Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Ozlem Kucukoglu"'
Autor:
Ali Canbay, Oliver Götze, Ozlem Kucukoglu, Sönke Weinert, Roland S. Croner, Theodor Baars, Mustafa K. Özçürümez, Robert K. Gieseler
Publikováno v:
Pharmaceutics, Vol 16, Iss 4, p 506 (2024)
l-Ornithine- l-aspartate (LOLA) reduces toxic ammonium (NH3) plasma levels in hepatic encephalopathy. NH3 detoxification/excretion is achieved by its incorporation into urea and glutamine via activation of carbamoyl phosphate synthetase 1 (CSP1) by l
Externí odkaz:
https://doaj.org/article/0427b3041a67404485ab812eaa259a96
Autor:
G. Seyda Seydel, Ozlem Kucukoglu, Akif Altinbas, O. Oguz Demir, Sezai Yilmaz, Hikmet Akkiz, Emrah Otan, Jan-Peter Sowa, Ali Canbay
Publikováno v:
Annals of Hepatology, Vol 15, Iss 5, Pp 662-672 (2016)
Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer and the third leading cause of cancer related death worldwide. In recent years, the prevalence of HCC has increased in both developing and developed countries. Most HCC ca
Externí odkaz:
https://doaj.org/article/945affc420214a7f93f60d4706193f40
Autor:
Mariia Lunova, Eugen Zizer, Ozlem Kucukoglu, Carolin Schwarz, Wolfgang H Dillmann, Martin Wagner, Pavel Strnad
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e39972 (2012)
BACKGROUND AND AIMS: Heat shock protein (Hsp) 72 is a molecular chaperone which is upregulated in response to a variety of stress situations and has a general cytoprotective function. Increased Hsp72 levels were implicated in protection from acute pa
Externí odkaz:
https://doaj.org/article/2647373778b84624916972459b9c6774
Autor:
Pavel Strnad, Ozlem Kucukoglu, Mariia Lunova, Nurdan Guldiken, Tim C Lienau, Felix Stickel, M Bishr Omary
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e32669 (2012)
Keratins 8 and 18 (K8/K18) are intermediate filament proteins that protect the liver from various forms of injury. Exonic K8/K18 variants associate with adverse outcome in acute liver failure and with liver fibrosis progression in patients with chron
Externí odkaz:
https://doaj.org/article/37908ec34fbd42778cc681e3f3ca15e1
Autor:
Pavel Strnad, Peggy Schwarz, Maria C D Rasenack, Ozlem Kucukoglu, Rayan I Habib, Dominik Heuberger, Robert Ehehalt, Michael W Müller, Adolf Stiehl, Guido Adler, Hasan Kulaksiz
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e16454 (2011)
BACKGROUND/AIMS: Hepcidin (gene name HAMP), an IL-6-inducible acute phase peptide with antimicrobial properties, is the key negative regulator of iron metabolism. Liver is the primary source of HAMP synthesis, but it is also produced by other tissues
Externí odkaz:
https://doaj.org/article/595a7362fdf64786abdff3decd289d3d
Autor:
Ozlem, Kucukoglu, Nurdan, Guldiken, Yu, Chen, Valentyn, Usachov, Amin, El-Heliebi, Johannes, Haybaeck, Helmut, Denk, Christian, Trautwein, Pavel, Strnad
Publikováno v:
Hepatology (Baltimore, Md.). 60(1)
Mallory-Denk bodies (MDBs) are protein aggregates consisting of ubiquitinated keratins 8/18 (K8/K18). MDBs are characteristic of alcoholic and nonalcoholic steatohepatitis (NASH) and discriminate between the relatively benign simple steatosis and the
Autor:
Guillermo Mazzolini, Jan-Peter Sowa, Catalina Atorrasagasti, Özlem Kücükoglu, Wing-Kin Syn, Ali Canbay
Publikováno v:
Cells, Vol 9, Iss 11, p 2458 (2020)
Non-alcoholic fatty liver disease (NAFLD) is defined clinicopathologically by the accumulation of lipids in >5% of hepatocytes and the exclusion of secondary causes of fat accumulation. NAFLD encompasses a wide spectrum of liver damage, extending fro
Externí odkaz:
https://doaj.org/article/c4ee70a15f7944a4a68e576c8ef2237e