grace A. McComsey, Charles B. Cairns, Lindsey R. Baden, Joanna Schaenman, Albert C. Shaw, Hady Samaha, Vicki Seyfert-Margolis, Florian Krammer, Lindsey B. Rosen, Hanno Steen, Caitlin Syphurs, Ravi Dandekar, Casey P. Shannon, Rafick P. Sekaly, Lauren I. R. Ehrlich, David B. Corry, Farrah Kheradmand, Mark A. Atkinson, Scott C. Brakenridge, Nelson I. Agudelo Higuita, Jordan P. Metcalf, Catherine L. Hough, William B. Messer, Bali Pulendran, Kari C. Nadeau, Mark M. Davis, Ana Fernandez Sesma, Viviana Simon, Harm van Bakel, Seunghee Kim-Schulze, David A. Hafler, Ofer Levy, Monica Kraft, Chris Bime, Elias K. Haddad, Carolyn S. Calfee, David J. Erle, Charles R. Langelier, Walter Eckalbar, Steven E. Bosinger, IMPACC Network, Bjoern Peters, Steven H. Kleinstein, Elaine F. Reed, Alison D. Augustine, Joann Diray-Arce, Holden T. Maecker, Matthew C. Altman, Ruth R. Montgomery, Patrice M. Becker, Nadine Rouphael

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)

Abstract Post-acute sequelae of SARS-CoV-2 (PASC) is a significant public health concern. We describe Patient Reported Outcomes (PROs) on 590 participants prospectively assessed from hospital admission for COVID-19 through one year after discharge. M

Externí odkaz: https://doaj.org/article/ec0ddc29cd90460ca1ec27bea2b831b8

Birth outcomes in relation to neighborhood food access and individual food insecurity during pregnancy in the Environmental Influences on Child Health Outcomes (ECHO)-wide cohort study

Autor: Smith, P.B., Newby, L.K., Jacobson, L.P., Catellier, D.J., Fuselier, G, Gershon, R, Cella, D, Teitelbaum, S.L., Stroustrup, A, Merhar, S, Lampland, A, Reynolds, A, Hudak, M, Pryhuber, G, Moore, P, Washburn, L, Gatzke-Kopp, L, Swingler, M, Laham, F.R., Mansbach, J.M., Wu, S, Spergel, J.M., Celedón, J.C., Puls, H.T., Teach, S.J., Porter, S.C., Waynik, I.Y., Iyer, S.S., Samuels-Kalow, M.E., Thompson, A.D., Stevenson, M.D., Bauer, C.S., Inhofe, N.R., Boos, M, Macias, C.G., Koinis Mitchell, D, Duarte, C.S., Monk, C, Posner, J, Canino, G, Croen, L, Gern, J, Zoratti, E, Seroogy, C, Bendixsen, C, Jackson, D, Bacharier, L, O’Connor, G, Kattan, M, Wood, R, Rivera-Spoljaric, K, Hershey, G, Johnson, C, Bastain, T, Farzan, S, Habre, R, Hertz-Picciotto, I, Hipwell, A, Keenan, K, Karr, C, Tylavsky, F, Mason, A, Zhao, Q, Sathyanarayana, S, Bush, N, LeWinn, K.Z., Carter, B, Pastyrnak, S, Neal, C, Smith, L, Helderman, J, Leve, L, Neiderhiser, J, Weiss, S.T., Litonjua, A, Zeiger, R, McEvoy, C, Tepper, R, Lyall, K, Volk, H, Landa, R, Ozonoff, S, Schmidt, R, Dager, S, Schultz, R, Piven, J, O’Shea, M, Vaidya, R, Obeid, R, Rollins, C, Bear, K, Lenski, M, Singh, R, Msall, M, Frazier, J, Gogcu, S, Montgomery, A, Kuban, K, Douglass, L, Jara, H, Joseph, R, Kerver, J.M., Barone, C, Fussman, C, Paneth, N, Elliott, M, Ruden, D, Herbstman, J, Schantz, S, Woodruff, T, Stanford, J, Porucznik, C, Giardino, A, Wright, R.J., Bosquet-Enlow, M, Huddleston, K, Nguyen, R, Barrett, E, Swan, S, Miller, R, Aris, Izzuddin M, Lin, Pi-I D, Wu, Allison J, Dabelea, Dana, Lester, Barry M, Wright, Rosalind J, Karagas, Margaret R, Kerver, Jean M, Dunlop, Anne L, Joseph, Christine LM, Camargo, Carlos A, Jr., Ganiban, Jody M, Schmidt, Rebecca J, Strakovsky, Rita S, McEvoy, Cindy T, Hipwell, Alison E, O’Shea, Thomas Michael, McCormack, Lacey A, Maldonado, Luis E, Niu, Zhongzheng, Ferrara, Assiamira, Zhu, Yeyi, Chehab, Rana F, Kinsey, Eliza W, Bush, Nicole R, Nguyen, Ruby HN., Carroll, Kecia N, Barrett, Emily S, Lyall, Kristen, Sims-Taylor, Lauren M, Trasande, Leonardo, Biagini, Jocelyn M, Breton, Carrie V, Patti, Marisa A, Coull, Brent, Amutah-Onukagha, Ndidiamaka, Hacker, Michele R, James-Todd, Tamarra, Oken, Emily

Publikováno v: In The American Journal of Clinical Nutrition May 2024 119(5):1216-1226