Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Oz Solomon"'
Autor:
Renata Ferrarotto, Vasudha Mishra, Elad Herz, Adar Yaacov, Oz Solomon, Rami Rauch, Adi Mondshine, Maria Motin, Tal Leibovich-Rivkin, Matti Davis, Joel Kaye, Christopher R. Weber, Le Shen, Alexander T. Pearson, Ari J. Rosenberg, Xiangying Chen, Alka Singh, Jon C. Aster, Nishant Agrawal, Evgeny Izumchenko
Publikováno v:
Cell Death and Disease, Vol 13, Iss 8, Pp 1-11 (2022)
Abstract Adenoid cystic carcinoma (ACC) is an aggressive salivary gland malignancy with limited treatment options for recurrent or metastatic disease. Due to chemotherapy resistance and lack of targeted therapeutic approaches, current treatment optio
Externí odkaz:
https://doaj.org/article/56e0238430084912a4c2eb44ee06b45b
Publikováno v:
BMC Bioinformatics, Vol 19, Iss 1, Pp 1-15 (2018)
Abstract Background Synthetic biology and related techniques enable genome scale high-throughput investigation of the effect on organism fitness of different gene knock-downs/outs and of other modifications of genomic sequence. Results We develop sta
Externí odkaz:
https://doaj.org/article/01e65b8e1c784386a07261ad3b971c11
Autor:
Oz Solomon, Ayelet Di Segni, Karen Cesarkas, Hagit T. Porath, Victoria Marcu-Malina, Orel Mizrahi, Noam Stern-Ginossar, Nitzan Kol, Sarit Farage-Barhom, Efrat Glick-Saar, Yaniv Lerenthal, Erez Y. Levanon, Ninette Amariglio, Ron Unger, Itamar Goldstein, Eran Eyal, Gidi Rechavi
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Adenosine deaminase acting on RNA 1 (ADAR1) edits adenosine to inosine. Here the authors, using parallel analysis of RNA secondary structure sequencing, provide evidence that ADAR1 induces sequence-context-dependent RNA secondary structures changes,
Externí odkaz:
https://doaj.org/article/135bc3a86dbd4e62a8694058deaacfb0
Autor:
Lior Levy, Leon Anavy, Oz Solomon, Roni Cohen, Michal Brunwasser-Meirom, Shilo Ohayon, Orna Atar, Sarah Goldberg, Zohar Yakhini, Roee Amit
Publikováno v:
Cell Reports, Vol 21, Iss 3, Pp 845-858 (2017)
We use an oligonucleotide library of >10,000 variants to identify an insulation mechanism encoded within a subset of σ54 promoters. Insulation manifests itself as reduced protein expression for a downstream gene that is expressed by transcriptional
Externí odkaz:
https://doaj.org/article/7d4fd9ada4074558bd5319622a2cf784
Autor:
Eyal Greenberg, Gideon Rechavi, Ninette Amariglio, Oz Solomon, Jacob Schachter, Gal Markel, Eran Eyal
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27400 (2011)
Micro-RNAs (miRNAs) are small non-coding RNAs that regulate gene products at the post-transcriptional level. It is thought that loss of cell regulation by miRNAs supports cancer development. Based on whole genome sequencing of a melanoma tumor, we pr
Externí odkaz:
https://doaj.org/article/4c23e87e3d324a8ba7135916b9623ebb
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Scientific Reports
Scientific Reports
Recent developments in personalized medicine are based on molecular measurement steps that guide personally adjusted medical decisions. A central approach to molecular profiling consists of measuring DNA, RNA, and/or proteins in tissue samples, most
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::736650bc6832d5a89a433c22b54ad12f
http://link.springer.com/article/10.1038/s41598-019-51634-7
http://link.springer.com/article/10.1038/s41598-019-51634-7
Autor:
Zohar Yakhini, Lisa Kermas, Oz Solomon, Roee Amit, Leon Anavy, Sarah Goldberg, Noa Eden, Orna Atar, Beate Kaufmann, Or Willinger
SummaryNature provides a rich toolbox of dynamic nucleic acid structures that are widespread in cells and affect multiple biological processes1. Recently, non-canonical structures gained renewed scientific and biotechnological interest2,3. One partic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75f2d26d9539fe59f09da61faf312fce
Autor:
G. Rechavi, Oz Solomon, Yaniv Lerenthal, Ron Unger, Victoria Marcu-Malina, Ayelet Di Segni, Hagit T. Porath, Erez Y. Levanon, Karen Cesarkas, Nitzan Kol, Ninette Amariglio, Orel Mizrahi, Eran Eyal, Noam Stern-Ginossar, Efrat Glick-Saar, Itamar Goldstein, Sarit Farage-Barhom
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Nature Communications
Nature Communications
Adenosine deaminase acting on RNA 1 (ADAR1) is the master RNA editor, catalyzing the deamination of adenosine to inosine. RNA editing is vital for preventing abnormal activation of cytosolic nucleic acid sensing pathways by self-double-stranded RNAs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f10a55c86cb86840b32c14b3bb151ed
http://link.springer.com/article/10.1038/s41467-017-01458-8
http://link.springer.com/article/10.1038/s41467-017-01458-8
Autor:
Roee Amit, Noa Katz, Beate Kaufmann, Orna Atar, Sarah Goldberg, Roni Cohen, Zohar Yakhini, Oz Solomon
Publikováno v:
ACS synthetic biology. 7(12)
We study translation repression in bacteria by engineering a regulatory circuit that functions as a binding assay for RNA binding proteins (RBP) in vivo. We do so by inducing expression of a fluorescent protein-RBP chimera, together with encoding its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::522b9b7ae0130eb8b3d18bf44a59c4ab
https://pubmed.ncbi.nlm.nih.gov/30408420
https://pubmed.ncbi.nlm.nih.gov/30408420
Autor:
Roee Amit, Oz Solomon, Noa Katz, Sarah Goldberg, Orna Atar, Beate Kaufmann, Zohar Yakhini, Roni Cohen
Publikováno v:
Cell systems. 9(1)
Summary The construction of complex gene-regulatory networks requires both inhibitory and upregulatory modules. However, the vast majority of RNA-based regulatory “parts” are inhibitory. Using a synthetic biology approach combined with SHAPE-seq,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97ffbb1cc314e3509d0aaa1a66cdd7ec
https://pubmed.ncbi.nlm.nih.gov/31129060
https://pubmed.ncbi.nlm.nih.gov/31129060