Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Ozden Yalcin-Ozuysal"'
Autor:
Seren Kecili, Esra Yilmaz, Ozge Solmaz Ozcelik, Muge Anil-Inevi, Zehra Elif Gunyuz, Ozden Yalcin-Ozuysal, Engin Ozcivici, H. Cumhur Tekin
Publikováno v:
Biosensors and Bioelectronics: X, Vol 15, Iss , Pp 100392- (2023)
Circulating tumor cells (CTCs) are crucial indicators of cancer metastasis. However, their rarity in the bloodstream and the heterogeneity of their surface biomarkers present challenges for their isolation. Here, we developed a hybrid microfluidic pl
Externí odkaz:
https://doaj.org/article/57813537d3d041b5becf3f4100ac26fb
Autor:
Muge Anil-Inevi, Sena Yaman, Ahu Arslan Yildiz, Gulistan Mese, Ozden Yalcin-Ozuysal, H. Cumhur Tekin, Engin Ozcivici
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Abstract Magnetic levitation though negative magnetophoresis is a novel technology to simulate weightlessness and has recently found applications in material and biological sciences. Yet little is known about the ability of the magnetic levitation sy
Externí odkaz:
https://doaj.org/article/d6d5a2a570c942d7b88bd9e6f2c86200
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132757 (2015)
IRF6, a member of Interferon Regulatory Factors (IRF) family, is involved in orofacial and epidermal development. In breast cancer cell lines ectopic expression of IRF6 reduces cell numbers suggesting a role as negative regulator of cell cycle. IRF6
Externí odkaz:
https://doaj.org/article/e75d9a1fdf634895bdf76e4117776769
Autor:
Kubra Telli, Ozden Yalcin-Ozuysal
Publikováno v:
Turkish Journal of Biochemistry. 48:88-95
Objectives Notch is a conserved pathway involved in cell-fate determination and homeostasis. Its dysregulation plays a role in poor prognosis and drug resistance in breast cancer. Targeting Notch signaling via inhibition of the gamma-secretase comple
Publikováno v:
Nanoscale Advances. 5:2375-2393
This review highlights recent advances and emerging applications of lab-on-a-chip (LOC)-based in vitro models to study breast cancer metastasis, diagnosis and treatment.
Autor:
Deniz Ugur, Taha Bugra Gungul, Simge Yucel, Engin Ozcivici, Ozden Yalcin-Ozuysal, Gulistan Mese
Publikováno v:
J Cell Commun Signal
Connexins (Cx) are primary components of gap junctions that selectively allow molecules to be exchanged between adjacent cells, regulating multiple cellular functions. Along with their channel forming functions, connexins play a variety of roles in d
Autor:
Zehra Elif Gunyuz, Ece Sahi-Ilhan, Cansu Kucukkose, Dogac Ipekgil, Gunes Tok, Gulistan Mese, Engin Ozcivici, Ozden Yalcin-Ozuysal
Publikováno v:
ACS Omega. 7:15769-15778
Semaphorin 6D (SEMA6D), a member of the class 6 semaphorin family, is a membrane-associated protein that plays a key role in the development of cardiac and neural tissues. A growing body of evidence suggests that SEMA6D is also involved in tumorigene
Autor:
Ismail Tahmaz, Devrim Pesen-Okvur, Burcu Firatligil-Yildirir, Muge Bilgen, Gizem Bati-Ayaz, Ozden Yalcin-Ozuysal
Publikováno v:
Biotechnology and Bioengineering. 118:3799-3810
Metastasis is one of the major obstacles for breast cancer patients. Limitations of current models demand the development of custom platforms to predict metastatic potential and homing choices of cancer cells. Here, two organ-on-chip (OoC) platforms,
Autor:
H. Cumhur Tekin, Oyku Sarigil, Kerem Delikoyun, Sena Yaman, Engin Ozcivici, Esra Yilmaz, Kubra Telli, Ozden Yalcin-Ozuysal, Muge Anil-Inevi
Publikováno v:
ACS Sensors. 6:2191-2201
In clinical practice, a variety of diagnostic applications require the identification of target cells. Density has been used as a physical marker to distinguish cell populations since metabolic activities could alter the cell densities. Magnetic levi
Publikováno v:
ACS Nano. 15:10710-10721
Accessing cell growth on adhesive substrates is critical for identifying biophysical properties of cells and their therapeutic response to drug therapies. However, optical techniques have low sensitivity, and their reliability varies with cell type,