Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Ozama Ismail"'
Autor:
Matthew Simon, Marie Xun Wang, Ozama Ismail, Molly Braun, Abigail G. Schindler, Jesica Reemmer, Zhongya Wang, Mariya A. Haveliwala, Ryan P. O’Boyle, Warren Y. Han, Natalie Roese, Marjorie Grafe, Randall Woltjer, Detlev Boison, Jeffrey J. Iliff
Publikováno v:
Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-25 (2022)
Abstract Background Slowed clearance of amyloid β (Aβ) is believed to underlie the development of Aβ plaques that characterize Alzheimer’s disease (AD). Aβ is cleared in part by the glymphatic system, a brain-wide network of perivascular pathwa
Externí odkaz:
https://doaj.org/article/43d1f7130cf941b980fe99d7e0dc42df
Autor:
Da Ma, Holly E. Holmes, Manuel J. Cardoso, Marc Modat, Ian F. Harrison, Nick M. Powell, James M. O’Callaghan, Ozama Ismail, Ross A. Johnson, Michael J. O’Neill, Emily C. Collins, Mirza F. Beg, Karteek Popuri, Mark F. Lythgoe, Sebastien Ourselin
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Brain volume measurements extracted from structural MRI data sets are a widely accepted neuroimaging biomarker to study mouse models of neurodegeneration. Whether to acquire and analyze data in vivo or ex vivo is a crucial decision during the phase o
Externí odkaz:
https://doaj.org/article/9b84e61895284ebd9c09e6d1b92b0f14
Autor:
Ian F Harrison, Bernard Siow, Aisha B Akilo, Phoebe G Evans, Ozama Ismail, Yolanda Ohene, Payam Nahavandi, David L Thomas, Mark F Lythgoe, Jack A Wells
Publikováno v:
eLife, Vol 7 (2018)
The glymphatics system describes a CSF-mediated clearance pathway for the removal of potentially harmful molecules, such as amyloid beta, from the brain. As such, its components may represent new therapeutic targets to alleviate aberrant protein accu
Externí odkaz:
https://doaj.org/article/ac2ca34016804c4aa72b5387b52ac633
Autor:
Niall Colgan, Balaji Ganeshan, Ian F. Harrison, Ozama Ismail, Holly E. Holmes, Jack A. Wells, Nick M. Powell, James M. O'Callaghan, Michael J. O'Neill, Tracey K. Murray, Zeshan Ahmed, Emily C. Collins, Ross A. Johnson, Ashley Groves, Mark F. Lythgoe
Publikováno v:
Frontiers in Neuroscience, Vol 11 (2017)
Background: Non-invasive characterization of the pathological features of Alzheimer's disease (AD) could enhance patient management and the development of therapeutic strategies. Magnetic resonance imaging texture analysis (MRTA) has been used previo
Externí odkaz:
https://doaj.org/article/60e4232880ba4c5498d7237a5ccdcb0d
Autor:
Jing Chen, Neil Ingham, Simon Clare, Claire Raisen, Valerie E Vancollie, Ozama Ismail, Rebecca E McIntyre, Stephen H Tsang, Vinit B Mahajan, Gordon Dougan, David J Adams, Jacqueline K White, Karen P Steel
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58156 (2013)
Otitis media is a common reason for hearing loss, especially in children. Otitis media is a multifactorial disease and environmental factors, anatomic dysmorphology and genetic predisposition can all contribute to its pathogenesis. However, the reaso
Externí odkaz:
https://doaj.org/article/48ee8e9591c54975b473804e639fb7a1
Autor:
Jing Chen, Neil Ingham, Simon Clare, Claire Raisen, Valerie E. Vancollie, Ozama Ismail, Rebecca E. McIntyre, Stephen H. Tsang, Vinit B. Mahajan, Gordon Dougan, David J. Adams, Jacqueline K. White, Karen P. Steel
Publikováno v:
PLoS ONE, Vol 8, Iss 6 (2013)
Externí odkaz:
https://doaj.org/article/2b1cd17da8094f158965f50ce85ccebe
Autor:
Rebecca E McIntyre, Pavithra Lakshminarasimhan Chavali, Ozama Ismail, Damian M Carragher, Gabriela Sanchez-Andrade, Josep V Forment, Beiyuan Fu, Martin Del Castillo Velasco-Herrera, Andrew Edwards, Louise van der Weyden, Fengtang Yang, Sanger Mouse Genetics Project, Ramiro Ramirez-Solis, Jeanne Estabel, Ferdia A Gallagher, Darren W Logan, Mark J Arends, Stephen H Tsang, Vinit B Mahajan, Cheryl L Scudamore, Jacqueline K White, Stephen P Jackson, Fanni Gergely, David J Adams
Publikováno v:
PLoS Genetics, Vol 8, Iss 11, p e1003022 (2012)
Disruption of the centromere protein J gene, CENPJ (CPAP, MCPH6, SCKL4), which is a highly conserved and ubiquitiously expressed centrosomal protein, has been associated with primary microcephaly and the microcephalic primordial dwarfism disorder Sec
Externí odkaz:
https://doaj.org/article/59c11391f61449a4aa008d3e380c5a64
Autor:
Anna M Migdalska, Louise van der Weyden, Ozama Ismail, Jacqueline K White, Sanger Mouse Genetics Project, Gabriela Sánchez-Andrade, Darren W Logan, Mark J Arends, David J Adams
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e29681 (2012)
Haploinsufficiency of part of human chromosome 21 results in a rare condition known as Monosomy 21. This disease displays a variety of clinical phenotypes, including intellectual disability, craniofacial dysmorphology, skeletal and cardiac abnormalit
Externí odkaz:
https://doaj.org/article/d64c6d8c0c494752a8171db8106e5731
Autor:
Anna M. Migdalska, Louise van der Weyden, Ozama Ismail, Jacqueline K. White, Sanger Mouse Genetics Project, Gabriela Sánchez-Andrade, Darren W. Logan, Mark J. Arends, David J. Adams
Publikováno v:
PLoS ONE, Vol 7, Iss 3 (2012)
Externí odkaz:
https://doaj.org/article/78c749d63ed349dd872bdffcf8046672
Autor:
Ian F. Harrison, Phoebe G Evans, Enrique Miranda, A. Alves, Payam Nahavandi, David L. Thomas, Yolanda Ohene, Ozama Ismail, Magdalena Sokolska, Mark F. Lythgoe, Jack A. Wells
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Nature Communications
Nature Communications
The blood–cerebrospinal fluid barrier (BCSFB) is a highly dynamic transport interface that serves brain homeostasis. To date, however, understanding of its role in brain development and pathology has been hindered by the absence of a non-invasive t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63e4ea17dbf06ecb6fd9831cab277f66
https://doaj.org/article/621240a9bcb347539473c1a18488fa57
https://doaj.org/article/621240a9bcb347539473c1a18488fa57