Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Ozlem Bozdagi-Gunal"'
Autor:
Véronik Lachance, Qian Wang, Eric Sweet, Insup Choi, Cui-Zan Cai, Xu-Xu Zhuang, Yuanxi Zhang, Jessica Li Jiang, Robert D. Blitzer, Ozlem Bozdagi-Gunal, Bin Zhang, Jia-Hong Lu, Zhenyu Yue
Publikováno v:
Molecular Neurodegeneration, Vol 14, Iss 1, Pp 1-13 (2019)
Abstract Background Dysfunctional autophagy is implicated in Alzheimer’s Disease (AD) pathogenesis. The alterations in the expression of many autophagy related genes (ATGs) have been reported in AD brains; however, the disparity of the changes conf
Externí odkaz:
https://doaj.org/article/08130cf12c0d4ff3966594d207ddd573
Autor:
Abhishek Sahasrabudhe, Fatema Begum, Christopher A. Guevara, Chenel Morrison, Kuangfu Hsiao, Nebojsa Kezunovic, Ozlem Bozdagi-Gunal, Deanna L. Benson
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 12 (2021)
In humans, copy number variations in CYFIP1 appear to have sweeping physiological and structural consequences in the brain, either producing or altering the severity of intellectual disability, autism, and schizophrenia. Independently, SynGAP1 haploi
Externí odkaz:
https://doaj.org/article/52856214e3974abc914af233826f7ebd
Autor:
Hala Harony-Nicolas, Maya Kay, Johann du Hoffmann, Matthew E Klein, Ozlem Bozdagi-Gunal, Mohammed Riad, Nikolaos P Daskalakis, Sankalp Sonar, Pablo E Castillo, Patrick R Hof, Matthew L Shapiro, Mark G Baxter, Shlomo Wagner, Joseph D Buxbaum
Publikováno v:
eLife, Vol 6 (2017)
Mutations in the synaptic gene SHANK3 lead to a neurodevelopmental disorder known as Phelan-McDermid syndrome (PMS). PMS is a relatively common monogenic and highly penetrant cause of autism spectrum disorder (ASD) and intellectual disability (ID), a
Externí odkaz:
https://doaj.org/article/15f3de3779bb415499c0098f7ef83e2d
Autor:
Ekta Kumari, Fernando J. Velloso, Anna Wadhwa, Ioana Carcea, Ozlem Bozdagi Gunal, Steven W. Levison
Epidemiologic studies have demonstrated that infections during pregnancy increase the risk of offspring developing Schizophrenia, Autism, Depression and Bipolar Disorder and have implicated interleukin-6 (IL-6) as a causal agent. However, other cytok
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a0d86120ff42c0df6d47d316cb80a8f
https://doi.org/10.1101/2021.08.18.456694
https://doi.org/10.1101/2021.08.18.456694
Autor:
Luipa Khandker, Marisa A. Jeffries, Yun-Juan Chang, Marie L. Mather, Angelina V. Evangelou, Jennifer N. Bourne, Azadeh K. Tafreshi, Isis M. Ornelas, Ozlem Bozdagi-Gunal, Wendy B. Macklin, Teresa L. Wood
Publikováno v:
Cell reports. 38(9)
Brain and spinal cord oligodendroglia have distinct functional characteristics, and cell-autonomous loss of individual genes can result in different regional phenotypes. However, a molecular basis for these distinctions is unknown. Using single-cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8139f3d7726c99878a99393befcea65
https://pubmed.ncbi.nlm.nih.gov/35235799
https://pubmed.ncbi.nlm.nih.gov/35235799
Autor:
Marisa A. Jeffries, Jennifer N. Bourne, Teresa L. Wood, Isis M. Ornelas, Luipa Khandker, Yun-Juan Chang, Ozlem Bozdagi-Gunal, Marie L. Mather, Azadeh Kamali Tafreshi, Wendy B. Macklin
Publikováno v:
SSRN Electronic Journal.
Brain and spinal cord oligodendroglia have distinct functional characteristics, and cell autonomous loss of individual genes can result in different regional phenotypes. However, a molecular basis for these distinctions has not been identified. Using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e73dffb2cad504933b6f48016078733
https://doi.org/10.2139/ssrn.3817000
https://doi.org/10.2139/ssrn.3817000
Autor:
Luipa Khandker, Marisa A. Jeffries, Yun-Juan Chang, Marie L. Mather, Jennifer N. Bourne, Azadeh K. Tafreshi, Isis M. Ornelas, Ozlem Bozdagi-Gunal, Wendy B. Macklin, Teresa L. Wood
Brain and spinal cord oligodendroglia have distinct functional characteristics, and cell autonomous loss of individual genes can result in different regional phenotypes. However, sequencing studies to date have not revealed distinctions between brain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6aed9c0148de5b5829d4734c658a54d
https://doi.org/10.1101/2020.10.22.349209
https://doi.org/10.1101/2020.10.22.349209
Publikováno v:
The Journal of Neuroscience. 36:1564-1576
Copy number variations encompassing the gene encoding Cyfip1 have been associated with a variety of human diseases, including autism and schizophrenia. Here we show that juvenile mice hemizygous forCyfip1have altered presynaptic function, enhanced pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cf7af0668db05a0f34930963f6e3fe2
https://doi.org/10.1523/jneurosci.0511-15.2016
https://doi.org/10.1523/jneurosci.0511-15.2016
Autor:
Umut Agyuz, Ceyda Hayretdag, Ender Coskunpinar, Halime Yildirim, Pinar Algedik, Cumhur Gokhan Ekmekci, Ozlem Bozdagi Gunal
Publikováno v:
Gene Reports. 19:100618
Twin studies provide strong evidence that genetic factors have a major role in the etiology of autism spectrum disorder (ASD) but in most patients the underlying genetic cause of the disease is unknown. Here we used whole-exome sequencing to study ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7892f8c212c1b0de20dd0942c8bb0873
https://doi.org/10.1016/j.genrep.2020.100618
https://doi.org/10.1016/j.genrep.2020.100618
Autor:
Maya Kay, Johann du Hoffmann, Sankalp Sonar, Mohammed Riad, Patrick R. Hof, Nikolaos P. Daskalakis, Matthew E. Klein, Matthew L. Shapiro, Mark G. Baxter, Pablo E. Castillo, Hala Harony-Nicolas, Joseph D. Buxbaum, Ozlem Bozdagi-Gunal, Shlomo Wagner
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d35e332bd057bd6c1d08d7a7356eb5f
https://doi.org/10.7554/elife.18904.017
https://doi.org/10.7554/elife.18904.017