Zobrazeno 1 - 10
of 535
pro vyhledávání: '"Ozan S."'
Autor:
Prashant Kumar, Michael Wang, Ozan S. Kumru, John M. Hickey, Julio Sanmiguel, Nerea Zabaleta, Luk H. Vandenberghe, Sangeeta B. Joshi, David B. Volkin
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 30, Iss , Pp 103-121 (2023)
Recombinant adeno-associated viruses (rAAVs) are a preferred vector system in clinical gene transfer. A fundamental challenge to formulate and deliver rAAVs as stable and efficacious vaccines is to elucidate interrelationships between the vector’s
Externí odkaz:
https://doaj.org/article/c0cdad5aefc247faaa90ba08588e0e25
Autor:
Payton A.-B. Weidenbacher, Mrinmoy Sanyal, Natalia Friedland, Shaogeng Tang, Prabhu S. Arunachalam, Mengyun Hu, Ozan S. Kumru, Mary Kate Morris, Jane Fontenot, Lisa Shirreff, Jonathan Do, Ya-Chen Cheng, Gayathri Vasudevan, Mark B. Feinberg, Francois J. Villinger, Carl Hanson, Sangeeta B. Joshi, David B. Volkin, Bali Pulendran, Peter S. Kim
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract While the rapid development of COVID-19 vaccines has been a scientific triumph, the need remains for a globally available vaccine that provides longer-lasting immunity against present and future SARS-CoV-2 variants of concern (VOCs). Here, w
Externí odkaz:
https://doaj.org/article/4b2711e833a84864a890be327d293be9
Autor:
Ozan S. Kumru, Sakshi Bajoria, Kawaljit Kaur, John M. Hickey, Greta Van Slyke, Jennifer Doering, Katherine Berman, Charles Richardson, Hans Lien, Harry Kleanthous, Nicholas J. Mantis, Sangeeta B. Joshi, David B. Volkin
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 19, Iss 2 (2023)
ABSTRACTSecond-generation COVID-19 vaccines with improved immunogenicity (e.g., breadth, duration) and availability (e.g., lower costs, refrigerator stable) are needed to enhance global coverage. In this work, we formulated a clinical-stage SARS-CoV-
Externí odkaz:
https://doaj.org/article/158fc546f0eb4b9a9cde3509161cd3e9
Autor:
Payton A.-B. Weidenbacher, Mrinmoy Sanyal, Natalia Friedland, Shaogeng Tang, Prabhu S. Arunachalam, Mengyun Hu, Ozan S. Kumru, Mary Kate Morris, Jane Fontenot, Lisa Shirreff, Jonathan Do, Ya-Chen Cheng, Gayathri Vasudevan, Mark B. Feinberg, Francois J. Villinger, Carl Hanson, Sangeeta B. Joshi, David B. Volkin, Bali Pulendran, Peter S. Kim
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/dbf7e69ac4e540d2a86ef987b054a206
Autor:
Sakshi Bajoria, Kawaljit Kaur, Ozan S. Kumru, Greta Van Slyke, Jennifer Doering, Hayley Novak, Sergio A. Rodriguez Aponte, Neil C. Dalvie, Christopher A. Naranjo, Ryan S. Johnston, Judith Maxwell Silverman, Harry Kleanthous, J. Christopher Love, Nicholas J. Mantis, Sangeeta B. Joshi, David B. Volkin
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 18, Iss 5 (2022)
Low-cost, refrigerator-stable COVID-19 vaccines will facilitate global access and improve vaccine coverage in low- and middle-income countries. To this end, subunit-based approaches targeting the receptor-binding domain (RBD) of SARS-CoV-2 Spike prot
Externí odkaz:
https://doaj.org/article/35022f23ff944bc2b948e4fb228bed37
Autor:
Prashant Kumar, Ravi S. Shukla, Ashaben Patel, Swathi R. Pullagurla, Christopher Bird, Oluwadara Ogun, Ozan S. Kumru, Ahd Hamidi, Femke Hoeksema, Christopher Yallop, Julie E. Bines, Sangeeta B. Joshi, David B. Volkin
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 17, Iss 7, Pp 2298-2310 (2021)
Formulation development was performed with the live, attenuated, human neonatal rotavirus vaccine candidate (RV3-BB) with three main objectives to facilitate use in low- and middle- income countries including (1) a liquid, 2–8°C stable vaccine, (2
Externí odkaz:
https://doaj.org/article/12c6cde616c54ca1b517d9492fd04696
Autor:
Sakshi Bajoria, Ozan S. Kumru, Jennifer Doering, Katherine Berman, Greta Van Slyke, Anneka Prigodich, Sergio A. Rodriguez-Aponte, Harry Kleanthous, J. Christopher Love, Nicholas J. Mantis, Sangeeta B. Joshi, David B. Volkin
Publikováno v:
Vaccines, Vol 11, Iss 6, p 1030 (2023)
Aluminum-salt vaccine adjuvants (alum) are commercially available as micron-sized particles with varying chemical composition and crystallinity. There are reports of enhanced adjuvanticity when the alum’s particle size is reduced to the nanometer r
Externí odkaz:
https://doaj.org/article/343ba8c292fa4103b310f647279e6dea
Autor:
Audrey Y-H Teh, Lisa Cavacini, Yue Hu, Ozan S. Kumru, Jian Xiong, David T. Bolick, Sangeeta B. Joshi, Clemens Grünwald-Gruber, Friedrich Altmann, Mark Klempner, Richard L. Guerrant, David B. Volkin, Yang Wang, Julian K-C. Ma
Publikováno v:
Gut Microbes, Vol 13, Iss 1 (2021)
Passive immunization with antibodies is a promising approach against enterotoxigenic Escherichia coli diarrhea, a prevalent disease in LMICs. The objective of this study was to investigate expression of a monoclonal anti-ETEC CfaE secretory IgA antib
Externí odkaz:
https://doaj.org/article/9adbc1d8ed9d4e8786f8aee96cdadbaa
Publikováno v:
Archives of Metallurgy and Materials, Vol 58, Iss 4, Pp 1137-1145 (2013)
Powierzchnie stalowe SAE 1020 były oddzielnie stopowane z wcześniej nałożonymi proszkami wysokowęglowego żelazo- chromu (FeCr), żelazo-molibdenu (FeMo) i żelazo-tytanu (FeTi) za pomocą techniki PTA. Dzięki zastosowaniu trzech różnych typ
Externí odkaz:
https://doaj.org/article/7bfb0fdd2fa244c2aca8ab3ded9149c6
Autor:
Sarıyer, Ozan S.
Publikováno v:
Phys. Rev. E 104, 034128 (2021)
By using frustration-preserving hard-spin mean-field theory, we investigated the phase transition dynamics in the three-dimensional field-free $\pm J$ Ising spin glass model. As the temperature $T$ is decreased from paramagnetic phase at high tempera
Externí odkaz:
http://arxiv.org/abs/2107.03981
