Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Oz Pomp"'
Autor:
Abdulla Berjis, Deeksha Muthumani, Oscar A. Aguilar, Oz Pomp, Omar Johnson, Amanda V. Finck, Nils W. Engel, Linhui Chen, Nicolas Plachta, John Scholler, Lewis L. Lanier, Carl H. June, Neil C. Sheppard
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Human natural killer (NK) cell-based therapies are under assessment for treating various cancers, but cryopreservation reduces both the recovery and function of NK cells, thereby limiting their therapeutic feasibility. Using cryopreservation
Externí odkaz:
https://doaj.org/article/3fd910c3f98f4e43883f2a9ab9531d8c
Autor:
Robin M. Skory, Adam A. Moverley, Goli Ardestani, Yanina Alvarez, Ana Domingo-Muelas, Oz Pomp, Blake Hernandez, Piotr Tetlak, Stephanie Bissiere, Claudio D. Stern, Denny Sakkas, Nicolas Plachta
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract During preimplantation development, contractile forces generated at the apical cortex segregate cells into inner and outer positions of the embryo, establishing the inner cell mass (ICM) and trophectoderm. To which extent these forces influe
Externí odkaz:
https://doaj.org/article/550f65f5dde3438fb4baa68658fe2d56
Autor:
Robin Skory, Ana Domingo-Muelas, Adam A. Moverley, Goli Ardestani, Oz Pomp, Carmen Rubio Lluesa, Piotr Tetlak, Blake Hernandez, Luis Navarro Sanchez, Carmen M. Garcia Pascual, Stephanie Bissiere, Denny Sakkas, Carlos Simon, Nicolas D. Plachta
Publikováno v:
Fertility and Sterility. 118:e73
Autor:
Oz Pomp, Hui Yi Grace Lim, Robin M. Skory, Adam A. Moverley, Piotr Tetlak, Stephanie Bissiere, Nicolas Plachta
Publikováno v:
Nature cell biology. 24(2)
During mammalian development, the first asymmetric cell divisions segregate cells into inner and outer positions of the embryo to establish the pluripotent and trophectoderm lineages. Typically, polarity components differentially regulate the mitotic
Autor:
Bruno Reversade, Puck Wee Chan, Naveenan Navaratnam, Hülya Kayserili, Alvin Yu Jin Ng, Thong Teck Tan, Oz Pomp, Carine Bonnard, Rishita Changede, Byrappa Venkatesh, David Carling, Sumanty Tohari, Kakaly Ghosh, Umut Altunoglu
Publikováno v:
Journal of experimental medicine, 217(12):e20191561. Rockefeller University Press
The Journal of Experimental Medicine
The Journal of Experimental Medicine
A germline homozygous loss-of-function mutation in NUAK2 causes human fetal death due to anencephaly. Our functional tests establish that NUAK2, operating on the Hippo signaling axis, is an essential kinase that regulates cytoskeletal processes that
Autor:
Hpone Myint Kyaw, Mei Bigliardi-Qi, Thirumalai Venkatesan, Viknish Krishnan-Kutty, Michal Marcin Dykas, Oz Pomp, Paul L. Bigliardi, Kingshuk Poddar
Publikováno v:
Experimental Dermatology. 26:281-284
Autor:
Hiroshi Hamada, Bruno Reversade, Artina Metoska, Fui Mee Ng, Jeffrey Hill, Patrick Cozzone, Nithya Baburajendran, Hülya Kayserili, Oz Pomp, Nathalie Escande-Beillard, Joyner Wong, Abigail Loh, Kohei Kanata, Sahar N. Saleem, Joanes Grandjean, Yui Hashimoto, E. Beillard, Umut Altunoglu, Hidetaka Shiratori, Maha S. Zaki
Publikováno v:
Neuron, 107, 82-94 e6
Neuron, 107(1), 82-94.e6. Cell Press
Neuron, 107, 1, pp. 82-94 e6
Neuron, 107(1), 82-94.e6. Cell Press
Neuron, 107, 1, pp. 82-94 e6
Patients lacking PYCR2, a mitochondrial enzyme that synthesizes proline, display postnatal degenerative microcephaly with hypomyelination. Here we report the crystal structure of the PYCR2 apo-enzyme and show that a novel germline p.Gly249Val mutatio
Autor:
Jeremy F. Reiter, Timothy W. Yu, Thong Teck Tan, Mohammad Shboul, Anas M. Alazami, Bruno Reversade, Christopher A. Walsh, Wen Fan Hu, Matthew P. Harris, Mollie B. Woodworth, Hanan Hamamy, Grace Selva Raj, Mohammed Al-Owain, Katrin Henke, Ganeshwaran H. Mochida, Amira Masri, Andrew Kodani, Muna Al Saffar, Carine Bonnard, Jennifer N. Partlow, Mohammed S. Al-Dosari, Oz Pomp, Fowzan S. Alkuraya, Tawfeg Ben-Omran
Publikováno v:
Neuron, vol 84, iss 6
Neuron, 84(6), 1240-1257. Cell Press
Neuron, 84(6), 1240-1257. Cell Press
Katanin is a microtubule-severing complex whose catalytic activities are well characterized, but whose invivo functions are incompletely understood. Human mutations in KATNB1, which encodes the noncatalytic regulatory p80 subunit of katanin, cause se
Autor:
Daiju Kitagawa, Mingyue Jin, Takuo Yasunaga, Shigeru Matsumura, Takaki Miyata, Ken'ya Furuta, Shinji Hirotsune, Oz Pomp, Bruno Reversade, Tomoyasu Shinoda, Shiori Toba, Kazuhiro Oiwa, Thong Teck Tan, Takayuki Torisawa
Publikováno v:
Scientific Reports
Scientific reports, 7. Nature Publishing Group
Scientific reports, 7. Nature Publishing Group
Human mutations in KATNB1 (p80) cause severe congenital cortical malformations, which encompass the clinical features of both microcephaly and lissencephaly. Although p80 plays critical roles during brain development, the underlying mechanisms remain
Autor:
Alan Colman, Oz Pomp
Publikováno v:
BioEssays. 35:271-280
The ability to convert human somatic cells into induced pluripotent stem cells (iPSCs) is allowing the production of custom-tailored cells for drug discovery and for the study of disease phenotypes at the cellular and molecular level. IPSCs have been